Clozapine reverses hyperthermia and sympathetically mediated cutaneous vasoconstriction induced by 3,4-methylenedioxymethamphetamine (ecstasy) in rabbits and rats. (Q40554405)

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scientific article published on July 2003

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English	Clozapine reverses hyperthermia and sympathetically mediated cutaneous vasoconstriction induced by 3,4-methylenedioxymethamphetamine (ecstasy) in rabbits and rats.	scientific article published on July 2003

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scholarly article

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5 November 2019

Clozapine reverses hyperthermia and sympathetically mediated cutaneous vasoconstriction induced by 3,4-methylenedioxymethamphetamine (ecstasy) in rabbits and rats (English)

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5 November 2019

vasoconstriction

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Nigel P Pedersen

3

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5 November 2019

author name string

W W Blessing

1

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5 November 2019

B Seaman

2

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5 November 2019

Y Ootsuka

4

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5 November 2019

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1 July 2003

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5 November 2019

Journal of Neuroscience

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5 November 2019

23

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5 November 2019

15

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5 November 2019

6385-6391

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5 November 2019

Serotonin and Hallucinogens

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https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

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The role of serotonin in antipsychotic drug action

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https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

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Ten years of 'ecstasy'

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https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

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A review of central 5-HT receptors and their function

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https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

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Comparative effects of serotonergic agonists with varying efficacy at the 5-HT(1A) receptor on core body temperature: modification by the selective 5-HT(1A) receptor antagonist WAY 100635

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https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional blood flow and nociceptive stimuli in rabbits: patterning by medullary raphe, not ventrolateral medulla

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https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

based on heuristic

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Single-unit responses of serotonergic medullary and pontine raphe neurons to environmental cooling in freely moving cats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

based on heuristic

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Psychological and physiological effects of MDMA ("Ecstasy") after pretreatment with the 5-HT(2) antagonist ketanserin in healthy humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

based on heuristic

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Tail artery blood flow measured by chronically implanted Doppler ultrasonic probes in unrestrained conscious rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

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Raphe magnus/pallidus neurons regulate tail but not mesenteric arterial blood flow in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

based on heuristic

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5-hydroxytryptamine2A receptor inverse agonists as antipsychotics

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

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Cutaneous vasoconstriction contributes to hyperthermia induced by 3,4-methylenedioxymethamphetamine (ecstasy) in conscious rabbits.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comprehensive review of MDMA and GHB: two common club drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pharmacology of the acute hyperthermic response that follows administration of 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') to rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the medullary raphé in thermoregulatory vasomotor control in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thermoregulatory control of sympathetic fibres supplying the rat's tail

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rhythmic activities of the sympatho-excitatory neurons in the medulla of rabbits: neurons controlling cutaneous vasomotion

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5-hydroxytryptamine(2A) receptors regulate sympathetic nerves constricting the cutaneous vascular bed in rabbits and rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute Psychological and Neurophysiological Effects of MDMA in Humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

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Pyretogenic effect of lysergic acid diethylamide

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

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PHARMACOLOGICAL CHARACTERIZATION AND DETECTION OF HALLUCINOGENIC SUBSTANCES. I. HYPERTHERMIC ACTION IN THE RABBIT

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

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THE TAIL OF THE RAT, IN TEMPERATURE REGULATION AND ACCLIMATIZATION

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

based on heuristic

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Clozapine. A novel antipsychotic agent

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

based on heuristic

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Methylenedioxymethamphetamine induces spontaneous tail-flicks in the rat via 5-HT1A receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

based on heuristic

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Effects of 3,4-methylenedioxymethamphetamine on autonomic thermoregulatory responses of the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ecstasy: towards an understanding of the biochemical basis of the actions of MDMA

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

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Methylenedioxymethamphetamine-induced hyperthermia and neurotoxicity are independently mediated by 5-HT2 receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

based on heuristic

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Pharmacodynamic effects of serotonin (5-HT) receptor ligands in pigs: stimulation of 5-HT2 receptors induces malignant hyperthermia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

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Studies on the circulation in normotensive febrile patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

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Elevation of serum prolactin and corticosterone concentrations in the rat after the administration of 3,4-methylenedioxymethamphetamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

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Antagonism of serotonin receptor mediated neuroendocrine and temperature responses by atypical neuroleptics in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thermoregulatory responses to serotonin (5-HT) receptor stimulation in the rat. Evidence for opposing roles of 5-HT2 and 5-HT1A receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The response of individual sympathetic preganglionic neurones to microelectrophoretically applied endogenous monoamines

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A possible role of the serotonergic system in thermoregulation in the rabbit

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Review of the pharmacology and clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA or "Ecstasy").

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI)-induced hyperthermia in rats is mediated by stimulation of 5-HT2A receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperthermia in psychostimulant overdose

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

based on heuristic

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Hyperthermia following MDMA administration in rats: effects of ambient temperature, water consumption, and chronic dosing

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preclinical characterization of the potential of the putative atypical antipsychotic MDL 100,907 as a potent 5-HT2A antagonist with a favorable CNS safety profile

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ecstasy and neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Further evidence for clozapine as a dopamine D1 receptor agonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New dimensions in toxicology: hyperthermic syndrome following amphetamine derivatives

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutaneous vasoconstriction in conscious rabbits during alerting responses detected by hippocampal theta-rhythm

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperthermia and heat illness. Pathophysiological implications for avoidance and treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Do novel antipsychotics have similar pharmacological characteristics? A review of the evidence

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute effects of 3,4-methylenedioxymethamphetamine (MDMA) on 5-HT cell firing and release: comparison between dorsal and median raphe 5-HT systems

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CNS cell groups projecting to sympathetic outflow of tail artery: neural circuits involved in heat loss in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12867524

12 December 2020

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Identifiers

10.1523/JNEUROSCI.23-15-06385.2003

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12867524%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

PMC publication ID

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Europe PubMed Central

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5 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12867524%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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