Sialylation enhances the secretion of neurotoxic amyloid-beta peptides (Q40330052)

19 September 2017

title

Sialylation enhances the secretion of neurotoxic amyloid-beta peptides (English)

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19 September 2017

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Kazuhiro Nakagawa

1

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19 September 2017

Shinobu Kitazume

2

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19 September 2017

Ritsuko Oka

3

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19 September 2017

Kei Maruyama

4

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19 September 2017

Takaomi C Saido

5

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19 September 2017

Yuji Sato

6

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19 September 2017

Tamao Endo

7

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19 September 2017

Yasuhiro Hashimoto

8

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19 September 2017

language of work or name

English

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publication date

12 January 2006

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Journal of Neurochemistry

19 September 2017

published in

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19 September 2017

volume

96

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19 September 2017

issue

4

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19 September 2017

page(s)

924-933

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Post-translational processing of beta-secretase (beta-amyloid-converting enzyme) and its ectodomain shedding. The pro- and transmembrane/cytosolic domains affect its cellular activity and amyloid-beta production

19 September 2017

cites work

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BACE1 is the major beta-secretase for generation of Abeta peptides by neurons

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Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

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Expression cloning of the Golgi CMP-sialic acid transporter

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Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease

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The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

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Binding of F-spondin to amyloid-beta precursor protein: a candidate amyloid-beta precursor protein ligand that modulates amyloid-beta precursor protein cleavage

21 January 2018

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Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease

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Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase

21 January 2018

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Alzheimer's beta-secretase, beta-site amyloid precursor protein-cleaving enzyme, is responsible for cleavage secretion of a Golgi-resident sialyltransferase

21 January 2018

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Characterization of alpha 2,6-sialyltransferase cleavage by Alzheimer's beta -secretase (BACE1).

21 January 2018

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In vivo cleavage of alpha2,6-sialyltransferase by Alzheimer beta-secretase

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The relationship between ST6Gal I Golgi retention and its cleavage-secretion

21 January 2018

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Membrane-anchored metalloprotease MDC9 has an alpha-secretase activity responsible for processing the amyloid precursor protein

21 January 2018

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease

21 January 2018

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Formation of amyloid-like fibrils in COS cells overexpressing part of the Alzheimer amyloid protein precursor

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The role of the protein glycosylation state in the control of cellular transport of the amyloid beta precursor protein

21 January 2018

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The role of glycosylation in synthesis and secretion of beta-amyloid precursor protein by Chinese hamster ovary cells

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Soluble derivatives of beta/A4 amyloid protein precursor in human cerebrospinal fluid are both N- and O-glycosylated

21 January 2018

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Purification and cloning of amyloid precursor protein beta-secretase from human brain

21 January 2018

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Protein kinase C-dependent alpha-secretase competes with beta-secretase for cleavage of amyloid-beta precursor protein in the trans-golgi network

21 January 2018

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Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

21 January 2018

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Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

21 January 2018

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Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease

21 January 2018

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Mutation of potential N-linked glycosylation sites in the Alzheimer's disease amyloid precursor protein (APP).

21 January 2018

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10.1111/J.1471-4159.2005.03595.X

21 January 2018

Identifiers

DOI

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19 September 2017

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