Notch promotes survival of pre-T cells at the beta-selection checkpoint by regulating cellular metabolism (Q40390896)

20 September 2017

Notch promotes survival of pre-T cells at the beta-selection checkpoint by regulating cellular metabolism (English)

1 reference

20 September 2017

Maria Ciofani

1

0 references

author name string

Juan Carlos Zúñiga-Pflücker

series ordinal

2

1 reference

PubMed ID

16056227

20 September 2017

language of work or name

English

0 references

publication date

31 July 2005

1 reference

20 September 2017

1 reference

20 September 2017

6

1 reference

20 September 2017

881-888

1 reference

20 September 2017

9

1 reference

Regulation of thymocyte differentiation: pre-TCR signals and beta-selection

20 September 2017

1 reference

Thymus-derived signals regulate early T-cell development

21 January 2018

1 reference

The protein kinase B/Akt signalling pathway in human malignancy

21 January 2018

1 reference

Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase

21 January 2018

1 reference

Akt and Bcl-xL promote growth factor-independent survival through distinct effects on mitochondrial physiology

21 January 2018

1 reference

Akt-Directed Glucose Metabolism Can Prevent Bax Conformation Change and Promote Growth Factor-Independent Survival

21 January 2018

1 reference

Maintenance of T cell specification and differentiation requires recurrent notch receptor-ligand interactions

21 January 2018

1 reference

Notch regulation of lymphocyte development and function.

21 January 2018

1 reference

Regulation of lymphoid development, differentiation, and function by the Notch pathway.

21 January 2018

1 reference

Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha beta Lineage Thymocytes.

21 January 2018

1 reference

Obligatory role for cooperative signaling by pre-TCR and Notch during thymocyte differentiation

21 January 2018

1 reference

Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro.

21 January 2018

1 reference

T-cell development made simple

21 January 2018

1 reference

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

21 January 2018

1 reference

Restoration of T cell development in RAG-2-deficient mice by functional TCR transgenes.

21 January 2018

1 reference

Correlating notch signaling with thymocyte maturation

21 January 2018

1 reference

The Anti-apoptotic Effect of Notch-1 Requires p56 -dependent, Akt/PKB-mediated Signaling in T Cells

21 January 2018

1 reference

The pathophysiology of mitochondrial cell death

21 January 2018

1 reference

Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice

21 January 2018

1 reference

Growth factors can influence cell growth and survival through effects on glucose metabolism

21 January 2018

1 reference

In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size or viability

21 January 2018

1 reference

Mechanisms and consequences of activation of protein kinase B/Akt

21 January 2018

1 reference

The earliest T lineage-committed cells depend on IL-7 for Bcl-2 expression and normal cell cycle progression

21 January 2018

1 reference

The loss of PTEN allows TCR alphabeta lineage thymocytes to bypass IL-7 and Pre-TCR-mediated signaling

21 January 2018

1 reference

FADD/MORT1 regulates the pre-TCR checkpoint and can function as a tumour suppressor

21 January 2018

1 reference

p53 prevents maturation to the CD4+CD8+ stage of thymocyte differentiation in the absence of T cell receptor rearrangement.

21 January 2018

1 reference

IL-7 enhances the survival and maintains the size of naive T cells

21 January 2018

1 reference

Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake

21 January 2018

1 reference

Notch 1 signaling regulates peripheral T cell activation

21 January 2018

1 reference

In vitro evidence that cytokine receptor signals are required for differentiation of double positive thymocytes into functionally mature CD8+ T cells

21 January 2018

1 reference

The CD28 signaling pathway regulates glucose metabolism

21 January 2018

1 reference

Notch-induced E2A ubiquitination and degradation are controlled by MAP kinase activities

21 January 2018

1 reference

Pre-TCR-triggered ERK signalling-dependent downregulation of E2A activity in Notch3-induced T-cell lymphoma

21 January 2018

1 reference

E2A proteins enforce a proliferation checkpoint in developing thymocytes

21 January 2018

1 reference

Requirement for cyclin D3 in lymphocyte development and T cell leukemias

21 January 2018

1 reference

Notch and T cell malignancy.

21 January 2018

1 reference

Tumor induction by an Lck-MyrAkt transgene is delayed by mechanisms controlling the size of the thymus

21 January 2018

1 reference

Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis

21 January 2018

1 reference

Separation of Notch1 promoted lineage commitment and expansion/transformation in developing T cells

21 January 2018

1 reference

The pentose cycle and insulin release in mouse pancreatic islets

21 January 2018

1 reference

Flow cytometry detection of caspase 3 activation in preapoptotic leukemic cells

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Distinct roles of the phosphatidylinositol 3-kinase and STAT5 pathways in IL-7-mediated development of human thymocyte precursors

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NI1234

1 reference

20 September 2017

1 reference

PubMed ID

16056227