Intracellular allosteric antagonism of the CCR9 receptor (Q40420305)

20 September 2017

title

Intracellular allosteric antagonism of the CCR9 receptor (English)

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20 September 2017

Christine Oswald

1

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20 September 2017

Mathieu Rappas

2

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20 September 2017

James Kean

3

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20 September 2017

Andrew S Doré

4

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20 September 2017

James C Errey

5

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20 September 2017

Kirstie Bennett

6

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20 September 2017

Francesca Deflorian

7

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20 September 2017

John A Christopher

8

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20 September 2017

Ali Jazayeri

9

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20 September 2017

Jonathan S Mason

10

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20 September 2017

Miles Congreve

11

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20 September 2017

Robert M Cooke

12

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20 September 2017

Fiona H Marshall

13

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20 September 2017

language of work or name

English

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publication date

7 December 2016

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20 September 2017

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20 September 2017

volume

540

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20 September 2017

issue

7633

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20 September 2017

page(s)

462-465

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Targeting chemokine receptors in allergic disease

20 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

CCR5 antagonism in HIV infection: current concepts and future opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

Chemokine receptor-specific antibodies in cancer immunotherapy: achievements and challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

"Chemokine receptors as therapeutic targets: Why aren't there more drugs?".

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

Allosteric Modulation as a Unifying Mechanism for Receptor Function and Regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

Conformational thermostabilization of the beta1-adrenergic receptor in a detergent-resistant form

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

The properties of thermostabilised G protein-coupled receptors (StaRs) and their use in drug discovery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

Characterization of CCX282-B, an orally bioavailable antagonist of the CCR9 chemokine receptor, for treatment of inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

Structure of the CCR5 Chemokine Receptor-HIV Entry Inhibitor Maraviroc Complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

Structure of class B GPCR corticotropin-releasing factor receptor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

Extra-helical binding site of a glucagon receptor antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

Discovery of a CXCR4 agonist pepducin that mobilizes bone marrow hematopoietic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

An intracellular allosteric site for a specific class of antagonists of the CC chemokine G protein-coupled receptors CCR4 and CCR5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

Pharmacological characterization of Sch527123, a potent allosteric CXCR1/CXCR2 antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

A common intracellular allosteric binding site for antagonists of the CXCR2 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

SB-656933, a novel CXCR2 selective antagonist, inhibits ex vivo neutrophil activation and ozone-induced airway inflammation in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

Identification of a putative intracellular allosteric antagonist binding-site in the CXC chemokine receptors 1 and 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

Nonpeptidergic allosteric antagonists differentially bind to the CXCR2 chemokine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

Dancing to the tune of chemokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

Structural insights into agonist-induced activation of G-protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

Unifying family A GPCR theories of activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

Crystal structure of the β2 adrenergic receptor-Gs protein complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

Membrane protein orientation and refinement using a knowledge-based statistical potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

The MPI bioinformatics Toolkit as an integrative platform for advanced protein sequence and structure analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

Fluorescence-detection size-exclusion chromatography for precrystallization screening of integral membrane proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

Crystallizing membrane proteins using lipidic mesophases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

Integration, scaling, space-group assignment and post-refinement

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

The CCP4 suite: programs for protein crystallography

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

How good are my data and what is the resolution?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

Phasercrystallographic software

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

Features and development of Coot

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

PHENIX: a comprehensive Python-based system for macromolecular structure solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

REFMAC5 for the refinement of macromolecular crystal structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

Towards automated crystallographic structure refinement with phenix.refine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

Better models by discarding data?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE20606

CCR9 antagonism: potential in the treatment of Inflammatory Bowel Disease.

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27926729

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Chemokine receptor antagonists

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27926729

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE20606

1 reference

Dimensions Publication ID

20 September 2017

1035654649

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1 reference