Nitric oxide and its role in the cardiovascular system (Q40418256)

20 September 2017

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title

Nitric oxide and its role in the cardiovascular system (English)

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20 September 2017

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Loscalzo J

1

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PubMed ID

7568906

20 September 2017

Welch G

series ordinal

2

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20 September 2017

1 September 1995

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Progress in Cardiovascular Diseases

20 September 2017

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20 September 2017

38

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20 September 2017

2

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20 September 2017

87-104

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Vascular endothelial cells synthesize nitric oxide from L-arginine

20 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Nitric oxide as a secretory product of mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

FAD and GSH participate in macrophage synthesis of nitric oxide

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Nitric oxide synthase is a cytochrome P-450 type hemoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Molecular mechanisms of nitric oxide regulation. Potential relevance to cardiovascular disease

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Calcium-dependent nitric oxide synthesis in endothelial cytosol is mediated by calmodulin

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Biosynthesis of endothelium-derived relaxing factor: a cytosolic enzyme in porcine aortic endothelial cells Ca2+-dependently converts L-arginine into an activator of soluble guanylyl cyclase

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Biological actions and properties of endothelium-derived nitric oxide formed and released from artery and vein

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediate

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Role of nitric oxide synthesis in macrophage antimicrobial activity

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Calmodulin is a subunit of nitric oxide synthase from macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Platelet-derived growth factor B chain promoter contains a cis-acting fluid shear-stress-responsive element.

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Molecular cloning and characterization of the constitutive bovine aortic endothelial cell nitric oxide synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Tetrahydrobiopterin-dependent formation of nitrite and nitrate in murine fibroblasts.

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Regulation of nitric oxide synthesis by proinflammatory cytokines in human umbilical vein endothelial cells. Elevations in tetrahydrobiopterin levels enhance endothelial nitric oxide synthase specific activity

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Biochemistry of Nitric Oxide and Its Redox-Activated Forms

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

S-nitrosylation of proteins with nitric oxide: synthesis and characterization of biologically active compounds

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Nitric oxide circulates in mammalian plasma primarily as an S-nitroso adduct of serum albumin

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Endogenous nitrogen oxides and bronchodilator S-nitrosothiols in human airways

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Signal transduction mechanisms involving nitric oxide

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Vascular smooth muscle. A review of the molecular basis of contractility

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Phosphorylation of myosin light chain kinase from vascular smooth muscle by cAMP- and cGMP-dependent protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Measurement of nitric oxide in biological models.

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Quantitative and kinetic characterization of nitric oxide and EDRF released from cultured endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Comparative pharmacology of endothelium-derived relaxing factor, nitric oxide and prostacyclin in platelets

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Endothelium-derived relaxing factor from pulmonary artery and vein possesses pharmacologic and chemical properties identical to those of nitric oxide radical

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Differential selectivity of endothelium-derived relaxing factor and nitric oxide in smooth muscle

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https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Control of coronary vascular tone by nitric oxide.

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Vasorelaxant properties of the endothelium-derived relaxing factor more closely resemble S-nitrosocysteine than nitric oxide

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

N-Acetylcysteine potentiates inhibition of platelet aggregation by nitroglycerin

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

NO forms an adduct with serum albumin that has endothelium-derived relaxing factor-like properties.

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

N-acetylcysteine potentiates platelet inhibition by endothelium-derived relaxing factor.

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

In vivo transfer of nitric oxide between a plasma protein-bound reservoir and low molecular weight thiols.

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Nitric oxide: a physiologic messenger

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Role of endothelium-derived nitric oxide in the regulation of blood pressure

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Effects of endothelium-derived nitric oxide on peripheral arteriolar tone in man

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Local inhibition of converting enzyme and vascular responses to angiotensin and bradykinin in the human forearm.

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

EDRF coordinates the behaviour of vascular resistance vessels.

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Nitric oxide regulates basal systemic and pulmonary vascular resistance in healthy humans

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Control of regional blood flow by endothelium-derived nitric oxide

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Endothelium-derived relaxing factor and coronary vasospasm

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Possible origins and distribution of immunoreactive nitric oxide synthase-containing nerve fibers in cerebral arteries

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Nitric oxide from endothelium and smooth muscle modulates responses to sympathetic nerve stimulation: implications for endotoxin shock

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Nitric oxide regulates the expression of vasoconstrictors and growth factors by vascular endothelium under both normoxia and hypoxia

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Hypoxia induces endothelin gene expression and secretion in cultured human endothelium

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https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Oxygen tension regulates the expression of the platelet-derived growth factor-B chain gene in human endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Platelet-derived growth factor suppresses and fibroblast growth factor enhances cytokine-induced production of nitric oxide by cultured smooth muscle cells. Effects on cell proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Induction and potential biological relevance of a Ca(2+)-independent nitric oxide synthase in the myocardium

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Control of cardiac muscle cell function by an endogenous nitric oxide signaling system

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https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Nitric oxide synthases and cardiovascular signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Difference between endothelium-dependent relaxation in arterial and in venous coronary bypass grafts.

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

An L-arginine/nitric oxide pathway present in human platelets regulates aggregation

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Human neutrophils and mononuclear cells inhibit platelet aggregation by releasing a nitric oxide-like factor

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Modulation of human platelet adenylate cyclase by prostacyclin (PGX)

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Endogenous nitric oxide inhibits human platelet adhesion to vascular endothelium

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

The anti-aggregating properties of vascular endothelium: interactions between prostacyclin and nitric oxide

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Synergistic disaggregation of platelets by tissue-type plasminogen activator, prostaglandin E1, and nitroglycerin

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Mediators of leukocyte adhesion in rat mesenteric venules elicited by inhibition of nitric oxide synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Nitric oxide: an endogenous modulator of leukocyte adhesion

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Nitric oxide synthesis inhibition induces leukocyte adhesion via superoxide and mast cells

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Nitric oxide-generating vasodilators inhibit mitogenesis and proliferation of BALB/C 3T3 fibroblasts by a cyclic GMP-independent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

L-arginine inhibits neointimal formation following balloon injury

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Abnormal endothelium-dependent vascular relaxation in patients with essential hypertension

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Septic shock: pathogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Stimulation of the nitric oxide synthase pathway in human hepatocytes by cytokines and endotoxin

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Immediate release of a nitric oxide-like factor from bovine aortic endothelial cells by Escherichia coli lipopolysaccharide

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Purification and characterization of the cytokine-induced macrophage nitric oxide synthase: an FAD- and FMN-containing flavoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Effect of nitric oxide synthase inhibitors on hypotension in patients with septic shock

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Macrophage and endothelial cell nitric oxide synthesis: cell-type selective inhibition by NG-aminoarginine, NG-nitroarginine and NG-methylarginine

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Glucocorticoids inhibit the expression of an inducible, but not the constitutive, nitric oxide synthase in vascular endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Methylene blue reverses endotoxin-induced hypotension

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Inhibition of nitric oxide synthesis reduces the hypotension induced by bacterial lipopolysaccharides in the rat in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Endogenously synthesized nitric oxide prevents endotoxin-induced glomerular thrombosis

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Negative inotropic effects of cytokines on the heart mediated by nitric oxide

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Abnormal contractile function due to induction of nitric oxide synthesis in rat cardiac myocytes follows exposure to activated macrophage-conditioned medium

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Interleukin-6 (IL-6) as a mediator of stunned myocardium

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Can superoxide dismutase alter myocardial infarct size?

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Cardioprotective effects of authentic nitric oxide in myocardial ischemia with reperfusion

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

The effect of nitric oxide synthase inhibition on infarct volume after reversible focal cerebral ischemia in conscious rats

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Nitric oxide, an endothelial cell relaxation factor, inhibits neutrophil superoxide anion production via a direct action on the NADPH oxidase

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Impaired vasodilation of forearm resistance vessels in hypercholesterolemic humans

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Loss of selective endothelial cell vasoactive functions caused by hypercholesterolemia in pig coronary arteries

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Hypercholesterolemia causes generalized impairment of endothelium-dependent relaxation to aggregating platelets in porcine arteries.

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Correction of endothelial dysfunction in coronary microcirculation of hypercholesterolaemic patients by L-arginine

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

L-arginine improves endothelium-dependent vasodilation in hypercholesterolemic humans

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Selective attenuation of endothelium-mediated vasodilation in atherosclerotic human coronary arteries

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Impaired endothelium-dependent vasodilation in patients with insulin-dependent diabetes mellitus.

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Effect of increased availability of endothelium-derived nitric oxide precursor on endothelium-dependent vascular relaxation in normal subjects and in patients with essential hypertension.

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Antihypertensive therapy augments endothelium-dependent relaxations in coronary arteries of spontaneously hypertensive rats

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Antiplatelet and antithrombotic effects of organic nitrates

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Biochemical mechanism of organic nitrate action

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Platelets, vasoconstriction, and nitroglycerin during arterial wall injury. A new antithrombotic role for an old drug

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Nitroglycerin prolongs the bleeding time in healthy males

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Inhibition of platelet function by injectable isosorbide dinitrate

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Intravenous nitroglycerin infusion inhibits cyclic blood flow responses caused by periodic platelet thrombus formation in stenosed canine coronary arteries

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Effect of intravenous nitrates on mortality in acute myocardial infarction: an overview of the randomised trials

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Experimental arteriosclerosis. I. Fibrous plaque formation in primates, an electron microscope study

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Diminished basal nitric oxide release after myocardial ischemia and reperfusion promotes neutrophil adherence to coronary endothelium

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Antineutrophil and myocardial protecting actions of a novel nitric oxide donor after acute myocardial ischemia and reperfusion of dogs.

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Pathological implications of nitric oxide, superoxide and peroxynitrite formation

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

The effect of nitric oxide-donating vasodilators on monocyte chemotaxis and intracellular cGMP concentrations in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Inhaled nitric oxide selectively reverses human hypoxic pulmonary vasoconstriction without causing systemic vasodilation.

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Inhaled nitric oxide as a cause of selective pulmonary vasodilatation in pulmonary hypertension

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

Inhaled nitric oxide for the adult respiratory distress syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

EPR characterization of molecular targets for NO in mammalian cells and organelles

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

The role of nitric oxide in endotoxic shock: effects of NG-monomethyl-L-arginine

1 reference

https://api.crossref.org/works/10.1016%2FS0033-0620%2805%2980001-5

7 January 2021

10.1016/S0033-0620(05)80001-5

Identifiers

DOI

1 reference

20 September 2017

1 reference

PubMed ID

7568906