Transthyretin Binding Heterogeneity and Anti-amyloidogenic Activity of Natural Polyphenols and Their Metabolites (Q40430478)

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27 February 2020

title

Transthyretin Binding Heterogeneity and Anti-amyloidogenic Activity of Natural Polyphenols and Their Metabolites (English)

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27 February 2020

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4

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27 February 2020

Michele Cianci

3

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27 February 2020

Rodolfo Berni

6

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27 February 2020

author name string

Paola Florio

1

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27 February 2020

Claudia Folli

2

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27 February 2020

Giuseppe Zanotti

5

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27 February 2020

language of work or name

English

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publication date

14 October 2015

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Journal of Biological Chemistry

27 February 2020

published in

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27 February 2020

volume

290

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27 February 2020

issue

50

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27 February 2020

page(s)

29769-29780

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Structural evidence for asymmetric ligand binding to transthyretin

27 February 2020

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22 September 2017

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Trapping of palindromic ligands within native transthyretin prevents amyloid formation

22 September 2017

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22 September 2017

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Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding

22 September 2017

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Structure-based design of kinetic stabilizers that ameliorate the transthyretin amyloidoses

22 September 2017

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22 September 2017

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Amyloidogenic Potential of Transthyretin Variants: INSIGHTS FROM STRUCTURAL AND COMPUTATIONAL ANALYSES

22 September 2017

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Quantification of the thermodynamically linked quaternary and tertiary structural stabilities of transthyretin and its disease-associated variants: the relationship between stability and amyloidosis.

22 September 2017

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The molecular biology and clinical features of amyloid neuropathy

22 September 2017

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Acidic pH-induced conformational changes in amyloidogenic mutant transthyretin

22 September 2017

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Genistein and other soya isoflavones are potent ligands for transthyretin in serum and cerebrospinal fluid

22 September 2017

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Native state kinetic stabilization as a strategy to ameliorate protein misfolding diseases: a focus on the transthyretin amyloidoses.

22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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15 June 2018

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15 June 2018

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15 June 2018

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Anti-amyloidogenic effects of soybean isoflavones in vitro: Fluorescence spectroscopy demonstrating direct binding to Aβ monomers, oligomers and fibrils

20 August 2018

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Binding and stabilization of transthyretin by curcumin.

20 August 2018

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Structures of human transthyretin complexed with thyroxine at 2.0 A resolution and 3',5'-dinitro-N-acetyl-L-thyronine at 2.2 A resolution

20 August 2018

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Native state stabilization by NSAIDs inhibits transthyretin amyloidogenesis from the most common familial disease variants

20 August 2018

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Comparative calorimetric study of non-amyloidogenic and amyloidogenic variants of the homotetrameric protein transthyretin

20 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M115.690172

21 January 2018

Identifiers

DOI

10.1074/JBC.M115.690172

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26468275%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26468275%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

PubMed publication ID

26468275

1 reference