JAK1 and Tyk2 activation by the homologous polycythemia vera JAK2 V617F mutation: cross-talk with IGF1 receptor. (Q40359732)

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8 January 2020

title

JAK1 and Tyk2 activation by the homologous polycythemia vera JAK2 V617F mutation: cross-talk with IGF1 receptor (English)

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8 January 2020

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Jean-Baptiste Demoulin

3

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8 January 2020

Stefan N Constantinescu

5

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8 January 2020

William Vainchenker

4

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8 January 2020

author name string

Judith Staerk

1

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8 January 2020

Anders Kallin

2

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8 January 2020

language of work or name

English

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publication date

19 October 2005

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Journal of Biological Chemistry

8 January 2020

published in

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8 January 2020

volume

280

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8 January 2020

issue

51

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8 January 2020

page(s)

41893-41899

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A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera

8 January 2020

cites work

1 reference

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Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis

21 January 2018

1 reference

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A gain-of-function mutation of JAK2 in myeloproliferative disorders

21 January 2018

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Identification of an acquired JAK2 mutation in polycythemia vera

21 January 2018

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Role of tyrosine kinases and phosphatases in polycythemia vera.

21 January 2018

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21 January 2018

The Janus kinases (Jaks)

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Mutation in the Jak kinase JH2 domain hyperactivates Drosophila and mammalian Jak-Stat pathways

21 January 2018

1 reference

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Complex effects of naturally occurring mutations in the JAK3 pseudokinase domain: evidence for interactions between the kinase and pseudokinase domains

21 January 2018

1 reference

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Regulation of the Jak2 tyrosine kinase by its pseudokinase domain

21 January 2018

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Tyrosine phosphorylation of Jak2 in the JH2 domain inhibits cytokine signaling

21 January 2018

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Autophosphorylation of JAK2 on tyrosines 221 and 570 regulates its activity

21 January 2018

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Tyrosine 813 is a site of JAK2 autophosphorylation critical for activation of JAK2 by SH2-B beta

21 January 2018

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Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loop

21 January 2018

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Distinct domains of the protein tyrosine kinase tyk2 required for binding of interferon-alpha/beta and for signal transduction.

21 January 2018

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A dual role for the kinase-like domain of the tyrosine kinase Tyk2 in interferon-alpha signaling

21 January 2018

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Interferon-alpha-dependent activation of Tyk2 requires phosphorylation of positive regulatory tyrosines by another kinase

21 January 2018

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Generation of mammalian cells stably expressing multiple genes at predetermined levels.

21 January 2018

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Active and inactive orientations of the transmembrane and cytosolic domains of the erythropoietin receptor dimer

21 January 2018

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The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction

21 January 2018

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Use of a selectable marker regulated by alpha interferon to obtain mutations in the signaling pathway

21 January 2018

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A protein tyrosine kinase in the interferon alpha/beta signaling pathway

21 January 2018

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Human interleukin-10-related T cell-derived inducible factor: molecular cloning and functional characterization as an hepatocyte-stimulating factor

21 January 2018

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The membrane proximal region of the cytoplasmic domain of the growth hormone receptor is involved in the activation of Stat 3

21 January 2018

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Structure of the FGF receptor tyrosine kinase domain reveals a novel autoinhibitory mechanism

21 January 2018

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Prediction of the structure of human Janus kinase 2 (JAK2) comprising the two carboxy-terminal domains reveals a mechanism for autoregulation

21 January 2018

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Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

21 January 2018

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Regions of the JAK2 tyrosine kinase required for coupling to the growth hormone receptor

21 January 2018

1 reference

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Expression, characterization, and genomic structure of carp JAK1 kinase gene

21 January 2018

1 reference

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Mechanism of STAT3 activation by insulin-like growth factor I receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.C500358200

Interaction of Janus kinases JAK-1 and JAK-2 with the insulin receptor and the insulin-like growth factor-1 receptor

21 January 2018

1 reference

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Truncated erythropoietin receptor causes dominantly inherited benign human erythrocytosis

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.C500358200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16239216%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

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