Mutations in the TLR3 signaling pathway and beyond in adult patients with herpes simplex encephalitis (Q40380432)

20 September 2017

title

Mutations in the TLR3 signaling pathway and beyond in adult patients with herpes simplex encephalitis (English)

1 reference

20 September 2017

0 references

E Bach

4

0 references

Mette Christiansen

object named as

M Christiansen

8

0 references

Lars Østergaard

object named as

L Østergaard

6

0 references

author name string

N Mørk

1

1 reference

20 September 2017

E Kofod-Olsen

2

1 reference

20 September 2017

K B Sørensen

3

1 reference

20 September 2017

T F Ørntoft

5

1 reference

20 September 2017

S R Paludan

7

1 reference

20 September 2017

T H Mogensen

9

1 reference

20 September 2017

publication date

29 October 2015

1 reference

20 September 2017

1 reference

20 September 2017

volume

16

1 reference

20 September 2017

issue

8

1 reference

20 September 2017

page(s)

552-566

1 reference

TLR3 deficiency in patients with herpes simplex encephalitis

20 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Recognition of herpesviruses by the innate immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

CD8(+) T cells can block herpes simplex virus type 1 (HSV-1) reactivation from latency in sensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Severe herpesvirus infections in an adolescent without natural killer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Toll-like receptor 9-mediated recognition of Herpes simplex virus-2 by plasmacytoid dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Herpes simplex virus type 1 activates murine natural interferon-producing cells through toll-like receptor 9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Type I interferon production during herpes simplex virus infection is controlled by cell-type-specific viral recognition through Toll-like receptor 9, the mitochondrial antiviral signaling protein pathway, and novel recognition systems.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

TLR2 and TLR9 synergistically control herpes simplex virus infection in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

IFI16 is an innate immune sensor for intracellular DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Double-stranded RNA is produced by positive-strand RNA viruses and DNA viruses but not in detectable amounts by negative-strand RNA viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Early innate recognition of herpes simplex virus in human primary macrophages is mediated via the MDA5/MAVS-dependent and MDA5/MAVS/RNA polymerase III-independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Herpes simplex virus encephalitis in human UNC-93B deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Herpes simplex virus encephalitis in a patient with complete TLR3 deficiency: TLR3 is otherwise redundant in protective immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Herpes simplex encephalitis in children with autosomal recessive and dominant TRIF deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Human TRAF3 adaptor molecule deficiency leads to impaired Toll-like receptor 3 response and susceptibility to herpes simplex encephalitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Heterozygous TBK1 mutations impair TLR3 immunity and underlie herpes simplex encephalitis of childhood

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

NEMO is a key component of NF-κB- and IRF-3-dependent TLR3-mediated immunity to herpes simplex virus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Primary immunodeficiencies: a field in its infancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Functional IRF3 deficiency in a patient with herpes simplex encephalitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

A protein tyrosine kinase in the interferon alpha/beta signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Human tyrosine kinase 2 deficiency reveals its requisite roles in multiple cytokine signals involved in innate and acquired immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

A patient with tyrosine kinase 2 deficiency without hyper-IgE syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Human TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Pathogen recognition and inflammatory signaling in innate immune defenses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Essential role of IPS-1 in innate immune responses against RNA viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

VISA is an adapter protein required for virus-triggered IFN-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Guidelines for genetic studies in single patients: lessons from primary immunodeficiencies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Impaired response to interferon-alpha/beta and lethal viral disease in human STAT1 deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Dominant gain-of-function STAT1 mutations in FOXP3 wild-type immune dysregulation-polyendocrinopathy-enteropathy-X-linked-like syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

STAT1 mutations in autosomal dominant chronic mucocutaneous candidiasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Innate antiviral signalling in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Age-dependent Mendelian predisposition to herpes simplex virus type 1 encephalitis in childhood

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

TLR3 deficiency in herpes simplex encephalitis: high allelic heterogeneity and recurrence risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Cell type-dependent requirement of autophagy in HSV-1 antiviral defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Immunodeficiency mutation databases (IDbases).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

KEGG: kyoto encyclopedia of genes and genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Data, information, knowledge and principle: back to metabolism in KEGG

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

A general framework for estimating the relative pathogenicity of human genetic variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2015.46

Impaired intrinsic immunity to HSV-1 in human iPSC-derived TLR3-deficient CNS cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26513235

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/GENE.2015.46

1 reference

20 September 2017

1 reference