The liver X receptor ligand T0901317 down-regulates APOA5 gene expression through activation of SREBP-1c (Q40524290)

21 September 2017

The liver X receptor ligand T0901317 down-regulates APOA5 gene expression through activation of SREBP-1c (English)

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21 September 2017

Hélène Dehondt

4

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Len A. Pennacchio

series ordinal

6

object named as

Len A Pennacchio

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21 September 2017

2

Maxime Nowak

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21 September 2017

5

Dean W Hum

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21 September 2017

Jean-Charles Fruchart

series ordinal

8

object named as

Jean-Charles Fruchart

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21 September 2017

1

Heidelinde Jakel

1 reference

21 September 2017

Jamila Fruchart-Najib

series ordinal

7

object named as

Jamila Fruchart-Najib

1 reference

21 September 2017

Emanuelle Moitrot

3

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21 September 2017

language of work or name

English

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publication date

17 August 2004

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Journal of Biological Chemistry

21 September 2017

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21 September 2017

279

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21 September 2017

44

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21 September 2017

45462-45469

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Hypertriglyceridemia as a cardiovascular risk factor

21 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

Linkage and association between distinct variants of the APOA1/C3/A4/A5 gene cluster and familial combined hyperlipidemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

Two independent apolipoprotein A5 haplotypes influence human plasma triglyceride levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

Relative contribution of variation within the APOC3/A4/A5 gene cluster in determining plasma triglycerides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

The Human Apolipoprotein AV Gene Is Regulated by Peroxisome Proliferator-activated Receptor-α and Contains a Novel Farnesoid X-activated Receptor Response Element

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

Apolipoprotein A5, a crucial determinant of plasma triglyceride levels, is highly responsive to peroxisome proliferator-activated receptor alpha activators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

Role of LXRs in control of lipogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

Liver X receptors as insulin-mediating factors in fatty acid and cholesterol biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

Synthetic LXR ligand inhibits the development of atherosclerosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

T-0901317, a synthetic liver X receptor ligand, inhibits development of atherosclerosis in LDL receptor-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein particles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

Structure of the human gene encoding sterol regulatory element binding protein-1 (SREBF1) and localization of SREBF1 and SREBF2 to chromosomes 17p11.2 and 22q13

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

ADD1/SREBP-1c is required in the activation of hepatic lipogenic gene expression by glucose

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

Nutritional regulation of the fatty acid synthase promoter in vivo: sterol regulatory element binding protein functions through an upstream region containing a sterol regulatory element

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

Sterol regulation of acetyl coenzyme A carboxylase: a mechanism for coordinate control of cellular lipid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

Identification of glycerol-3-phosphate acyltransferase as an adipocyte determination and differentiation factor 1- and sterol regulatory element-binding protein-responsive gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

Sterol-regulated release of SREBP-2 from cell membranes requires two sequential cleavages, one within a transmembrane segment

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

Dual DNA binding specificity of ADD1/SREBP1 controlled by a single amino acid in the basic helix-loop-helix domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

Fibrates increase human apolipoprotein A-II expression through activation of the peroxisome proliferator-activated receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

Promoter analysis of the mouse sterol regulatory element-binding protein-1c gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

Peroxisome proliferator-activated receptor alpha (PPARalpha ) turnover by the ubiquitin-proteasome system controls the ligand-induced expression level of its target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

Mechanism of triglyceride lowering in mice expressing human apolipoprotein A5

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

Apolipoprotein A-V: a novel apolipoprotein associated with an early phase of liver regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

Adenoviral overexpression of apolipoprotein A-V reduces serum levels of triglycerides and cholesterol in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

Differential stimulation of cholesterol and unsaturated fatty acid biosynthesis in cells expressing individual nuclear sterol regulatory element-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

Sterol regulatory element-binding protein negatively regulates microsomal triglyceride transfer protein gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

Transcriptional regulation of human oxysterol 7alpha-hydroxylase by sterol response element binding protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

Differential effects of sterol regulatory binding proteins 1 and 2 on sterol 12 alpha-hydroxylase. SREBP-2 suppresses the sterol 12 alpha-hydroxylase promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

SREBP-1c and Sp1 interact to regulate transcription of the gene for phosphoenolpyruvate carboxykinase (GTP) in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

The E-box like sterol regulatory element mediates the suppression of human Delta-6 desaturase gene by highly unsaturated fatty acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

Induction of transcripts derived from promoter III of the acetyl-CoA carboxylase-alpha gene in mammary gland is associated with recruitment of SREBP-1 to a region of the proximal promoter defined by a DNase I hypersensitive site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

DNA binding specificity and transactivation properties of SREBP-2 bound to multiple sites on the human apoA-II promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

Angiopoietin-like protein 3 mediates hypertriglyceridemia induced by the liver X receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

Liver X Receptor Signaling Pathways in Cardiovascular Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404744200

21 January 2018

Identifiers

DOI

10.1074/JBC.M404744200

1 reference

21 September 2017

1 reference