The pancreatic duodenal homeobox-1 protein (Pdx-1) interacts with histone deacetylases Hdac-1 and Hdac-2 on low levels of glucose (Q40501718)

21 September 2017

The pancreatic duodenal homeobox-1 protein (Pdx-1) interacts with histone deacetylases Hdac-1 and Hdac-2 on low levels of glucose (English)

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21 September 2017

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Amber L Mosley

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21 September 2017

Sabire Ozcan

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PubMed ID

15496408

21 September 2017

language of work or name

English

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publication date

20 October 2004

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Journal of Biological Chemistry

21 September 2017

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21 September 2017

279

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21 September 2017

54241-54247

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21 September 2017

52

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Transcription factors in islet development and physiology: role of PDX-1 in beta-cell function

21 September 2017

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https://api.crossref.org/works/10.1074%2FJBC.M410379200

Control of insulin gene expression by glucose

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M410379200

Regulation of insulin gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410379200

Glucose-induced transcription of the insulin gene is mediated by factors required for beta-cell-type-specific expression

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M410379200

Factors controlling pancreatic cell differentiation and function.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M410379200

Pancreatic duodenal homeobox-1, PDX-1, a major regulator of beta cell identity and function.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M410379200

Pancreas duodenum homeobox-1 regulates pancreas development during embryogenesis and islet cell function in adulthood

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410379200

Glucose modulation of insulin mRNA levels is dependent on transcription factor PDX-1 and occurs independently of changes in intracellular Ca2+.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410379200

Defective glucose-regulated insulin gene expression associated with PDX-1 deficiency in the Psammomys obesus model of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410379200

Insulin promoter factor-1 gene mutation linked to early-onset type 2 diabetes mellitus directs expression of a dominant negative isoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410379200

The language of covalent histone modifications

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M410379200

Histone modifications in transcriptional regulation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M410379200

Histone deacetylases: silencers for hire.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M410379200

Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410379200

The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M410379200

Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410379200

Functional characterization of an amino-terminal region of HDAC4 that possesses MEF2 binding and transcriptional repressive activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410379200

Histone deacetylases, transcriptional control, and cancer

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M410379200

A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410379200

Phosphatase inhibition leads to histone deacetylases 1 and 2 phosphorylation and disruption of corepressor interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410379200

SUMO-1 modification of histone deacetylase 1 (HDAC1) modulates its biological activities

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M410379200

Pbx-Hox heterodimers recruit coactivator-corepressor complexes in an isoform-specific manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410379200

Insulin gene transcription is mediated by interactions between the p300 coactivator and PDX-1, BETA2, and E47.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410379200

Glucose regulation of insulin gene expression requires the recruitment of p300 by the beta-cell-specific transcription factor Pdx-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410379200

Glucose regulates insulin gene transcription by hyperacetylation of histone h4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410379200

Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410379200

Characterizing transcription factor binding sites using formaldehyde crosslinking and immunoprecipitation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410379200

Quantitative assessment of gene targeting in vitro and in vivo by the pancreatic transcription factor, Pdx1. Importance of chromatin structure in directing promoter binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410379200

Quantitative analysis of the hormone-induced hyperacetylation of histone H3 associated with the steroidogenic acute regulatory protein gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410379200

Isolation and characterization of cDNAs corresponding to an additional member of the human histone deacetylase gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410379200

A simplified system for generating recombinant adenoviruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410379200

A microplate reader-based nonisotopic histone deacetylase activity assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410379200

Glucose-dependent translocation of insulin promoter factor-1 (IPF-1) between the nuclear periphery and the nucleoplasm of single MIN6 beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410379200

Phosphorylation-dependent nucleocytoplasmic shuttling of pancreatic duodenal homeobox-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410379200

Crystal structure of the tumor-promoter okadaic acid bound to protein phosphatase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410379200

Differential roles of p300 and PCAF acetyltransferases in muscle differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410379200

Attenuation of a phosphorylation-dependent activator by an HDAC-PP1 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410379200

Phosphorylated CREB binds specifically to the nuclear protein CBP

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M410379200

Nuclear protein CBP is a coactivator for the transcription factor CREB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410379200

Identification of PCIF1, a POZ domain protein that inhibits PDX-1 (MODY4) transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410379200

Regulation of histone deacetylase 2 by protein kinase CK2.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M410379200

Histone deacetylase 1 phosphorylation promotes enzymatic activity and complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410379200

21 January 2018

Identifiers

DOI

10.1074/JBC.M410379200

1 reference

21 September 2017

1 reference

PubMed ID

15496408