Novel pantothenate derivatives for anti-malarial chemotherapy (Q40484106)

20 September 2017

Novel pantothenate derivatives for anti-malarial chemotherapy (English)

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Marga van de Vegte-Bolmer

20 September 2017

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object named as

Marga van de Vegte-Bolmer

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20 September 2017

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Robert W Sauerwein

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20 September 2017

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Koen J Dechering

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20 September 2017

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Karin M J Koolen

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20 September 2017

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Wouter Graumans

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20 September 2017

Helmi E Pett

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20 September 2017

Patrick A M Jansen

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20 September 2017

Pedro H H Hermkens

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20 September 2017

Peter N M Botman

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20 September 2017

Christien A Beuckens-Schortinghuis

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20 September 2017

Richard H Blaauw

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20 September 2017

Floris P J T Rutjes

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20 September 2017

Joost Schalkwijk

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20 September 2017

18 April 2015

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169

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Creative Commons Attribution 4.0 International

20 September 2017

start time

18 April 2015

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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exact match

https://scigraph.springernature.com/pub.10.1186/s12936-015-0673-8

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cites work

Structural modification of pantothenamides counteracts degradation by pantetheinase and improves antiplasmodial activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425855

Designing the next generation of medicines for malaria control and eradication

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425855

Identification and functional analysis of the primary pantothenate transporter, PfPAT, of the human malaria parasite Plasmodium falciparum

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425855

Pantothenamides are potent, on-target inhibitors of Plasmodium falciparum growth when serum pantetheinase is inactivated

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425855

Discovery of small molecule vanin inhibitors: new tools to study metabolism and disease.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425855

The antibiotic CJ-15,801 is an antimetabolite that hijacks and then inhibits CoA biosynthesis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425855

A fluorescent assay suitable for inhibitor screening and vanin tissue quantification

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425855

Coenzyme A biosynthesis: an antimicrobial drug target

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425855

Taking the time to study competitive antagonism

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425855

Provitamin B5 (pantothenol) inhibits growth of the intraerythrocytic malaria parasite

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425855

Human malaria parasites in continuous culture

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425855

Novel, rapid, and inexpensive cell-based quantification of antimalarial drug efficacy.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425855

Simple and inexpensive fluorescence-based technique for high-throughput antimalarial drug screening.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425855

Combination of pantothenamides with vanin inhibitors as a novel antibiotic strategy against gram-positive bacteria.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425855

The antibiotic activity of N-pentylpantothenamide results from its conversion to ethyldethia-coenzyme a, a coenzyme a antimetabolite

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425855

Further Studies on the Effects of Antipantothenates on Malaria Parasites (Plasmodium coatneyiandP. falciparum)in vitro*

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425855

Nutritional requirements of Plasmodium falciparum in culture. I. Exogenously supplied dialyzable components necessary for continuous growth

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425855

CJ-15,801, a fungal natural product, inhibits the intraerythrocytic stage of Plasmodium falciparum in vitro via an effect on pantothenic acid utilisation

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425855

Acyl carrier protein is a cellular target for the antibacterial action of the pantothenamide class of pantothenate antimetabolites

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425855

Coenzyme A and the antimalarial action in vitro of antipantothenate against Plasmodium lophurae, P. coatneyi and P. falciparum

20 August 2018

1 reference

12 December 2020

Studies in chemotherapy; amides of pantoyltaurine

1 reference

12 December 2020

N1-(substituted) pantothenamides, antimetabolites of pantothenic acid

1 reference

12 December 2020

Synchronization of Plasmodium falciparum gametocytes using an automated suspension culture system

1 reference

12 December 2020

10.1186/S12936-015-0673-8

Identifiers

DOI

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Dimensions Publication ID

20 September 2017

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/s12936-015-0673-8

1 reference

20 September 2017

PubMed publication ID

25927675

1 reference