Growth hormone receptor is a target for presenilin-dependent gamma-secretase cleavage. (Q40451732)

20 September 2017

Growth hormone receptor is a target for presenilin-dependent gamma-secretase cleavage. (English)

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20 September 2017

9

Stuart J Frank

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20 September 2017

Jon W Cowan

1

1 reference

20 September 2017

Xiangdong Wang

2

1 reference

20 September 2017

Ran Guan

3

1 reference

20 September 2017

Kai He

4

1 reference

20 September 2017

Jing Jiang

5

1 reference

20 September 2017

Gerhard Baumann

6

1 reference

20 September 2017

Roy A Black

7

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20 September 2017

Michael S Wolfe

8

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20 September 2017

language of work or name

English

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publication date

2 March 2005

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Journal of Biological Chemistry

20 September 2017

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20 September 2017

280

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20 September 2017

19

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20 September 2017

19331-19342

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The spectrum of growth-hormone insensitivity

20 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Molecular mechanism of growth hormone action

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Regions of the JAK2 tyrosine kinase required for coupling to the growth hormone receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

The conserved box 1 motif of cytokine receptors is required for association with JAK kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Blockade of growth hormone receptor shedding by a metalloprotease inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Phorbol ester- and growth factor-induced growth hormone (GH) receptor proteolysis and GH-binding protein shedding: relationship to GH receptor down-regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Growth hormone (GH)-induced dimerization inhibits phorbol ester-stimulated GH receptor proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Metalloprotease-mediated GH receptor proteolysis and GHBP shedding. Determination of extracellular domain stem region cleavage site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Reduced proteolysis of rabbit growth hormone (GH) receptor substituted with mouse GH receptor cleavage site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

A portrait of Alzheimer secretases--new features and familiar faces

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

ErbB-4: mechanism of action and biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Regulated intramembrane proteolysis of the p75 neurotrophin receptor modulates its association with the TrkA receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Presenilin-dependent gamma-secretase-like intramembrane cleavage of ErbB4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

gamma -Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

The ERBB4/HER4 receptor tyrosine kinase regulates gene expression by functioning as a STAT5A nuclear chaperone

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Release of a membrane-bound death domain by gamma-secretase processing of the p75NTR homolog NRADD

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Intramembrane proteolysis: theme and variations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Reconstitution of gamma-secretase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Protection against a lethal dose of endotoxin by an inhibitor of tumour necrosis factor processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Demonstration of direct effects of growth hormone on neonatal cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Spontaneous heritable changes leading to increased adipose conversion in 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Total inactivation of gamma-secretase activity in presenilin-deficient embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

A conformationally sensitive GHR [growth hormone (GH) receptor] antibody: impact on GH signaling and GHR proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Microarray analyses identify JAK2 tyrosine kinase as a key mediator of ligand-independent gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Disulfide linkage of growth hormone (GH) receptors (GHR) reflects GH-induced GHR dimerization. Association of JAK2 with the GHR is enhanced by receptor dimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Identification of a novel ubiquitin conjugation motif, required for ligand-induced internalization of the growth hormone receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Growth hormone receptor and serum binding protein: purification, cloning and expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Growth hormone-dependent tyrosine phosphorylation of a GH receptor-associated high molecular WEIGHT protein immunologically related to JAK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

The signal transduction of the growth hormone receptor is regulated by the ubiquitin/proteasome system and continues after endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

c-Cbl is a negative regulator of GH-stimulated STAT5-mediated transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

The ubiquitin-proteasome pathway regulates the availability of the GH receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

The ubiquitin-proteasome pathway and the regulation of growth hormone receptor availability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Jak2 and proteasome activities control the availability of cell surface growth hormone receptors during ligand exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Proteasome inhibitor enhances growth hormone-binding protein release

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Proteasomes are involved in the constitutive degradation of growth hormone receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Termination of growth hormone pulse-induced STAT5b signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Growth hormone-dependent differentiation of 3T3-F442A preadipocytes requires Janus kinase/signal transducer and activator of transcription but not mitogen-activated protein kinase or p70 S6 kinase signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Growth hormone-induced alteration in ErbB-2 phosphorylation status in 3T3-F442A fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Involvement of the Src homology 2-containing tyrosine phosphatase SHP-2 in growth hormone signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

A role for Grb2-associated binder-1 in growth hormone signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Janus kinase 2 determinants for growth hormone receptor association, surface assembly, and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Intracellular maturation and localization of the tumour necrosis factor alpha convertase (TACE)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Calpain inhibitor I increases beta-amyloid peptide production by inhibiting the degradation of the substrate of gamma-secretase. Evidence that substrate availability limits beta-amyloid peptide production

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

A RIP tide in neuronal signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Presenilins mutated at Asp-257 or Asp-385 restore Pen-2 expression and Nicastrin glycosylation but remain catalytically inactive in the absence of wild type Presenilin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

The intracellular domain of the low density lipoprotein receptor-related protein modulates transactivation mediated by amyloid precursor protein and Fe65.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Proteolytic release of CD44 intracellular domain and its role in the CD44 signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Presenilin-dependent gamma-secretase activity mediates the intramembranous cleavage of CD44.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Proteolytic processing of low density lipoprotein receptor-related protein mediates regulated release of its intracellular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Monkey growth hormone (GH) receptor gene expression. Evidence for two mechanisms for the generation of the GH binding protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Water-Soluble Specific Growth Hormone Binding Sites from Cultured Human Lymphocytes: Preparation and Partial Characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Release of growth hormone binding protein from IM-9 lymphocytes by endopeptidase is dependent on sulfhydryl group inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Regulation of human growth hormone-binding protein production by human growth hormone in a hepatoma cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Shedding of growth hormone-binding protein is inhibited by hydroxamic acid-based protease inhibitors: proposed mechanism of activation of growth hormone-binding protein secretase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

A method to increase the number of growth hormone receptors at the surface of cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

The amyloid precursor protein (APP)-cytoplasmic fragment generated by gamma-secretase is rapidly degraded but distributes partially in a nuclear fraction of neurones in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Gamma-secretase: proteasome of the membrane?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Grb10 identified as a potential regulator of growth hormone (GH) signaling by cloning of GH receptor target proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

Heregulin-dependent Trafficking and Cleavage of ErbB-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500621200

21 January 2018

Identifiers

DOI

10.1074/JBC.M500621200

1 reference

20 September 2017

1 reference