The biology of stem cell factor and its receptor C-kit (Q33785129)

29 July 2017

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title

The biology of stem cell factor and its receptor C-kit (English)

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29 July 2017

Ashman LK

1

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29 July 2017

1 October 1999

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International Journal of Biochemistry & Cell Biology

29 July 2017

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29 July 2017

31

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29 July 2017

10

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29 July 2017

1037-1051

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In vitro duplication and ‘cure’ of haemopoietic defects in genetically anaemic mice

29 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

A murine monoclonal antibody specific for a cell-surface antigen expressed by a subgroup of human myeloid leukaemias

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

A monoclonal antibody to a human mast cell/myeloid leukaemia-specific antigen binds to normal haemopoietic progenitor cells and inhibits colony formation in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Specificity of a mouse monoclonal antibody raised against acute myeloid leukaemia cells for mast cells in human mucosal and connective tissues.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

A monoclonal antibody that inhibits the action of GM-CSF on normal but not leukaemic progenitors

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https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

The dominant-white spotting (W) locus of the mouse encodes the c-kit proto-oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

A new acute transforming feline retrovirus and relationship of its oncogene v-kit with the protein kinase gene family.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Primary structure of c-kit: relationship with the CSF-1/PDGF receptor kinase family--oncogenic activation of v-kit involves deletion of extracellular domain and C terminus.

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https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Steel locus defines new multipotent growth factor

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https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

c-kit protein, a transmembrane kinase: identification in tissues and characterization

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Expression of c-kit gene products in known cellular targets of W mutations in normal and W mutant mice--evidence for an impaired c-kit kinase in mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Expression of c-kit and kit ligand proteins in normal human tissues

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

The c-kit-encoded tyrosine kinase regulates the proliferation of early pre-B cells

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https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Intrathymically expressed c-kit ligand (stem cell factor) is a major factor driving expansion of very immature thymocytes in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Expression and function of c-kit in hemopoietic progenitor cells

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https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Expression of a functional c-kit receptor on a subset of natural killer cells

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https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Cloning and functional analysis of the mouse c-kit promoter.

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https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Characterization of the promoter region of the human c-kit proto-oncogene

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https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Inactivation of a c-Myb/estrogen receptor fusion protein in transformed primary cells leads to granulocyte/macrophage differentiation and down regulation of c-kit but not c-myc or cdc2.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Transcription factor SCL is required for c-kit expression and c-Kit function in hemopoietic cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Loss of AP-2 results in downregulation of c-KIT and enhancement of melanoma tumorigenicity and metastasis.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

The Wsh and Ph mutations affect the c-kit expression profile: c-kit misexpression in embryogenesis impairs melanogenesis in Wsh and Ph mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Modulation of c-kit mRNA and protein by hemopoietic growth factors

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Transforming growth factor-beta: a bidirectional regulator of hematopoietic cell growth

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Differential expression and processing of two cell associated forms of the kit-ligand: KL-1 and KL-2

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

In vitro duplication and in vivo cure of mast-cell deficiency of Sl/Sld mutant mice by cloned 3T3 fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Support of human hematopoiesis in long-term bone marrow cultures by murine stromal cells selectively expressing the membrane-bound and secreted forms of the human homolog of the steel gene product, stem cell factor

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Consequences of exclusive expression in vivo of Kit-ligand lacking the major proteolytic cleavage site

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Chymase cleavage of stem cell factor yields a bioactive, soluble product

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Developmental abnormalities in Steel17H mice result from a splicing defect in the steel factor cytoplasmic tail

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Role of dimerization of the membrane-associated growth factor kit ligand in juxtacrine signaling: the Sl17H mutation affects dimerization and stability-phenotypes in hematopoiesis.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

The c-kit ligand suppresses apoptosis of human natural killer cells through the upregulation of bcl-2.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

The kit receptor promotes cell survival via activation of PI 3-kinase and subsequent Akt-mediated phosphorylation of Bad on Ser136

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Functional interaction of erythropoietin and stem cell factor receptors is essential for erythroid colony formation

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

c-kit ligand: a unique potentiator of mediator release by human lung mast cells

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Adhesion of mouse mast cells to fibroblasts: adverse effects of steel (Sl) mutation

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Cytokines increase human hemopoietic cell adhesiveness by activation of very late antigen (VLA)-4 and VLA-5 integrins

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Tyrosine kinase-deficient Wv c-kit induces mast cell adhesion and chemotaxis

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Stem cell factor enhances the adhesion of AML cells to fibronectin and augments fibronectin-mediated anti-apoptotic and proliferative signals

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https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Effects of mutant c-Kit in early myeloid cells

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https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Lyn associates with the juxtamembrane region of c-Kit and is activated by stem cell factor in hematopoietic cell lines and normal progenitor cells

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Progression of human cutaneous melanoma is associated with loss of expression of c-kit proto-oncogene receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Identification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorder

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Exon skipping by mutation of an authentic splice site of c-kit gene in W/W mouse

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Alternate splicing creates two forms of the human kit protein.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Differential roles of PI3-kinase and Kit tyrosine 821 in Kit receptor-mediated proliferation, survival and cell adhesion in mast cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Elevated expression of the proto-oncogene c-kit in patients with mastocytosis

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Primary structure and functional expression of rat and human stem cell factor DNAs

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Transformation of NIH3T3 fibroblasts by the c-Kit receptor tyrosine kinase: effect of receptor density and ligand-requirement

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Characterization of a fusion protein composed of the extracellular domain of c-kit and the Fc region of human IgG expressed in a baculovirus system

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

The majority of stem cell factor exists as monomer under physiological conditions. Implications for dimerization mediating biological activity

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Soluble c‐kit molecule in serum from healthy individuals and patients with haemopoietic disorders

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https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Soluble c-kit levels in acute GVHD after allogeneic bone marrow transplantation

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https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Low levels of serum soluble c-kit relates to delayed engraftment after bone marrow transplantation

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Expression and identification of aberrant c-kit transcripts in human cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Involvement of phospholipase Cgamma1 in mouse egg activation induced by a truncated form of the C-kit tyrosine kinase present in spermatozoa.

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

Isoforms of c-KIT differ in activation of signalling pathways and transformation of NIH3T3 fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1357-2725%2899%2900076-X

7 January 2021

10.1016/S1357-2725(99)00076-X

Identifiers

DOI

1 reference

29 July 2017

1 reference

PubMed ID

10582338