microRNA-122 target sites in the hepatitis C virus RNA NS5B coding region and 3' untranslated region: function in replication and influence of RNA secondary structure. (Q40563722)

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scientific article published on 27 September 2016

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English	microRNA-122 target sites in the hepatitis C virus RNA NS5B coding region and 3' untranslated region: function in replication and influence of RNA secondary structure.	scientific article published on 27 September 2016

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scholarly article

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24 March 2020

microRNA-122 target sites in the hepatitis C virus RNA NS5B coding region and 3' untranslated region: function in replication and influence of RNA secondary structure (English)

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24 March 2020

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Hepatitis C virus

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Ivo L. Hofacker

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Michael Niepmann

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Manja Marz

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Lyudmila Shalamova

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Lyudmila A Shalamova

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Gesche K Gerresheim

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Nadia Dünnes

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Anika Nieder-Röhrmann

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Markus Fricke

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24 March 2020

Christian Höner Zu Siederdissen

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publication date

27 September 2016

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Cellular and Molecular Life Sciences

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747-760

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24 March 2020

https://scigraph.springernature.com/pub.10.1007/s00018-016-2377-9

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Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

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Conserved microRNA targeting in Drosophila is as widespread in coding regions as in 3'UTRs

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Mapping the human miRNA interactome by CLASH reveals frequent noncanonical binding

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MicroRNA-10a binds the 5'UTR of ribosomal protein mRNAs and enhances their translation

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Gene silencing by microRNAs: contributions of translational repression and mRNA decay

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The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC.

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mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues

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MicroRNA binding sites in the coding region of mRNAs: extending the repertoire of post-transcriptional gene regulation

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21 January 2018

Increased siRNA duplex stability correlates with reduced off-target and elevated on-target effects

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Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex

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A three-dimensional view of the molecular machinery of RNA interference

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Structural basis for microRNA targeting

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21 January 2018

Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA

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21 January 2018

miR-122, a mammalian liver-specific microRNA, is processed from hcr mRNA and may downregulate the high affinity cationic amino acid transporter CAT-1.

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21 January 2018

Liver-specific microRNA-122: Biogenesis and function

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21 January 2018

The Hepatitis C Virus RNA 3'-Untranslated Region Strongly Enhances Translation Directed by the Internal Ribosome Entry Site

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21 January 2018

MicroRNA-122 dependent binding of Ago2 protein to hepatitis C virus RNA is associated with enhanced RNA stability and translation stimulation

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21 January 2018

Stabilization of hepatitis C virus RNA by an Ago2-miR-122 complex.

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21 January 2018

Base pairing between hepatitis C virus RNA and microRNA 122 3' of its seed sequence is essential for genome stabilization and production of infectious virus.

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https://api.crossref.org/works/10.1007%2FS00018-016-2377-9

21 January 2018

Competing and noncompeting activities of miR-122 and the 5' exonuclease Xrn1 in regulation of hepatitis C virus replication.

1 reference

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21 January 2018

microRNA-122 stimulates translation of hepatitis C virus RNA

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21 January 2018

Activation of hepatitis C virus translation by a liver-specific microRNA.

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https://api.crossref.org/works/10.1007%2FS00018-016-2377-9

21 January 2018

Regulation of hepatitis C virus translation and infectious virus production by the microRNA miR-122

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https://api.crossref.org/works/10.1007%2FS00018-016-2377-9

21 January 2018

miR-122 activates hepatitis C virus translation by a specialized mechanism requiring particular RNA components

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https://api.crossref.org/works/10.1007%2FS00018-016-2377-9

21 January 2018

Human Ago2 is required for efficient microRNA 122 regulation of hepatitis C virus RNA accumulation and translation.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-016-2377-9

21 January 2018

Stimulation of Hepatitis C Virus RNA translation by microRNA-122 occurs under different conditions in vivo and in vitro

1 reference

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21 January 2018

Differential stimulation of hepatitis C virus RNA translation by microRNA-122 in different cell cycle phases

1 reference

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21 January 2018

Conserved RNA secondary structures and long-range interactions in hepatitis C viruses

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https://api.crossref.org/works/10.1007%2FS00018-016-2377-9

21 January 2018

The role of site accessibility in microRNA target recognition

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21 January 2018

How microRNAs choose their targets

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Efficient use of accessibility in microRNA target prediction

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21 January 2018

CLIP-based prediction of mammalian microRNA binding sites

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https://api.crossref.org/works/10.1007%2FS00018-016-2377-9

21 January 2018

Hepatitis C virus RNA functionally sequesters miR-122

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https://api.crossref.org/works/10.1007%2FS00018-016-2377-9

21 January 2018

Competing roles of microRNA-122 recognition elements in hepatitis C virus RNA.

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21 January 2018

Micro-RNA regulation of the mammalian lin-28 gene during neuronal differentiation of embryonal carcinoma cells

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21 January 2018

Determinants of targeting by endogenous and exogenous microRNAs and siRNAs

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21 January 2018

Unconventional miR-122 binding stabilizes the HCV genome by forming a trimolecular RNA structure

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21 January 2018

Potent effect of target structure on microRNA function.

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21 January 2018

Analysis of the accessibility of CLIP bound sites reveals that nucleation of the miRNA:mRNA pairing occurs preferentially at the 3'-end of the seed match

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21 January 2018

A biophysical miRNA-mRNA interaction model infers canonical and noncanonical targets

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Hepatitis C virus RNA replication is resistant to tumour necrosis factor-alpha

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21 January 2018

Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line

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Complete replication of hepatitis C virus in cell culture

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Efficient replication of the genotype 2a hepatitis C virus subgenomic replicon

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Construction and characterization of infectious intragenotypic and intergenotypic hepatitis C virus chimeras

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Identification of human microRNA targets from isolated argonaute protein complexes

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A multifunctional human Argonaute2-specific monoclonal antibody

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ViennaRNA Package 2.0

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Incorporating chemical modification constraints into a dynamic programming algorithm for prediction of RNA secondary structure

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VARNA: Interactive drawing and editing of the RNA secondary structure

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Target site effects in the RNA interference and microRNA pathways

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Hepatitis C virus proteins: from structure to function

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https://pubmed.ncbi.nlm.nih.gov/27677491

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatitis C virus RNA replication

1 reference

https://pubmed.ncbi.nlm.nih.gov/27677491

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The 3'-untranslated region of hepatitis C virus RNA enhances translation from an internal ribosomal entry site

1 reference

https://pubmed.ncbi.nlm.nih.gov/27677491

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatitis C virus RNA translation

1 reference

https://pubmed.ncbi.nlm.nih.gov/27677491

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functionally conserved architecture of hepatitis C virus RNA genomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/27677491

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00018-016-2377-9

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27677491%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27677491%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

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