Rapamycin inhibits hTERT telomerase mRNA expression, independent of cell cycle arrest. (Q40358053)

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8 January 2020

title

Rapamycin inhibits hTERT telomerase mRNA expression, independent of cell cycle arrest (English)

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8 January 2020

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4

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8 January 2020

author name string

Victoria L Bae-Jump

1

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8 January 2020

Chunxiao Zhou

2

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8 January 2020

Paola A Gehrig

3

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8 January 2020

John F Boggess

5

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8 January 2020

language of work or name

English

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publication date

24 October 2005

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8 January 2020

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8 January 2020

volume

100

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issue

3

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page(s)

487-494

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Mammalian target of rapamycin: immunosuppressive drugs uncover a novel pathway of cytokine receptor signaling.

8 January 2020

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AKT plays a central role in tumorigenesis

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AKT and mTOR phosphorylation is frequently detected in ovarian cancer and can be targeted to disrupt ovarian tumor cell growth

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Mutation of the PIK3CA gene in ovarian and breast cancer

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Telomerase and human tumorigenesis

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Human telomerase and its regulation

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Telomerase activity in the female reproductive tract and neoplasms

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Telomerase activity in gynecologic tumors

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Telomerase activity and expression of telomerase RNA component and telomerase catalytic subunit gene in cervical cancer

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Methylation status and expression of human telomerase reverse transcriptase in ovarian and cervical cancer.

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Telomerase in relation to clinicopathologic prognostic factors and survival in cervical cancer

7 January 2021

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Differential telomerase activity, expression of the telomerase catalytic sub-unit and telomerase-RNA in ovarian tumors

7 January 2021

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Expression of human telomerase subunits in ovarian malignant, borderline and benign tumors

7 January 2021

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Human telomerase reverse transcriptase mRNA expression assessed by real-time reverse transcription polymerase chain reaction predicts chemosensitivity in patients with ovarian carcinoma.

7 January 2021

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Induction of hTERT expression and phosphorylation by estrogen via Akt cascade in human ovarian cancer cell lines

7 January 2021

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An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice

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Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR.

7 January 2021

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Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k.

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Cell cycle-dependent modulation of telomerase activity in tumor cells.

7 January 2021

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Lack of cell cycle regulation of telomerase activity in human cells

7 January 2021

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Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin.

7 January 2021

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Rapamycin inhibits E2F-dependent expression of minichromosome maintenance proteins in vascular smooth muscle cells

7 January 2021

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Upstream and downstream of mTOR

7 January 2021

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Rapamycin inhibition of the G1 to S transition is mediated by effects on cyclin D1 mRNA and protein stability

7 January 2021

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Frequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas

7 January 2021

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Epigenetic and genetic alternation of PTEN in cervical neoplasm.

7 January 2021

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mTOR, a novel target in breast cancer: the effect of CCI-779, an mTOR inhibitor, in preclinical models of breast cancer

7 January 2021

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10.1016/J.YGYNO.2005.08.053

7 January 2021

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16249016%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

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