Apc deficiency is associated with increased Egfr activity in the intestinal enterocytes and adenomas of C57BL/6J-Min/+ mice (Q40528401)

21 September 2017

Apc deficiency is associated with increased Egfr activity in the intestinal enterocytes and adenomas of C57BL/6J-Min/+ mice (English)

1 reference

21 September 2017

Amy E Moran

1

1 reference

21 September 2017

Daniel H Hunt

2

1 reference

21 September 2017

Sara H Javid

3

1 reference

21 September 2017

Mark Redston

4

1 reference

21 September 2017

Adelaide M Carothers

5

1 reference

21 September 2017

Monica M Bertagnolli

6

1 reference

21 September 2017

language of work or name

English

0 references

publication date

4 August 2004

1 reference

Journal of Biological Chemistry

21 September 2017

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21 September 2017

279

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21 September 2017

41

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21 September 2017

43261-43272

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The genetics of colorectal cancer

21 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Biology of the adenomatous polyposis coli tumor suppressor

21 January 2018

1 reference

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Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Intestinal adenomas can develop with a stable karyotype and stable microsatellites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Genotype-phenotype correlation in murine Apc mutation: differences in enterocyte migration and response to sulindac

21 January 2018

1 reference

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Plant phenolics decrease intestinal tumors in an animal model of familial adenomatous polyposis

21 January 2018

1 reference

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The EGF receptor family as targets for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Importance of epidermal growth factor receptor signaling in establishment of adenomas and maintenance of carcinomas during intestinal tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2)

21 January 2018

1 reference

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Non-steroidal anti-inflammatory drugs and molecular carcinogenesis of colorectal carcinomas

21 January 2018

1 reference

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The cyclooxygenase-2-selective inhibitors rofecoxib and celecoxib prevent colorectal neoplasia occurrence and recurrence

21 January 2018

1 reference

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Prostaglandin E2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy

21 January 2018

1 reference

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Prostaglandin E2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor

21 January 2018

1 reference

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Ligand-induced, receptor-mediated dimerization and activation of EGF receptor

21 January 2018

1 reference

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Signal transduction and endocytosis: close encounters of many kinds

21 January 2018

1 reference

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Role of protein ubiquitylation in regulating endocytosis of receptor tyrosine kinases

21 January 2018

1 reference

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Imaging sites of receptor dephosphorylation by PTP1B on the surface of the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

The Eps8 protein coordinates EGF receptor signalling through Rac and trafficking through Rab5

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

An effector region in Eps8 is responsible for the activation of the Rac-specific GEF activity of Sos-1 and for the proper localization of the Rac-based actin-polymerizing machine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Phosphoinositide 3-kinase activates Rac by entering in a complex with Eps8, Abi1, and Sos-1.

21 January 2018

1 reference

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A role for epidermal growth factor receptor, c-Src and focal adhesion kinase in an in vitro model for the progression of colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Protein-tyrosine phosphatase alpha regulates Src family kinases and alters cell-substratum adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

FAK integrates growth-factor and integrin signals to promote cell migration

21 January 2018

1 reference

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Epidermal growth factor-induced tumor cell invasion and metastasis initiated by dephosphorylation and downregulation of focal adhesion kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Beta-catenin mediates the interaction of the cadherin-catenin complex with epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

The epidermal growth factor receptor modulates the interaction of E-cadherin with the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

p120 Catenin-associated Fer and Fyn tyrosine kinases regulate beta-catenin Tyr-142 phosphorylation and beta-catenin-alpha-catenin Interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

EGFR signaling to p120-catenin through phosphorylation at Y228.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Integrins induce activation of EGF receptor: role in MAP kinase induction and adhesion-dependent cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Progressive changes in adherens junction structure during intestinal adenoma formation in Apc mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Src family protein-tyrosine kinases alter the function of PTEN to regulate phosphatidylinositol 3-kinase/AKT cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Rapid stimulation of pinocytosis in human carcinoma cells A-431 by epidermal growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Control of EGF receptor signaling by clathrin-mediated endocytosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Regulation of epidermal growth factor receptor signaling by endocytosis and intracellular trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

EGF receptor signaling stimulates SRC kinase phosphorylation of clathrin, influencing clathrin redistribution and EGF uptake.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Effect of tyrosine kinase inhibitors on clathrin-coated pit recruitment and internalization of epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Effect of clathrin heavy chain- and alpha-adaptin-specific small inhibitory RNAs on endocytic accessory proteins and receptor trafficking in HeLa cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Overexpression of cellular Src in fibroblasts enhances endocytic internalization of epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Endocytosis of Receptor Tyrosine Kinases Is Driven by Monoubiquitylation, Not Polyubiquitylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Recognition of the polyubiquitin proteolytic signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

AKT proto-oncogene overexpression is an early event during sporadic colon carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Involvement of the PI 3-kinase signaling pathway in progression of colon adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Mechanisms and consequences of activation of protein kinase B/Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Role of translocation in the activation and function of protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

21 January 2018

Phosphoinositide kinases

1 reference

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A Grb2-associated docking protein in EGF- and insulin-receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

An epidermal growth factor receptor/Gab1 signaling pathway is required for activation of phosphoinositide 3-kinase by lysophosphatidic acid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

A novel positive feedback loop mediated by the docking protein Gab1 and phosphatidylinositol 3-kinase in epidermal growth factor receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Src phosphorylates Grb2-associated binder 1 upon hepatocyte growth factor stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Activated type I phosphatidylinositol kinase is associated with the epidermal growth factor (EGF) receptor following EGF stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Interaction of phosphatidylinositol 3-kinase-associated p85 with epidermal growth factor and platelet-derived growth factor receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

EGF-Receptor phosphorylation and signaling are targeted by H2O2 redox stress

21 January 2018

1 reference

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Epidermal growth factor receptor activation under oxidative stress fails to promote c-Cbl mediated down-regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Src-catalyzed phosphorylation of c-Cbl leads to the interdependent ubiquitination of both proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Src promotes destruction of c-Cbl: implications for oncogenic synergy between Src and growth factor receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Role of Src expression and activation in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Potentiation of epidermal growth factor receptor-mediated oncogenesis by c-Src: implications for the etiology of multiple human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Cyclooxygenase regulates angiogenesis induced by colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells independently of Bcl-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Celecoxib induces apoptosis by inhibiting 3-phosphoinositide-dependent protein kinase-1 activity in the human colon cancer HT-29 cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Activation of mitogen-activated protein kinase by H2O2. Role in cell survival following oxidant injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Activation of cytosolic phospholipase A2 in Her14 fibroblasts by hydrogen peroxide: a p42/44(MAPK)-dependent and phosphorylation-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

The secretory phospholipase A2 gene is a candidate for the Mom1 locus, a major modifier of ApcMin-induced intestinal neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Recent advances in molecular biology and physiology of the prostaglandin E2-biosynthetic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Secretory phospholipase A(2) inhibits epidermal growth factor-induced receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Inhibition of endosome fusion by phospholipase A2 (PLA2) inhibitors points to a role for PLA2 in endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

EGFR signal transactivation in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Characterization and identification of an epidermal-growth-factor-activated phospholipase A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Epidermal growth factor (EGF) induces serine phosphorylation-dependent activation and calcium-dependent translocation of the cytosolic phospholipase A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Live and let die in the intestinal epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

Regulation of epithelial cell migration and tumor formation by beta-catenin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

E-cadherin-mediated adhesion inhibits ligand-dependent activation of diverse receptor tyrosine kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M404276200

A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells

21 January 2018

1 reference

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Intestinal barrier: An interface between health and disease

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M404276200

1 reference

release_evcod4q3pfgwje4u4dh37t54aq

21 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/evcod4q3pfgwje4u4dh37t54aq

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference