Novel function of orphan nuclear receptor Nur77 in stabilizing hypoxia-inducible factor-1alpha (Q40512348)

21 September 2017

Novel function of orphan nuclear receptor Nur77 in stabilizing hypoxia-inducible factor-1alpha (English)

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21 September 2017

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Young-Gun Yoo

1

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21 September 2017

Myeong Goo Yeo

2

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21 September 2017

Dae Kyong Kim

3

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21 September 2017

Hyunsung Park

4

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21 September 2017

Mi-Ock Lee

5

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21 September 2017

language of work or name

English

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publication date

22 September 2004

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Journal of Biological Chemistry

21 September 2017

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21 September 2017

279

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21 September 2017

51

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21 September 2017

53365-53373

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Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology

21 September 2017

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https://api.crossref.org/works/10.1074%2FJBC.M408554200

Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

Differential regulation of HIF-1 alpha prolyl-4-hydroxylase genes by hypoxia in human cardiovascular cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M408554200

Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

Regulation and destabilization of HIF-1alpha by ARD1-mediated acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1alpha/ARNT

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1alpha in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

Hepatitis B virus X protein enhances transcriptional activity of hypoxia-inducible factor-1alpha through activation of mitogen-activated protein kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

Genes involved in T-cell receptor-mediated apoptosis of thymocytes and T-cell hybridomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

The orphan receptors NGFI-B and steroidogenic factor 1 establish monomer binding as a third paradigm of nuclear receptor-DNA interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

A novel pathway for vitamin A signaling mediated by RXR heterodimerization with NGFI-B and NURR1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

Novel dimeric Nur77 signaling mechanism in endocrine and lymphoid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

A gene inducible by serum growth factors encodes a member of the steroid and thyroid hormone receptor superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

Activation of the inducible orphan receptor gene nur77 by serum growth factors: dissociation of immediate-early and delayed-early responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

Involvement of JunD in transcriptional activation of the orphan receptor gene nur77 by nerve growth factor and membrane depolarization in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

Mitogenic Effect of Orphan Receptor TR3 and Its Regulation by MEKK1 in Lung Cancer Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate-early gene nur77.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

Requirement for the orphan steroid receptor Nur77 in apoptosis of T-cell hybridomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

Nuclear hormone receptors in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

Hepatitis B virus X protein induced expression of the Nur77 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

Regulation of the Nur77 orphan steroid receptor in activation-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

p38 Mitogen-activated protein kinase mediates hypoxic regulation of Mdm2 and p53 in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

Growth factor-mediated induction of HDM2 positively regulates hypoxia-inducible factor 1alpha expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

p53-Mdm2--the affair that never ends

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

Regulation of proliferation-survival decisions during tumor cell hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

Hypoxia links ATR and p53 through replication arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

LH induces orphan nuclear receptor Nur77 gene expression in testicular Leydig cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

Activation and induction of NUR77/NURR1 in corticotrophs by CRH/cAMP: involvement of calcium, protein kinase A, and MAPK pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

Nuclear receptor and apoptosis initiator NGFI-B is a substrate for kinase ERK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

Modulation of retinoic acid sensitivity in lung cancer cells through dynamic balance of orphan receptors nur77 and COUP-TF and their heterodimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

Ceramide-induced cell death is independent of the Fas/Fas ligand pathway and is prevented by Nur77 overexpression in A20 B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

Nur77 as a survival factor in tumor necrosis factor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

Nur77 activated by hypoxia-inducible factor-1alpha overproduces proopiomelanocortin in von Hippel-Lindau-mutated renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

Vascular endothelial growth factor-regulated gene expression in endothelial cells: KDR-mediated induction of Egr3 and the related nuclear receptors Nur77, Nurr1, and Nor1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408554200

21 January 2018

Identifiers

DOI

10.1074/JBC.M408554200

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21 September 2017

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