Hsp105alpha suppresses the aggregation of truncated androgen receptor with expanded CAG repeats and cell toxicity (Q40652242)

22 September 2017

Hsp105alpha suppresses the aggregation of truncated androgen receptor with expanded CAG repeats and cell toxicity (English)

1 reference

22 September 2017

4

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22 September 2017

6

Gen Sobue

1 reference

22 September 2017

Keiichi Ishihara

1

1 reference

22 September 2017

Nobuyuki Yamagishi

2

1 reference

22 September 2017

Youhei Saito

3

1 reference

22 September 2017

Yasushi Kobayashi

5

1 reference

22 September 2017

Kenzo Ohtsuka

7

1 reference

22 September 2017

Takumi Hatayama

8

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22 September 2017

language of work or name

English

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publication date

24 April 2003

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Journal of Biological Chemistry

22 September 2017

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22 September 2017

278

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22 September 2017

27

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22 September 2017

25143-25150

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Progressive proximal spinal and bulbar muscular atrophy of late onset. A sex-linked recessive trait

22 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Nuclear inclusions of the androgen receptor protein in spinal and bulbar muscular atrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Nonneural nuclear inclusions of androgen receptor protein in spinal and bulbar muscular atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Unstable expansion of CAG repeat in hereditary dentatorubral-pallidoluysian atrophy (DRPLA)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Dentatorubral and pallidoluysian atrophy expansion of an unstable CAG trinucleotide on chromosome 12p

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

CAG expansions in a novel gene for Machado-Joseph disease at chromosome 14q32.1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Expansion of an unstable trinucleotide CAG repeat in spinocerebellar ataxia type 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Moderate expansion of a normally biallelic trinucleotide repeat in spinocerebellar ataxia type 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Identification of the spinocerebellar ataxia type 2 gene using a direct identification of repeat expansion and cloning technique, DIRECT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Cloning of the gene for spinocerebellar ataxia 2 reveals a locus with high sensitivity to expanded CAG/glutamine repeats

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Autosomal dominant cerebellar ataxia (SCA6) associated with small polyglutamine expansions in the alpha 1A-voltage-dependent calcium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Cloning of the SCA7 gene reveals a highly unstable CAG repeat expansion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Chaperoning brain diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Aggresomes: a cellular response to misfolded proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Molecular pathogenesis of movement disorders: are protein aggregates a common link in neuronal degeneration?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Inhibition of huntingtin fibrillogenesis by specific antibodies and small molecules: implications for Huntington's disease therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Genetic suppression of polyglutamine toxicity in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Molecular chaperone functions of heat-shock proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Molecular chaperones in cellular protein folding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Polyglutamine length-dependent interaction of Hsp40 and Hsp70 family chaperones with truncated N-terminal huntingtin: their role in suppression of aggregation and cellular toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Effects of heat shock, heat shock protein 40 (HDJ-2), and proteasome inhibition on protein aggregation in cellular models of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Molecular cloning, expression and localization of human 105 kDa heat shock protein, hsp105

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Cloning and expression of murine high molecular mass heat shock proteins, HSP105.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Identification of a major subfamily of large hsp70-like proteins through the cloning of the mammalian 110-kDa heat shock protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Characterization of an 88-kDa heat shock protein of Neurospora crassa that interacts with Hsp30.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Identification of an Arabidopsis thaliana cDNA encoding a HSP70-related protein belonging to the HSP110/SSE1 subfamily.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Isolation and characterization of SSE1 and SSE2, new members of the yeast HSP70 multigene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Characteristic expression of 105-kDa heat shock protein (HSP105) in various tissues of nonstressed and heat-stressed rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Role of hsp105 in protection against stress-induced apoptosis in neuronal PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Cleavage, aggregation and toxicity of the expanded androgen receptor in spinal and bulbar muscular atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Common antigenicity of mouse 42 degrees C-specific heat-shock protein with mouse HSP 105.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Testosterone reduction prevents phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Interaction of Hsp70 chaperones with substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

The Hsp70 and Hsp60 chaperone machines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

CREB-binding protein sequestration by expanded polyglutamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Insoluble detergent-resistant aggregates form between pathological and nonpathological lengths of polyglutamine in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Aberrant interactions of transcriptional repressor proteins with the Huntington's disease gene product, huntingtin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Expanded polyglutamine stretches interact with TAFII130, interfering with CREB-dependent transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Chaperone suppression of cellular toxicity of huntingtin is independent of polyglutamine aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Inhibition of polyglutamine protein aggregation and cell death by novel peptides identified by phage display screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Triggering of neuronal cell death by accumulation of activated SEK1 on nuclear polyglutamine aggregations in PML bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

X-linked recessive bulbospinal neuronopathy. A clinicopathological study

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Chaperones Hsp70 and Hsp40 suppress aggregate formation and apoptosis in cultured neuronal cells expressing truncated androgen receptor protein with expanded polyglutamine tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Modulation of the chaperone activities of Hsc70/Hsp40 by Hsp105alpha and Hsp105beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

Hsp70 and Hsp40 chaperone activities in the cytoplasm and the nucleus of mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302975200

21 January 2018

Identifiers

DOI

10.1074/JBC.M302975200

1 reference

22 September 2017

1 reference