Inhibition of amino acid-mTOR signaling by a leucine derivative induces G1 arrest in Jurkat cells (Q40673162)

22 September 2017

Inhibition of amino acid-mTOR signaling by a leucine derivative induces G1 arrest in Jurkat cells (English)

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22 September 2017

4

Kenta Hara

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22 September 2017

Sujuti Hidayat

1

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22 September 2017

Ken-ichi Yoshino

2

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22 September 2017

Chiharu Tokunaga

3

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22 September 2017

Masafumi Matsuo

5

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22 September 2017

Kazuyoshi Yonezawa

6

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22 September 2017

1 February 2003

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Biochemical and Biophysical Research Communications

22 September 2017

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22 September 2017

301

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22 September 2017

2

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22 September 2017

417-423

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Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast

22 September 2017

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https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

TOR controls translation initiation and early G1 progression in yeast

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

The TOR signaling cascade regulates gene expression in response to nutrients

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

Rapamycin-modulated transcription defines the subset of nutrient-sensitive signaling pathways directly controlled by the Tor proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

FKBP12-rapamycin target TOR2 is a vacuolar protein with an associated phosphatidylinositol-4 kinase activity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

Control of p70 s6 kinase by kinase activity of FRAP in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

Immunopurified mammalian target of rapamycin phosphorylates and activates p70 S6 kinase alpha in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

PHAS-I as a link between mitogen-activated protein kinase and translation initiation

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

Insulin signal transduction through protein kinase cascades.

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

Repression of cap-dependent translation by 4E-binding protein 1: competition with p220 for binding to eukaryotic initiation factor-4E

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

Amino acid-dependent control of p70(s6k). Involvement of tRNA aminoacylation in the regulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

Amino acid availability regulates p70 S6 kinase and multiple translation factors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

Bidirectional modulation of insulin action by amino acids

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

Regulation of translational effectors by amino acid and mammalian target of rapamycin signaling pathways. Possible involvement of autophagy in cultured hepatoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

Branched-chain amino acids are essential in the regulation of PHAS-I and p70 S6 kinase by pancreatic beta-cells. A possible role in protein translation and mitogenic signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

Amino acids stimulate phosphorylation of p70S6k and organization of rat adipocytes into multicellular clusters

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

Structural requirement of leucine for activation of p70 S6 kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

Regulation of amino acid-sensitive TOR signaling by leucine analogues in adipocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

Rapamycin blocks cell cycle progression of activated T cells prior to events characteristic of the middle to late G1 phase of the cycle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

Mechanism of action of the immunosuppressant rapamycin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

The retinoblastoma gene product is a cell cycle-dependent, nuclear matrix-associated protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

Tumor-suppressor p53 and the cell cycle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

Leucine-specific binding of photoreactive Leu7-MAP to a high molecular weight protein on the plasma membrane of the isolated rat hepatocyte

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

The permease homologue Ssy1p controls the expression of amino acid and peptide transporter genes in Saccharomyces cerevisiae.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

Ssy1p and Ptr3p are plasma membrane components of a yeast system that senses extracellular amino acids

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

Expression cloning and characterization of a transporter for large neutral amino acids activated by the heavy chain of 4F2 antigen (CD98)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

Intracellular sensing of amino acids in Xenopus laevis oocytes stimulates p70 S6 kinase in a target of rapamycin-dependent manner

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

FRAP/mTOR is required for proliferation and patterning during embryonic development in the mouse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2903052-8

10.1016/S0006-291X(02)03052-8

7 January 2021

Identifiers

DOI

1 reference

22 September 2017

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