The BRCA1 RING and BRCT domains cooperate in targeting BRCA1 to ionizing radiation-induced nuclear foci (Q40486944)

21 September 2017

title

The BRCA1 RING and BRCT domains cooperate in targeting BRCA1 to ionizing radiation-induced nuclear foci (English)

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21 September 2017

Wendy W Y Au

1

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21 September 2017

Beric R Henderson

series ordinal

2

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21 September 2017

language of work or name

English

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publication date

29 November 2004

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Journal of Biological Chemistry

21 September 2017

published in

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21 September 2017

volume

280

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21 September 2017

issue

8

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21 September 2017

page(s)

6993-7001

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DNA double-strand breaks: signaling, repair and the cancer connection

21 September 2017

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The BRCT Domain Is a Phospho-Protein Binding Domain

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Phosphopeptide Binding Specificities of BRCA1 COOH-terminal (BRCT) Domains

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The second BRCT domain of BRCA1 proteins interacts with p53 and stimulates transcription from the p21WAF1/CIP1 promoter

21 January 2018

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Binding of CtIP to the BRCT repeats of BRCA1 involved in the transcription regulation of p21 is disrupted upon DNA damage

21 January 2018

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BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function

21 January 2018

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Characterization of a carboxy-terminal BRCA1 interacting protein

21 January 2018

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BRCA1 transcriptionally regulates genes involved in breast tumorigenesis

21 January 2018

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21 January 2018

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21 January 2018

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Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX

21 January 2018

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BARD1 induces BRCA1 intranuclear foci formation by increasing RING-dependent BRCA1 nuclear import and inhibiting BRCA1 nuclear export

21 January 2018

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21 January 2018

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Impaired DNA damage response in cells expressing an exon 11-deleted murine Brca1 variant that localizes to nuclear foci

21 January 2018

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Identification of a functional nuclear export sequence in BRCA1.

21 January 2018

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MDC1 is required for the intra-S-phase DNA damage checkpoint

21 January 2018

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21 January 2018

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21 January 2018

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BARD1 regulates BRCA1 apoptotic function by a mechanism involving nuclear retention

21 January 2018

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The nuclear localization sequences of the BRCA1 protein interact with the importin-alpha subunit of the nuclear transport signal receptor

21 January 2018

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BRCA1 is associated with the centrosome during mitosis.

21 January 2018

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Control of biochemical reactions through supramolecular RING domain self-assembly

21 January 2018

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Nibrin forkhead-associated domain and breast cancer C-terminal domain are both required for nuclear focus formation and phosphorylation

21 January 2018

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Crystal structure of the BRCT repeat region from the breast cancer-associated protein BRCA1

21 January 2018

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Structural consequences of a cancer-causing BRCA1-BRCT missense mutation

21 January 2018

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Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer

21 January 2018

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Structure of the BRCT Repeats of BRCA1 Bound to a BACH1 Phosphopeptide

21 January 2018

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Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks

21 January 2018

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Mediator of DNA damage checkpoint protein 1 regulates BRCA1 localization and phosphorylation in DNA damage checkpoint control

21 January 2018

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A DNA damage-regulated BRCT-containing protein, TopBP1, is required for cell survival

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M408879200

1 reference

21 September 2017

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