Novel target for induction of apoptosis by cyclo-oxygenase-2 inhibitor SC-236 through a protein kinase C-beta(1)-dependent pathway (Q40636925)

22 September 2017

Novel target for induction of apoptosis by cyclo-oxygenase-2 inhibitor SC-236 through a protein kinase C-beta(1)-dependent pathway (English)

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22 September 2017

Xiao-Hua Jiang

1

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22 September 2017

Shiu-Kum Lam

2

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22 September 2017

Marie C M Lin

3

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22 September 2017

Shi-Hu Jiang

4

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22 September 2017

Hsiang-Fu Kung

5

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22 September 2017

Eric D Slosberg

6

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22 September 2017

Jae Won Soh

7

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22 September 2017

I Bernard Weinstein

8

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22 September 2017

Benjamin Chun-Yu Wong

9

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22 September 2017

language of work or name

English

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publication date

1 September 2002

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22 September 2017

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22 September 2017

21

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22 September 2017

39

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22 September 2017

6113-6122

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1205778

22 September 2017

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Intracellular unesterified arachidonic acid signals apoptosis

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Expression of protein kinase C beta1 confers resistance to TNFalpha- and paclitaxel-induced apoptosis in HT-29 colon carcinoma cells

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Cyclooxygenase, NSAIDs, and colorectal cancer

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Protein kinase C isozyme-mediated cell cycle arrest involves induction of p21(waf1/cip1) and p27(kip1) and hypophosphorylation of the retinoblastoma protein in intestinal epithelial cells

21 January 2018

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Aspirin, NSAIDS, and colon cancer prevention: mechanisms?

21 January 2018

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Effects of nonsteroidal anti-inflammatory drugs on proliferation and on induction of apoptosis in colon cancer cells by a prostaglandin-independent pathway.

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PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs

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The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells independently of Bcl-2

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Protein kinase C isoenzymes: divergence in signal transduction?

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Protein kinase C isozymes and substrates

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Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: insight into mechanisms and implications for cancer growth and ulcer healing

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Growth stimulation and induction of epidermal growth factor receptor by overexpression of cyclooxygenases 1 and 2 in human colon carcinoma cells

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Protein kinase C alpha activates RAF-1 by direct phosphorylation

21 January 2018

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Prostaglandin E prevents indomethacin-induced gastric and intestinal damage through different EP receptor subtypes

21 January 2018

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Cyclo-oxygenase-2: pharmacology, physiology, biochemistry and relevance to NSAID therapy

21 January 2018

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The molecular heterogeneity of protein kinase C and its implications for cellular regulation

21 January 2018

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Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C

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Growth inhibition and induction of apoptosis in colorectal tumor cells by cyclooxygenase inhibitors

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Potentiation of apoptosis by treatment with the protein kinase C-specific inhibitor safingol in mitomycin C-treated gastric cancer cells

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Protein kinase C: a novel target for inhibiting gastric cancer cell invasion

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Sulindac sulfide, an aspirin-like compound, inhibits proliferation, causes cell cycle quiescence, and induces apoptosis in HT-29 colon adenocarcinoma cells

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15-LOX-1: a novel molecular target of nonsteroidal anti-inflammatory drug-induced apoptosis in colorectal cancer cells

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Identification of a phorbol ester-repressible v-src-inducible gene

21 January 2018

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The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis

21 January 2018

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Upregulation of p21(WAF1/CIP1) leads to morphologic changes and esterase activity in TPA-mediated differentiation of human prostate cancer cell line TSU-Pr1.

21 January 2018

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Antiangiogenic and antitumor effects of a protein kinase Cbeta inhibitor in murine lewis lung carcinoma and human Calu-6 non-small-cell lung carcinoma xenografts

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Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential

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Suppression of NF-kappaB activity by sulfasalazine is mediated by direct inhibition of IkappaB kinases alpha and beta

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Malignant transformation and antineoplastic actions of nonsteroidal antiinflammatory drugs (NSAIDs) on cyclooxygenase-null embryo fibroblasts

21 January 2018

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Non-steroidal anti-inflammatory drug-induced apoptosis in gastric cancer cells is blocked by protein kinase C activation through inhibition of c-myc

21 January 2018

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Overexpression of protein kinase C-beta1 isoenzyme suppresses indomethacin-induced apoptosis in gastric epithelial cells

21 January 2018

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MAPK-dependent expression of p21(WAF) and p27(kip1) in PMA-induced differentiation of HL60 cells

21 January 2018

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7 January 2021

Isoenzymes of protein kinase C: differential involvement in apoptosis and pathogenesis

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Inhibition of NF-kappaB and AP-1 activation by R- and S-flurbiprofen

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Transcriptional regulation of human prostaglandin-endoperoxide synthase-2 gene by lipopolysaccharide and phorbol ester in vascular endothelial cells. Involvement of both nuclear factor for interleukin-6 expression site and cAMP response element

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Cyclooxygenase-2 inhibitors suppress the growth of gastric cancer xenografts via induction of apoptosis in nude mice

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7 January 2021

Overexpression of the wild-type p53 gene inhibits NF-kappaB activity and synergizes with aspirin to induce apoptosis in human colon cancer cells

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7 January 2021

Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2

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7 January 2021

Elevated cyclooxygenase-2 levels in Min mouse adenomas

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205778

1 reference

Dimensions Publication ID

22 September 2017

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1 reference