Halofuginone induces matrix metalloproteinases in rat hepatic stellate cells via activation of p38 and NFkappaB. (Q40314036)

19 September 2017

Halofuginone induces matrix metalloproteinases in rat hepatic stellate cells via activation of p38 and NFkappaB. (English)

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19 September 2017

6

Detlef Schuppan

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19 September 2017

Yury Popov

1

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19 September 2017

Eleonora Patsenker

2

1 reference

19 September 2017

Michael Bauer

3

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19 September 2017

Edith Niedobitek

4

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19 September 2017

Anja Schulze-Krebs

5

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19 September 2017

language of work or name

English

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publication date

17 February 2006

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Journal of Biological Chemistry

19 September 2017

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19 September 2017

281

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19 September 2017

22

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19 September 2017

15090-15098

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Altered balance between matrix metalloproteinases and their inhibitors in experimental biliary fibrosis

19 September 2017

1 reference

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A randomized, controlled trial of maintenance interferon therapy for patients with chronic hepatitis C virus and persistent viremia

21 January 2018

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Regression of liver fibrosis after biliary drainage in patients with chronic pancreatitis and stenosis of the common bile duct

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M600030200

Histological outcome during long-term lamivudine therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600030200

Halofuginone: a novel antifibrotic therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600030200

Halofuginone: an inhibitor of collagen type I synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600030200

Halofuginone inhibition of COL1A2 promoter activity via a c-Jun-dependent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600030200

Halofuginone to prevent and treat thioacetamide-induced liver fibrosis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600030200

A histone deacetylase inhibitor, trichostatin A, suppresses myofibroblastic differentiation of rat hepatic stellate cells in primary culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600030200

Hepatocyte transplantation activates hepatic stellate cells with beneficial modulation of cell engraftment in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600030200

Hepatitis C virus-replicating hepatocytes induce fibrogenic activation of hepatic stellate cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600030200

Reciprocal modulation of matrix metalloproteinase-13 and type I collagen genes in rat hepatic stellate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600030200

Extracellular matrix degradation and the role of hepatic stellate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600030200

Progelatinase A is produced and activated by rat hepatic stellate cells and promotes their proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600030200

Delivery of matrix metalloproteinase-1 attenuates established liver fibrosis in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600030200

Treatment with human metalloproteinase-8 gene delivery ameliorates experimental rat liver cirrhosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600030200

Halofuginone to treat fibrosis in chronic graft-versus-host disease and scleroderma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600030200

NF-kappaB inhibits expression of the alpha1(I) collagen gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600030200

Persistent activation of nuclear factor-kappaB in cultured rat hepatic stellate cells involves the induction of potentially novel Rel-like factors and prolonged changes in the expression of IkappaB family proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600030200

Stress-activated protein kinases in the activation of rat hepatic stellate cells in culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600030200

TAK1/JNK and p38 have opposite effects on rat hepatic stellate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600030200

p38 MAPK mediates the regulation of alpha1(I) procollagen mRNA levels by TNF-alpha and TGF-beta in a cell line of rat hepatic stellate cells(1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600030200

Activation of p38 alpha MAPK enhances collagenase-1 (matrix metalloproteinase (MMP)-1) and stromelysin-1 (MMP-3) expression by mRNA stabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600030200

Enhancement of fibroblast collagenase-1 (MMP-1) gene expression by tumor promoter okadaic acid is mediated by stress-activated protein kinases Jun N-terminal kinase and p38.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600030200

Induction of collagenase-3 (MMP-13) expression in human skin fibroblasts by three-dimensional collagen is mediated by p38 mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600030200

An oral endothelin-A receptor antagonist blocks collagen synthesis and deposition in advanced rat liver fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600030200

21 January 2018

Identifiers

DOI

10.1074/JBC.M600030200

1 reference

19 September 2017

1 reference