Epidermal growth factor receptor coexpression modulates susceptibility to Herceptin in HER2/neu overexpressing breast cancer cells via specific erbB-receptor interaction and activation. (Q40450413)

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scientific article published on 21 January 2005

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English	Epidermal growth factor receptor coexpression modulates susceptibility to Herceptin in HER2/neu overexpressing breast cancer cells via specific erbB-receptor interaction and activation.	scientific article published on 21 January 2005

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scholarly article

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Europe PubMed Central

20 September 2017

Epidermal growth factor receptor coexpression modulates susceptibility to Herceptin in HER2/neu overexpressing breast cancer cells via specific erbB-receptor interaction and activation. (English)

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Europe PubMed Central

20 September 2017

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Ruth Knüchel-Clarke

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object named as

Ruth Knuechel-Clarke

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Europe PubMed Central

20 September 2017

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Gero Brockhoff

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author name string

Simone Diermeier

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Europe PubMed Central

20 September 2017

Gábor Horváth

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Europe PubMed Central

20 September 2017

Ferdinand Hofstaedter

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Europe PubMed Central

20 September 2017

János Szöllosi

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Europe PubMed Central

20 September 2017

Gero Brockhoff

6

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Europe PubMed Central

20 September 2017

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21 January 2005

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20 September 2017

Experimental Cell Research

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304

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604-619

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Europe PubMed Central

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Europe PubMed Central

20 September 2017

Rationale for trastuzumab (Herceptin) in adjuvant breast cancer trials

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Evaluation of HER-2/neu gene amplification and overexpression: comparison of frequently used assay methods in a molecularly characterized cohort of breast cancer specimens.

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Evaluating HER2 amplification and overexpression in breast cancer.

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The molecular and cellular biology of HER2/neu gene amplification/overexpression and the clinical development of herceptin (trastuzumab) therapy for breast cancer.

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Antibodies as molecular target-based therapy: trastuzumab

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Biology of HER2 and its importance in breast cancer

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Untangling the ErbB signalling network

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Complexity of signal transduction mediated by ErbB2: clues to the potential of receptor-targeted cancer therapy.

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Small interfering RNAs suppress the expression of endogenous and GFP-fused epidermal growth factor receptor (erbB1) and induce apoptosis in erbB1-overexpressing cells

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Cooperative inhibitory effect of ZD1839 (Iressa) in combination with trastuzumab (Herceptin) on human breast cancer cell growth.

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Rational combinations of trastuzumab with chemotherapeutic drugs used in the treatment of breast cancer

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The EGF receptor family as targets for cancer therapy

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The ErbB signaling network: receptor heterodimerization in development and cancer

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Overexpression of the EGF receptor-related proto-oncogene erbB-2 in human mammary tumor cell lines by different molecular mechanisms

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Epidermal growth factor receptor, c-erbB2 and c-erbB3 receptor interaction, and related cell cycle kinetics of SK-BR-3 and BT474 breast carcinoma cells

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EGF-induced redistribution of erbB2 on breast tumor cells: flow and image cytometric energy transfer measurements.

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Long wavelength fluorophores and cell-by-cell correction for autofluorescence significantly improves the accuracy of flow cytometric energy transfer measurements on a dual-laser benchtop flow cytometer.

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Exposure to continuous bromodeoxyuridine (BrdU) differentially affects cell cycle progression of human breast and bladder cancer cell lines

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ErbB2 potentiates breast tumor proliferation through modulation of p27(Kip1)-Cdk2 complex formation: receptor overexpression does not determine growth dependency

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EGF induces cell cycle arrest of A431 human epidermoid carcinoma cells

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Evaluation of novel epidermal growth factor receptor tyrosine kinase inhibitors

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MDA-468, a human breast cancer cell line with a high number of epidermal growth factor (EGF) receptors, has an amplified EGF receptor gene and is growth inhibited by EGF.

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Ligand-induced, p38-dependent apoptosis in cells expressing high levels of epidermal growth factor receptor and ErbB-2.

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Constitutive activation of the neuregulin-1/erbB signaling pathway promotes the proliferation of a human peripheral neuroepithelioma cell line.

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The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation

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Cbl-b-dependent coordinated degradation of the epidermal growth factor receptor signaling complex

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Mechanism of action of anti-HER2 monoclonal antibodies: scientific update on trastuzumab and 2C4

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A new therapeutic antibody masks ErbB2 to its partners

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PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients.

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Signal transduction and oncogenesis by ErbB/HER receptors

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The FUTURE of ErbB-1 and ErbB-2 pathway inhibition in breast cancer: targeting multiple receptors

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A Phase I/II Trial of trastuzumab and gefitinib in patients with Metastatic Breast Cancer that overexpresses HER2/neu (ErbB-2).

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Target-based agents against ErbB receptors and their ligands: a novel approach to cancer treatment

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Is there a role for epidermal growth factor receptor inhibitors in breast cancer prevention?

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Augmentation of a humanized anti-HER2 mAb 4D5 induced growth inhibition by a human-mouse chimeric anti-EGF receptor mAb C225

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Prognostic value of the combination of epidermal growth factor receptor and c-erbB-2 in breast cancer

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Identifiers

10.1016/J.YEXCR.2004.12.008

1 reference

Europe PubMed Central

20 September 2017

1 reference

Europe PubMed Central

20 September 2017

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