Quality and quantity of TFH cells are critical for broad antibody development in SHIVAD8 infection (Q40681333)

22 September 2017

Quality and quantity of TFH cells are critical for broad antibody development in SHIVAD8 infection (English)

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22 September 2017

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T follicular helper cell

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1

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22 September 2017

17

John R Mascola

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22 September 2017

13

Brandon F Keele

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22 September 2017

19

Richard A Koup

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22 September 2017

11

Adrian B McDermott

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22 September 2017

Rebecca M Lynch

2

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22 September 2017

Rajeev Gautam

3

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22 September 2017

Rodrigo Matus-Nicodemos

4

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22 September 2017

Stephen D Schmidt

5

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22 September 2017

Kristin L Boswell

6

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22 September 2017

Sam Darko

7

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22 September 2017

Patrick Wong

8

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22 September 2017

Zizhang Sheng

9

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22 September 2017

Constantinos Petrovas

10

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22 September 2017

Robert A Seder

12

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22 September 2017

Lawrence Shapiro

14

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22 September 2017

Daniel C Douek

15

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22 September 2017

Yoshiaki Nishimura

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22 September 2017

Malcolm A Martin

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22 September 2017

language of work or name

English

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publication date

1 July 2015

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Science Translational Medicine

22 September 2017

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22 September 2017

7

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22 September 2017

298ra120

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22 September 2017

298

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Broadly neutralizing antibodies and the search for an HIV-1 vaccine: the end of the beginning

22 September 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Follicular helper CD4 T cells (TFH)

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

CD4 T follicular helper cell dynamics during SIV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Follicular helper T cells: lineage and location

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Molecular programming of B cell memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Pathogenicity and mucosal transmissibility of the R5-tropic simian/human immunodeficiency virus SHIV(AD8) in rhesus macaques: implications for use in vaccine studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Most rhesus macaques infected with the CCR5-tropic SHIV(AD8) generate cross-reactive antibodies that neutralize multiple HIV-1 strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Rapid development of glycan-specific, broad, and potent anti-HIV-1 gp120 neutralizing antibodies in an R5 SIV/HIV chimeric virus infected macaque

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Expansion of HIV-specific T follicular helper cells in chronic HIV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Plasma levels of soluble CD14 independently predict mortality in HIV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Late interleukin-6 escalates T follicular helper cell responses and controls a chronic viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Unique gene expression program of human germinal center T helper cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Cytokine-secreting follicular T cells shape the antibody repertoire

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Analysis of immunoglobulin transcripts and hypermutation following SHIV(AD8) infection and protein-plus-adjuvant immunization

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Single-cell and deep sequencing of IgG-switched macaque B cells reveal a diverse Ig repertoire following immunization

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

IMGT, the international ImMunoGeneTics information system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Breadth of human immunodeficiency virus-specific neutralizing activity in sera: clustering analysis and association with clinical variables

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Characteristics of the earliest cross-neutralizing antibody response to HIV-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Breadth of neutralizing antibody response to human immunodeficiency virus type 1 is affected by factors early in infection but does not influence disease progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Inadequate T follicular cell help impairs B cell immunity during HIV infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Neutralizing antibodies generated during natural HIV-1 infection: good news for an HIV-1 vaccine?

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

B cells in HIV infection and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Prevalence of broadly neutralizing antibody responses during chronic HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Clonal selection in the germinal centre by regulated proliferation and hypermutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

T-cell subsets in the germinal center.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Persistent antigen and germinal center B cells sustain T follicular helper cell responses and phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Bcl6 mediates the development of T follicular helper cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Human circulating PD-1+CXCR3-CXCR5+ memory Tfh cells are highly functional and correlate with broadly neutralizing HIV antibody responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Factors associated with the development of cross-reactive neutralizing antibodies during human immunodeficiency virus type 1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

HIV-1 neutralizing antibodies: understanding nature's pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Follicular B helper T cells in antibody responses and autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

T follicular helper cell dynamics in germinal centers

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Induction of ICOS+CXCR3+CXCR5+ TH cells correlates with antibody responses to influenza vaccination

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Human circulating influenza-CD4+ ICOS1+IL-21+ T cells expand after vaccination, exert helper function, and predict antibody responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Circulating precursor CCR7(lo)PD-1(hi) CXCR5⁺ CD4⁺ T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Loss of circulating CD4 T cells with B cell helper function during chronic HIV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Viral persistence redirects CD4 T cell differentiation toward T follicular helper cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Short- and long-term clinical outcomes in rhesus monkeys inoculated with a highly pathogenic chimeric simian/human immunodeficiency virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Characterization of stable, soluble trimers containing complete ectodomains of human immunodeficiency virus type 1 envelope glycoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

A method for identification of HIV gp140 binding memory B cells in human blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Tiered categorization of a diverse panel of HIV-1 Env pseudoviruses for assessment of neutralizing antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Isolation of antibody V(D)J sequences from single cell sorted rhesus macaque B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Somatic Populations of PGT135-137 HIV-1-Neutralizing Antibodies Identified by 454 Pyrosequencing and Bioinformatics

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

Clustal W and Clustal X version 2.0

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.AAB3964

10.1126/SCITRANSLMED.AAB3964

21 January 2018

Identifiers

DOI

1 reference

22 September 2017

1 reference