Leptin receptor activation depends on critical cysteine residues in its fibronectin type III subdomains (Q40433191)

20 September 2017

Leptin receptor activation depends on critical cysteine residues in its fibronectin type III subdomains (English)

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20 September 2017

Lennart Zabeau

1

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20 September 2017

Delphine Defeau

2

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20 September 2017

Hannes Iserentant

3

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20 September 2017

Joël Vandekerckhove

4

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20 September 2017

Frank Peelman

5

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20 September 2017

Jan Tavernier

6

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20 September 2017

language of work or name

English

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publication date

18 April 2005

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Journal of Biological Chemistry

20 September 2017

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20 September 2017

280

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20 September 2017

24

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20 September 2017

22632-22640

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Serum immunoreactive-leptin concentrations in normal-weight and obese humans

20 September 2017

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https://api.crossref.org/works/10.1074%2FJBC.M413308200

Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413308200

Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413308200

Weight-reducing effects of the plasma protein encoded by the obese gene

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M413308200

Effects of the obese gene product on body weight regulation in ob/ob mice

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M413308200

Congenital leptin deficiency is associated with severe early-onset obesity in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413308200

Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M413308200

A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413308200

Abnormal splicing of the leptin receptor in diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413308200

Regulation of metabolism and body fat mass by leptin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413308200

Identification and expression cloning of a leptin receptor, OB-R

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413308200

Functional Analysis of Leptin Receptor Activation Using a Janus Kinase/Signal Transducer and Activator of Transcription Complementation Assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413308200

Ligand-independent dimerization of the extracellular domain of the leptin receptor and determination of the stoichiometry of leptin binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413308200

Activation of the Leptin Receptor by a Ligand-induced Conformational Change of Constitutive Receptor Dimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413308200

Mapping of the leptin binding sites and design of a leptin antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413308200

Identification of the Y985 and Y1077 motifs as SOCS3 recruitment sites in the murine leptin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413308200

Human leptin receptor. Determination of disulfide structure and N-glycosylation sites of the extracellular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413308200

Crystallographic evidence for preformed dimers of erythropoietin receptor before ligand activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413308200

Seeing the light: preassembly and ligand-induced changes of the interferon gamma receptor complex in cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413308200

The human interleukin-6 (IL-6) receptor exists as a preformed dimer in the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413308200

Structure of the complete extracellular domain of the common beta subunit of the human GM-CSF, IL-3, and IL-5 receptors reveals a novel dimer configuration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413308200

Subcloning, expression, purification, and characterization of recombinant human leptin-binding domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413308200

Human interleukin-3 (IL-3) induces disulfide-linked IL-3 receptor alpha- and beta-chain heterodimerization, which is required for receptor activation but not high-affinity binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413308200

Identification of a Cys motif in the common beta chain of the interleukin 3, granulocyte-macrophage colony-stimulating factor, and interleukin 5 receptors essential for disulfide-linked receptor heterodimerization and activation of all three recepto

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413308200

Signal transducer gp130: biochemical characterization of the three membrane-proximal extracellular domains and evaluation of their oligomerization potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413308200

Hexameric structure and assembly of the interleukin-6/IL-6 alpha-receptor/gp130 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413308200

Low levels of expression of leptin receptor at the cell surface result from constitutive endocytosis and intracellular retention in the biosynthetic pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M413308200

21 January 2018

Identifiers

DOI

10.1074/JBC.M413308200

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20 September 2017

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