An activin mutant with disrupted ALK4 binding blocks signaling via type II receptors (Q40559814)

21 September 2017

An activin mutant with disrupted ALK4 binding blocks signaling via type II receptors (English)

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21 September 2017

6

Wylie Vale

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author name string

Craig A Harrison

1

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21 September 2017

Peter C Gray

2

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21 September 2017

Wolfgang H Fischer

3

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21 September 2017

Cindy Donaldson

4

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21 September 2017

Senyon Choe

5

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21 September 2017

language of work or name

English

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publication date

27 April 2004

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Journal of Biological Chemistry

21 September 2017

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21 September 2017

279

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21 September 2017

27

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21 September 2017

28036-28044

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Mechanisms of TGF-beta signaling from cell membrane to the nucleus

21 September 2017

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https://api.crossref.org/works/10.1074%2FJBC.M402782200

TGF-beta signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402782200

Bone morphogenetic proteins: multifunctional regulators of vertebrate development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402782200

Nodal signalling in vertebrate development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402782200

TGFbeta signaling in growth control, cancer, and heritable disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402782200

A structural superfamily of growth factors containing a cystine knot motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402782200

Evolution and classification of cystine knot-containing hormones and related extracellular signaling molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402782200

How cells read TGF-beta signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402782200

Activation of signalling by the activin receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402782200

Activin and inhibin have antagonistic effects on ligand-dependent heteromerization of the type I and type II activin receptors and human erythroid differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402782200

The crystal structure of TGF-beta 3 and comparison to TGF-beta 2: implications for receptor binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402782200

Structures of an ActRIIB:activin A complex reveal a novel binding mode for TGF-beta ligand:receptor interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402782200

The BMP7/ActRII extracellular domain complex provides new insights into the cooperative nature of receptor assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402782200

Crystal structure of the BMP-2-BRIA ectodomain complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402782200

Identification of a functional binding site for activin on the type I receptor ALK4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402782200

Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402782200

Dual roles of Cripto as a ligand and coreceptor in the nodal signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402782200

Identification of two amino acids in activin A that are important for biological activity and binding to the activin type II receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402782200

Identification of a binding site on the type II activin receptor for activin and inhibin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402782200

Cell-specific transcriptional regulation of follicle-stimulating hormone-beta by activin and gonadotropin-releasing hormone in the LbetaT2 pituitary gonadotrope cell model

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402782200

BMP-2 antagonists emerge from alterations in the low-affinity binding epitope for receptor BMPR-II

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402782200

Localization of Activin A-, B-, and C-Subunits in Human Prostate and Evidence for Formation of New Activin Heterodimers of C-Subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402782200

Overexpression of activin beta(C) or activin beta(E) in the mouse liver inhibits regenerative deoxyribonucleic acid synthesis of hepatic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402782200

Identification of human activin and TGF beta type I receptors that form heteromeric kinase complexes with type II receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402782200

Cloning and characterization of a transmembrane serine kinase that acts as an activin type I receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402782200

Oligomeric structure of type I and type II transforming growth factor beta receptors: homodimers form in the ER and persist at the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402782200

Functional improvement of dystrophic muscle by myostatin blockade.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402782200

Activin signaling through activin receptor type II causes the cachexia-like symptoms in inhibin-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402782200

Induction of cachexia in mice by systemically administered myostatin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402782200

Impaired wound healing in transgenic mice overexpressing the activin antagonist follistatin in the epidermis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402782200

The roles of activin in cytoprotection and tissue repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402782200

Adenovirus-mediated overexpression of follistatin enlarges intact liver of adult rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402782200

Crystal structure of human bone morphogenetic protein-2 at 2.7 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M402782200

21 January 2018

Identifiers

DOI

10.1074/JBC.M402782200

1 reference

21 September 2017

1 reference