RNA helicase DDX3: a novel therapeutic target in Ewing sarcoma (Q40545030)

21 September 2017

RNA helicase DDX3: a novel therapeutic target in Ewing sarcoma (English)

1 reference

21 September 2017

1

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2 June 2020

author name string

C Kim

2

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2 June 2020

G McCarty

3

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2 June 2020

E A Montgomery

4

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2 June 2020

K Kammers

5

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2 June 2020

L R DeVine

6

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2 June 2020

R N Cole

7

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2 June 2020

V Raman

8

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2 June 2020

D M Loeb

9

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2 June 2020

language of work or name

English

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publication date

14 September 2015

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21 September 2017

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2 June 2020

volume

35

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2 June 2020

issue

20

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2 June 2020

page(s)

2574-2583

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https://scigraph.springernature.com/pub.10.1038/onc.2015.336

2 June 2020

exact match

0 references

cites work

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A temperature-sensitive mutant of the mammalian RNA helicase, DEAD-BOX X isoform, DBX, defective in the transition from G1 to S phase.

21 January 2018

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DDX3 regulates cell growth through translational control of cyclin E1

21 January 2018

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The DEAD-box RNA helicase DDX3 associates with export messenger ribonucleoproteins as well as tip-associated protein and participates in translational control

21 January 2018

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DEAD-box protein DDX3 associates with eIF4F to promote translation of selected mRNAs

21 January 2018

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Novel, Broad Spectrum Anti-Cancer Agents Containing the Tricyclic 5:7:5-Fused Diimidazodiazepine Ring System

21 January 2018

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Targeting DDX3 with a small molecule inhibitor for lung cancer therapy

21 January 2018

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A spatially and temporally restricted mouse model of soft tissue sarcoma.

21 January 2018

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Targeting the human DEAD-box polypeptide 3 (DDX3) RNA helicase as a novel strategy to inhibit viral replication

21 January 2018

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High ALDH activity identifies chemotherapy-resistant Ewing's sarcoma stem cells that retain sensitivity to EWS-FLI1 inhibition

21 January 2018

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High prevalence of CIC fusion with double-homeobox (DUX4) transcription factors in EWSR1-negative undifferentiated small blue round cell sarcomas.

21 January 2018

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Distinct transcriptional signature and immunoprofile of CIC-DUX4 fusion-positive round cell tumors compared to EWSR1-rearranged Ewing sarcomas: further evidence toward distinct pathologic entities

21 January 2018

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Expression of the RNA helicase DDX3 and the hypoxia response in breast cancer

21 January 2018

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The DEAD-box helicase DDX3 supports the assembly of functional 80S ribosomes

21 January 2018

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Human DDX3 functions in translation and interacts with the translation initiation factor eIF3

21 January 2018

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Candidate tumor suppressor DDX3 RNA helicase specifically represses cap-dependent translation by acting as an eIF4E inhibitory protein

21 January 2018

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Novel mutations target distinct subgroups of medulloblastoma.

21 January 2018

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DDX3, a DEAD box RNA helicase, is deregulated in hepatitis virus-associated hepatocellular carcinoma and is involved in cell growth control

21 January 2018

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DDX3 loss by p53 inactivation promotes tumor malignancy via the MDM2/Slug/E-cadherin pathway and poor patient outcome in non-small-cell lung cancer

21 January 2018

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The role of DDX3 in regulating Snail

21 January 2018

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Identification of an antiapoptotic protein complex at death receptors

21 January 2018

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DDX3 regulates DNA damage-induced apoptosis and p53 stabilization

21 January 2018

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Oncogenic role of DDX3 in breast cancer biogenesis.

21 January 2018

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Differential in vitro sensitivity of human tumor and normal cells to chemotherapeutic agents and resistance modulators

21 January 2018

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Oncoprotein EWS-FLI1 activity is enhanced by RNA helicase A.

21 January 2018

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A small molecule blocking oncogenic protein EWS-FLI1 interaction with RNA helicase A inhibits growth of Ewing's sarcoma

21 January 2018

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MLL-rearranged acute lymphoblastic leukaemia stem cell interactions with bone marrow stroma promote survival and therapeutic resistance that can be overcome with CXCR4 antagonism

21 January 2018

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Connexin-43 in the osteogenic BM niche regulates its cellular composition and the bidirectional traffic of hematopoietic stem cells and progenitors.

21 January 2018

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Statistical inference from multiple iTRAQ experiments without using common reference standards

21 January 2018

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Eight-channel iTRAQ enables comparison of the activity of six leukemogenic tyrosine kinases

21 January 2018

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21 January 2018

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Linear models and empirical bayes methods for assessing differential expression in microarray experiments

21 January 2018

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Nectin-2 and DDX3 are biomarkers for metastasis and poor prognosis of squamous cell/adenosquamous carcinomas and adenocarcinoma of gallbladder

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/26364611

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Characterization of cell lines derived from xenografts of childhood rhabdomyosarcoma

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PubMed

https://pubmed.ncbi.nlm.nih.gov/26364611

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Do human RNA helicases have a role in cancer?

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PubMed

https://pubmed.ncbi.nlm.nih.gov/26364611