WFS1 is a novel component of the unfolded protein response and maintains homeostasis of the endoplasmic reticulum in pancreatic beta-cells (Q40367285)

19 September 2017

WFS1 is a novel component of the unfolded protein response and maintains homeostasis of the endoplasmic reticulum in pancreatic beta-cells (English)

1 reference

19 September 2017

endoplasmic reticulum

1 reference

Sonya G Fonseca

1

1 reference

19 September 2017

Mariko Fukuma

2

1 reference

19 September 2017

Kathryn L Lipson

3

1 reference

19 September 2017

Linh X Nguyen

4

1 reference

19 September 2017

Jenny R Allen

5

1 reference

19 September 2017

Yoshitomo Oka

6

1 reference

19 September 2017

Fumihiko Urano

7

1 reference

19 September 2017

language of work or name

English

0 references

publication date

29 September 2005

1 reference

Journal of Biological Chemistry

19 September 2017

7

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

19 September 2017

280

1 reference

19 September 2017

47

1 reference

19 September 2017

39609-39615

1 reference

Wolfram (DIDMOAD) syndrome.

19 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507426200

Wolfram syndrome: Evidence of a diffuse neurodegenerative disease by magnetic resonance imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507426200

A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507426200

Diabetes insipidus, diabetes mellitus, optic atrophy and deafness (DIDMOAD) caused by mutations in a novel gene (wolframin) coding for a predicted transmembrane protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507426200

Wolframin expression induces novel ion channel activity in endoplasmic reticulum membranes and increases intracellular calcium

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507426200

Transcriptional and translational control in the Mammalian unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507426200

The unfolded protein response in nutrient sensing and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507426200

Tripartite management of unfolded proteins in the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507426200

High white blood cell count is associated with a worsening of insulin sensitivity and predicts the development of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507426200

The double-stranded RNA-activated protein kinase mediates viral-induced encephalitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507426200

A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507426200

A transgenic mouse model for monitoring endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507426200

Cloning of mammalian Ire1 reveals diversity in the ER stress responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507426200

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507426200

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507426200

Mediation of TNF receptor-associated factor effector functions by apoptosis signal-regulating kinase-1 (ASK1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507426200

ASK1 is essential for JNK/SAPK activation by TRAF2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507426200

ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507426200

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507426200

Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507426200

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507426200

Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507426200

ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507426200

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507426200

Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507426200

Perk is essential for translational regulation and cell survival during the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507426200

EIF2AK3, encoding translation initiation factor 2-alpha kinase 3, is mutated in patients with Wolcott-Rallison syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507426200

Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507426200

The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507426200

WFS1 (Wolfram syndrome 1) gene product: predominant subcellular localization to endoplasmic reticulum in cultured cells and neuronal expression in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507426200

Wolfram syndrome: structural and functional analyses of mutant and wild-type wolframin, the WFS1 gene product.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507426200

Intracellular signaling from the endoplasmic reticulum to the nucleus: the unfolded protein response in yeast and mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507426200

Disruption of the WFS1 gene in mice causes progressive beta-cell loss and impaired stimulus-secretion coupling in insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507426200

Regulated translation initiation controls stress-induced gene expression in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507426200

21 January 2018

Identifiers

DOI

10.1074/JBC.M507426200

1 reference

19 September 2017

1 reference