The Src-selective kinase inhibitor PP1 also inhibits Kit and Bcr-Abl tyrosine kinases (Q40684182)

22 September 2017

title

The Src-selective kinase inhibitor PP1 also inhibits Kit and Bcr-Abl tyrosine kinases (English)

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22 September 2017

Louise Tatton

1

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22 September 2017

Gary M Morley

series ordinal

2

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22 September 2017

Rajesh Chopra

series ordinal

3

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22 September 2017

Asim Khwaja

series ordinal

4

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22 September 2017

language of work or name

English

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publication date

9 December 2002

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Journal of Biological Chemistry

22 September 2017

published in

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22 September 2017

volume

278

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22 September 2017

issue

7

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22 September 2017

page(s)

4847-4853

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Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

22 September 2017

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Evidence that Src-type tyrosine kinase activity is necessary for initiation of calcium release at fertilization in sea urchin eggs

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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CHK down-regulates SCF/KL-activated Lyn kinase activity in Mo7e megakaryocytic cells.

21 January 2018

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SU6656, a selective src family kinase inhibitor, used to probe growth factor signaling

21 January 2018

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21 January 2018

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The c-KIT mutation causing human mastocytosis is resistant to STI571 and other KIT kinase inhibitors; kinases with enzymatic site mutations show different inhibitor sensitivity profiles than wild-type kinases and those with regulatory-type mutations

21 January 2018

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Substitution of an aspartic acid results in constitutive activation of c-kit receptor tyrosine kinase in a rat tumor mast cell line RBL-2H3

21 January 2018

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A dual inhibitor of platelet-derived growth factor beta-receptor and Src kinase activity potently interferes with motogenic and mitogenic responses to PDGF in vascular smooth muscle cells. A novel candidate for prevention of vascular remodeling

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Identification of activating c-kit mutations in adult-, but not in childhood-onset indolent mastocytosis: a possible explanation for divergent clinical behavior

21 January 2018

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High frequency of point mutations clustered within the adenosine triphosphate-binding region of BCR/ABL in patients with chronic myeloid leukemia or Ph-positive acute lymphoblastic leukemia who develop imatinib (STI571) resistance

21 January 2018

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Perspectives on the development of a molecularly targeted agent

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M209321200

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22 September 2017

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