Proteasome inhibition induces hepatic stellate cell apoptosis (Q40324324)

19 September 2017

Proteasome inhibition induces hepatic stellate cell apoptosis (English)

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19 September 2017

6

Gregory J Gores

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19 September 2017

Akira Anan

1

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19 September 2017

Edwina S Baskin-Bey

2

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19 September 2017

Steven F Bronk

3

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19 September 2017

Nathan W Werneburg

4

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19 September 2017

Vijay H Shah

5

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19 September 2017

language of work or name

English

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publication date

1 February 2006

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19 September 2017

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19 September 2017

43

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19 September 2017

2

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19 September 2017

335-344

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Phagocytosis-induced apoptosis in macrophages is mediated by up-regulation and activation of the Bcl-2 homology domain 3-only protein Bim.

19 September 2017

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Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury

21 January 2018

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7 January 2021

History, heterogeneity, developmental biology, and functions of quiescent hepatic stellate cells

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7 January 2021

Reversibility of liver fibrosis and cirrhosis following treatment for hepatitis C.

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7 January 2021

Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors

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7 January 2021

Hepatic stellate cell behavior during resolution of liver injury

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7 January 2021

Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in rats

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7 January 2021

Inhibition of inhibitor of kappaB kinases stimulates hepatic stellate cell apoptosis and accelerated recovery from rat liver fibrosis.

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7 January 2021

Persistent activation of nuclear factor-kappaB in cultured rat hepatic stellate cells involves the induction of potentially novel Rel-like factors and prolonged changes in the expression of IkappaB family proteins.

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7 January 2021

Therapeutic potential of inhibition of the NF-kappaB pathway in the treatment of inflammation and cancer

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7 January 2021

Novel sulfasalazine analogues with enhanced NF-kB inhibitory and apoptosis promoting activity

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7 January 2021

NF-kappaB at the crossroads of life and death

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7 January 2021

Evodiamine abolishes constitutive and inducible NF-kappaB activation by inhibiting IkappaBalpha kinase activation, thereby suppressing NF-kappaB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasion

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7 January 2021

A proteasome inhibitor prevents activation of NF-kappa B and stabilizes a newly phosphorylated form of I kappa B-alpha that is still bound to NF-kappa B

1 reference

7 January 2021

Key roles of BIM-driven apoptosis in epithelial tumors and rational chemotherapy.

1 reference

7 January 2021

Human hepatic stellate cell lines, LX-1 and LX-2: new tools for analysis of hepatic fibrosis.

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7 January 2021

Regulation of hepatic eNOS by caveolin and calmodulin after bile duct ligation in rats

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7 January 2021

Purified Rat Liver Fat-Storing Cells in Culture Divide and Contain Collagen

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7 January 2021

Cathepsin B contributes to TNF-alpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c

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7 January 2021

Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alpha expression via a lysosomal pathway

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7 January 2021

Kupffer cell engulfment of apoptotic bodies stimulates death ligand and cytokine expression

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7 January 2021

Cathepsin B contributes to bile salt-induced apoptosis of rat hepatocytes

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7 January 2021

Hepatocyte apoptosis after bile duct ligation in the mouse involves Fas.

1 reference

7 January 2021

Cathepsin B inactivation attenuates hepatocyte apoptosis and liver damage in steatotic livers after cold ischemia-warm reperfusion injury

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7 January 2021

Proteasome inhibitors potentiate leukemic cell apoptosis induced by the cyclin-dependent kinase inhibitor flavopiridol through a SAPK/JNK- and NF-κB-dependent process

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7 January 2021

Bcl-2-family proteins and the role of mitochondria in apoptosis

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7 January 2021

The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis

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7 January 2021

Macrophages require constitutive NF-kappaB activation to maintain A1 expression and mitochondrial homeostasis

1 reference

7 January 2021

Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function.

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7 January 2021

Activated stellate cells express the TRAIL receptor-2/death receptor-5 and undergo TRAIL-mediated apoptosis.

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7 January 2021

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7 January 2021

The role and regulation of hepatic stellate cell apoptosis in reversal of liver fibrosis

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7 January 2021

The anti-apoptotic activities of Rel and RelA required during B-cell maturation involve the regulation of Bcl-2 expression

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7 January 2021

Biologic sequelae of nuclear factor-kappaB blockade in multiple myeloma: therapeutic applications

1 reference

7 January 2021

Commitment of bone marrow cells to hepatic stellate cells in mouse

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7 January 2021

Purified hematopoietic stem cells can differentiate into hepatocytes in vivo.

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7 January 2021

Liver from bone marrow in humans.

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7 January 2021

Inhibition of JNK activation through NF-kappaB target genes

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7 January 2021

Proteasome inhibitor MG132 upregulates death receptor 5 and cooperates with Apo2L/TRAIL to induce apoptosis in Bax-proficient and -deficient cells

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7 January 2021

Regulation of apoptosis proteins in cancer cells by ubiquitin

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7 January 2021

Molecular sequelae of proteasome inhibition in human multiple myeloma cells

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7 January 2021

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

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7 January 2021

Identifiers

DOI

10.1002/HEP.21036

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19 September 2017

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