Glucose regulates insulin gene transcription by hyperacetylation of histone h4. (Q40660400)

22 September 2017

Glucose regulates insulin gene transcription by hyperacetylation of histone h4. (English)

1 reference

22 September 2017

1 reference

1

Amber L Mosley

1 reference

22 September 2017

Sabire Ozcan

2

1 reference

PubMed ID

12665509

22 September 2017

language of work or name

English

0 references

publication date

28 March 2003

1 reference

Journal of Biological Chemistry

22 September 2017

1 reference

22 September 2017

278

1 reference

22 September 2017

19660-19666

1 reference

22 September 2017

22

1 reference

Metabolic coupling factors in pancreatic beta-cell signal transduction

22 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Diabetic hyperglycemia: link to impaired glucose transport in pancreatic beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Reduction in pancreatic transcription factor PDX-1 impairs glucose-stimulated insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Selective insulin signaling through A and B insulin receptors regulates transcription of insulin and glucokinase genes in pancreatic beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Regulation of gene expression by glucose in pancreatic beta -cells (MIN6) via insulin secretion and activation of phosphatidylinositol 3'-kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Profound defects in pancreatic beta-cell function in mice with combined heterozygous mutations in Pdx-1, Hnf-1alpha, and Hnf-3beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Regulation of insulin gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

The insulin gene contains multiple transcriptional elements that respond to glucose

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Transcriptional regulation of the human insulin gene is dependent on the homeodomain protein STF1/IPF1 acting through the CT boxes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Glucose modulates the binding of an islet-specific factor to a conserved sequence within the rat I and the human insulin promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Glucose-induced transcription of the insulin gene is mediated by factors required for beta-cell-type-specific expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

The role of the insulin control element and RIPE3b1 activators in glucose-stimulated transcription of the insulin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

A novel glucose-responsive element in the human insulin gene functions uniquely in primary cultured islets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

The NeuroD1/BETA2 sequences essential for insulin gene transcription colocalize with those necessary for neurogenesis and p300/CREB binding protein binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

The homeodomain protein IPF-1/STF-1 is expressed in a subset of islet cells and promotes rat insulin 1 gene expression dependent on an intact E1 helix-loop-helix factor binding site.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

The RIPE3b1 activator of the insulin gene is composed of a protein(s) of approximately 43 kDa, whose DNA binding activity is inhibited by protein phosphatase treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Identification of beta-cell-specific insulin gene transcription factor RIPE3b1 as mammalian MafA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

PDX:PBX complexes are required for normal proliferation of pancreatic cells during development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

The homeodomain of PDX-1 mediates multiple protein-protein interactions in the formation of a transcriptional activation complex on the insulin promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Insulin gene transcription is mediated by interactions between the p300 coactivator and PDX-1, BETA2, and E47.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Altered expression of HES-1, BETA2/NeuroD, and PDX-1 is involved in impaired insulin synthesis induced by glucocorticoids in HIT-T15 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Histone modifications in transcriptional regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Signaling to chromatin through histone modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Direct examination of histone acetylation on Myc target genes using chromatin immunoprecipitation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Modifying gene expression programs by altering core promoter chromatin architecture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Acetylation and chromosomal functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Acetylation of histones and transcription-related factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Special HATs for special occasions: linking histone acetylation to chromatin assembly and gene activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Histone acetyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Rapid histone H3 phosphorylation in response to growth factors, phorbol esters, okadaic acid, and protein synthesis inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Regulation of chromatin structure by site-specific histone H3 methyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

21 January 2018

Decoding the nucleosome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

p300 mediates transcriptional stimulation by the basic helix-loop-helix activators of the insulin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Differential expression of insulin genes 1 and 2 in MIN6 cells and pseudoislets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Expression of genes for alcohol and aldehyde metabolizing enzymes in mouse oocytes and preimplantation embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Characterizing transcription factor binding sites using formaldehyde crosslinking and immunoprecipitation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

c-Myc target gene specificity is determined by a post-DNAbinding mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Quantitative assessment of gene targeting in vitro and in vivo by the pancreatic transcription factor, Pdx1. Importance of chromatin structure in directing promoter binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Glucose stimulates translocation of the homeodomain transcription factor PDX1 from the cytoplasm to the nucleus in pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Glucose modulation of insulin mRNA levels is dependent on transcription factor PDX-1 and occurs independently of changes in intracellular Ca2+.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Sodium butyrate inhibits histone deacetylation in cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Binding of c-Myc to chromatin mediates mitogen-induced acetylation of histone H4 and gene activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Hepatic nuclear factor 1-alpha directs nucleosomal hyperacetylation to its tissue-specific transcriptional targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Loss of HNF-1alpha function in mice leads to abnormal expression of genes involved in pancreatic islet development and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Transcriptional activation by hepatocyte nuclear factor-1 requires synergism between multiple coactivator proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Transcriptional activation of the GLUT2 gene by the IPF-1/STF-1/IDX-1 homeobox factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Ordered recruitment of chromatin modifying and general transcription factors to the IFN-beta promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Virus infection leads to localized hyperacetylation of histones H3 and H4 at the IFN-beta promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Class I histone deacetylases sequentially interact with MyoD and pRb during skeletal myogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

p300 is required for MyoD-dependent cell cycle arrest and muscle-specific gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Coordination of a transcriptional switch by HMGI(Y) acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

Physiology meets biophysics: visualizing the interaction of hypoxia-inducible factor 1 alpha with p300 and CBP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

The loss of GLUT2 expression in the pancreatic β-cells of diabetic db/db mice is associated with an impaired DNA-binding activity of islet-specific trans-acting factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212375200

21 January 2018

Identifiers

DOI

10.1074/JBC.M212375200

1 reference

22 September 2017

1 reference

PubMed ID

12665509