Glucose-stimulated protein synthesis in pancreatic beta-cells parallels an increase in the availability of the translational ternary complex (eIF2-GTP.Met-tRNAi) and the dephosphorylation of eIF2 alpha. (Q40505852)

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English	Glucose-stimulated protein synthesis in pancreatic beta-cells parallels an increase in the availability of the translational ternary complex (eIF2-GTP.Met-tRNAi) and the dephosphorylation of eIF2 alpha.	scientific article

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3 January 2020

Glucose-stimulated protein synthesis in pancreatic beta-cells parallels an increase in the availability of the translational ternary complex (eIF2-GTP.Met-tRNAi) and the dephosphorylation of eIF2 alpha (English)

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3 January 2020

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Terence P. Herbert

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3 January 2020

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Edith Gomez

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3 January 2020

Michael L Powell

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3 January 2020

Isabel C Greenman

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8 October 2004

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3 January 2020

Journal of Biological Chemistry

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279

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3 January 2020

53937-53946

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3 January 2020

Glucose stimulation of the proinsulin synthesis in isolated pancreatic islets without increasing amount of proinsulin mRNA

1 reference

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21 January 2018

Regulation of the biosynthesis of insulin-secretory-granule proteins. Co-ordinate translational control is exerted on some, but not all, granule matrix constituents

1 reference

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21 January 2018

Glucose-regulated translational control of proinsulin biosynthesis with that of the proinsulin endopeptidases PC2 and PC3 in the insulin-producing MIN6 cell line

1 reference

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21 January 2018

Regulation by glucose of the biosynthesis of PC2, PC3 and proinsulin in (ob/ob) mouse islets of Langerhans

1 reference

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21 January 2018

Insulin mediates glucose-stimulated phosphorylation of PHAS-I by pancreatic beta cells. An insulin-receptor mechanism for autoregulation of protein synthesis by translation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408682200

21 January 2018

Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408682200

21 January 2018

PHAS-I as a link between mitogen-activated protein kinase and translation initiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408682200

21 January 2018

Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408682200

21 January 2018

Mechanisms of leucine- and theophylline-stimulated insulin biosynthesis in isolated rat pancreatic islets

1 reference

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21 January 2018

Biosynthesis of insulin secretory granule membrane proteins. Control by glucose.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408682200

21 January 2018

Glucose-induced translational control of proinsulin biosynthesis is proportional to preproinsulin mRNA levels in islet beta-cells but not regulated via a positive feedback of secreted insulin

1 reference

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21 January 2018

Glucose stimulates the activity of the guanine nucleotide-exchange factor eIF-2B in isolated rat islets of Langerhans

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408682200

21 January 2018

Eukaryotic initiation factor 2B (eIF2B).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408682200

21 January 2018

The guanine nucleotide-exchange factor, eIF-2B

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408682200

21 January 2018

PKR--a protein kinase regulated by double-stranded RNA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408682200

21 January 2018

PKR, apoptosis and cancer

1 reference

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21 January 2018

Glucose limitation induces GCN4 translation by activation of Gcn2 protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408682200

21 January 2018

Regulation of heme-regulated eIF-2 alpha kinase and its expression in erythroid cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408682200

21 January 2018

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408682200

21 January 2018

Regulated translation initiation controls stress-induced gene expression in mammalian cells

1 reference

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21 January 2018

Perk is essential for translational regulation and cell survival during the unfolded protein response

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408682200

21 January 2018

Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival

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21 January 2018

A simplified system for generating recombinant adenoviruses

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21 January 2018

cAMP-dependent protein kinase and Ca2+ influx through L-type voltage-gated calcium channels mediate Raf-independent activation of extracellular regulated kinase in response to glucagon-like peptide-1 in pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408682200

21 January 2018

Distinct signalling pathways mediate insulin and phorbol ester-stimulated eukaryotic initiation factor 4F assembly and protein synthesis in HEK 293 cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408682200

21 January 2018

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

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21 January 2018

The extracellular signal-regulated kinase pathway regulates the phosphorylation of 4E-BP1 at multiple sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408682200

21 January 2018

Pancreatic beta cell line MIN6 exhibits characteristics of glucose metabolism and glucose-stimulated insulin secretion similar to those of normal islets

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408682200

21 January 2018

Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408682200

21 January 2018

Glucose regulates EF-2 phosphorylation and protein translation by a protein phosphatase-2A-dependent mechanism in INS-1-derived 832/13 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408682200

21 January 2018

Translational control of insulin biosynthesis. Evidence for regulation of elongation, initiation and signal-recognition-particle-mediated translational arrest by glucose.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408682200

21 January 2018

Regulation of mammalian translation factors by nutrients

1 reference

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21 January 2018

mTOR integrates amino acid- and energy-sensing pathways

1 reference

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21 January 2018

Polypyrimidine tracts and their binding proteins: regulatory sites for posttranscriptional modulation of gene expression

1 reference

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21 January 2018

Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408682200

21 January 2018

Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408682200

21 January 2018

Multiple mechanisms control phosphorylation of PHAS-I in five (S/T)P sites that govern translational repression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408682200

21 January 2018

A quantitative molecular model for modulation of mammalian translation by the eIF4E-binding protein 1.

1 reference

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21 January 2018

Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha

1 reference

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21 January 2018

Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2

1 reference

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21 January 2018

Inhibition of a constitutive translation initiation factor 2alpha phosphatase, CReP, promotes survival of stressed cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408682200

21 January 2018

Translation mediated by the internal ribosome entry site of the cat-1 mRNA is regulated by glucose availability in a PERK kinase-dependent manner

1 reference

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21 January 2018

The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas

1 reference

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21 January 2018

Translational control is required for the unfolded protein response and in vivo glucose homeostasis

1 reference

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21 January 2018

The function of GADD34 is a recovery from a shutoff of protein synthesis induced by ER stress: elucidation by GADD34-deficient mice

1 reference

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21 January 2018

Translational control of proinsulin synthesis by glucose

1 reference

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21 January 2018

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10.1074/JBC.M408682200

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Europe PubMed Central

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3 January 2020

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Europe PubMed Central

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3 January 2020

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