Induction of somatic hypermutation is associated with modifications in immunoglobulin variable region chromatin (Q40625542)

22 September 2017

Induction of somatic hypermutation is associated with modifications in immunoglobulin variable region chromatin (English)

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22 September 2017

3

Matthew D Scharff

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22 September 2017

Caroline J Woo

1

1 reference

PubMed ID

14563313

22 September 2017

Alberto Martin

series ordinal

2

1 reference

PubMed ID

14563313

22 September 2017

language of work or name

English

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publication date

1 October 2003

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22 September 2017

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22 September 2017

19

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22 September 2017

4

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22 September 2017

479-489

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Ordered recruitment of chromatin modifying and general transcription factors to the IFN-beta promoter

22 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Deciphering the transcriptional histone acetylation code for a human gene

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Increased transcription levels induce higher mutation rates in a hypermutating cell line

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https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Histone modifications in transcriptional regulation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/matrix attachment region

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

DNA Double-Strand Breaks in Immunoglobulin Genes Undergoing Somatic Hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

ChIPs of the beta-globin locus: unraveling gene regulation within an active domain

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Genomic instability in mice lacking histone H2AX

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https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Transcription-targeted DNA deamination by the AID antibody diversification enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Stepwise activation of the immunoglobulin mu heavy chain gene locus

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Induction of somatic mutation in a human B cell line in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Induction of somatic hypermutation in immunoglobulin genes is dependent on DNA polymerase iota.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

AID-dependent somatic hypermutation occurs as a DNA single-strand event in the BL2 cell line

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Somatic hypermutation in the heavy chain locus correlates with transcription.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Activation of p53 in MDM2-overexpressing cells through phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Translating the Histone Code

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Changes in histone acetylation are associated with differences in accessibility of V(H) gene segments to V-DJ recombination during B-cell ontogeny and development

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Promotion of antigen-specific antibody production in murine B cells by a moderate increase in histone acetylation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Histone acetylation and hSWI/SNF remodeling act in concert to stimulate V(D)J cleavage of nucleosomal DNA

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Boundaries of somatic mutation in rearranged immunoglobulin genes: 5' boundary is near the promoter, and 3' boundary is approximately 1 kb from V(D)J gene

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Dynamic analysis of proviral induction and De Novo methylation: implications for a histone deacetylase-independent, methylation density-dependent mechanism of transcriptional repression

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Chromatin remodeling at the Ig loci prior to V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Somatic hypermutation: how many mechanisms diversify V region sequences?

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Somatic hypermutation of the AID transgene in B and non-B cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Activation-induced cytidine deaminase turns on somatic hypermutation in hybridomas

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

A role for histone acetylation in the developmental regulation of VDJ recombination.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Effects of Sequence and Structure on the Hypermutability of Immunoglobulin Genes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Cell-cycle-regulated DNA double-stranded breaks in somatic hypermutation of immunoglobulin genes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Somatic hypermutation of immunoglobulin genes is linked to transcription initiation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Expression of error-prone polymerases in BL2 cells activated for Ig somatic hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

The 5' hypermutation boundary of kappa chains is independent of local and neighbouring sequences and related to the distance from the initiation of transcription.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

TdT-accessible breaks are scattered over the immunoglobulin V domain in a constitutively hypermutating B cell line

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

In vivo and in vitro studies of immunoglobulin gene somatic hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Photobleaching of GFP-labeled H2AX in chromatin: H2AX has low diffusional mobility in the nucleus.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Accessibility control of antigen-receptor variable-region gene assembly: role of cis-acting elements

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Molecular aspects of somatic hypermutation of immunoglobulin genes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Somatic hypermutation of immunoglobulin and non-immunoglobulin genes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

The transcriptional promoter regulates hypermutation of the antibody heavy chain locus

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

Variability in the Lambda Light Chain Sequences of Mouse Antibody

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2803%2900261-9

7 January 2021

10.1016/S1074-7613(03)00261-9

Identifiers

DOI

1 reference

22 September 2017

1 reference

PubMed ID

14563313