Progranulin Plays a Central Role in Host Defense during Sepsis by Promoting Macrophage Recruitment (Q40686335)

22 September 2017

Progranulin Plays a Central Role in Host Defense during Sepsis by Promoting Macrophage Recruitment (English)

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22 September 2017

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Zhixin Song

1

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22 September 2017

Xuemei Zhang

2

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22 September 2017

Liping Zhang

3

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22 September 2017

Fang Xu

4

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22 September 2017

Xintong Tao

5

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22 September 2017

Hua Zhang

6

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22 September 2017

Xue Lin

7

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22 September 2017

Lihua Kang

8

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22 September 2017

Yu Xiang

9

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22 September 2017

Xaiofei Lai

10

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22 September 2017

Qun Zhang

11

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22 September 2017

Kun Huang

12

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22 September 2017

Yubing Dai

13

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22 September 2017

Yibing Yin

14

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22 September 2017

Ju Cao

15

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22 September 2017

language of work or name

English

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publication date

5 May 2016

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American Journal of Respiratory and Critical Care Medicine

22 September 2017

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22 September 2017

194

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22 September 2017

1219-1232

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22 September 2017

10

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Immunotherapy for the Adjunctive Treatment of Sepsis: From Immunosuppression to Immunostimulation. Time for a Paradigm Change?

22 September 2017

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

Assessment of Global Incidence and Mortality of Hospital-treated Sepsis. Current Estimates and Limitations

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

Hospitalization Type and Subsequent Severe Sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

New approaches to the study of sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

Modulation of TNF-α mRNA stability by human antigen R and miR181s in sepsis-induced immunoparalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

Developing a clinically feasible personalized medicine approach to pediatric septic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

Triggering receptor expressed on myeloid cells-2 protects against polymicrobial sepsis by enhancing bacterial clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

Nonredundant protective properties of FPR2/ALX in polymicrobial murine sepsis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

Interleukin 5 is protective during sepsis in an eosinophil-independent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

IL-27 controls sepsis-induced impairment of lung antibacterial host defence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

Insights into the role of progranulin in immunity, infection, and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

Progranulin enhances neural progenitor cell proliferation through glycogen synthase kinase 3β phosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

Conversion of proepithelin to epithelins: roles of SLPI and elastase in host defense and wound repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and enhance neuronal survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

PGRN is a key adipokine mediating high fat diet-induced insulin resistance and obesity through IL-6 in adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

Structure, function, and mechanism of progranulin; the brain and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

Progranulin expression in advanced human atherosclerotic plaque

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

Progranulin is a mediator of the wound response

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

Granulin is a soluble cofactor for toll-like receptor 9 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

Serum progranulin levels are elevated in patients with systemic lupus erythematosus, reflecting disease activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

Type I interferons in infectious disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

Activation of IL-27 signalling promotes development of postinfluenza pneumococcal pneumonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

α-Hemolysin activity of methicillin-susceptible Staphylococcus aureus predicts ventilator-associated pneumonia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

Type I interferon signaling in hematopoietic cells is required for survival in mouse polymicrobial sepsis by regulating CXCL10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

Circulating PGRN is significantly associated with systemic insulin sensitivity and autophagic activity in metabolic syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

Serum progranulin levels are elevated in dermatomyositis patients with acute interstitial lung disease, predicting prognosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

Serum progranulin concentrations may be associated with macrophage infiltration into omental adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

PGRN protects against colitis progression in mice in an IL-10 and TNFR2 dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

CC chemokine receptor 2 regulates leukocyte recruitment and IL-10 production during acute polymicrobial sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

Important role for CC chemokine ligand 2-dependent lung mononuclear phagocyte recruitment to inhibit sepsis in mice infected with Streptococcus pneumoniae

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

Macrophage migration inhibitory factor promotes clearance of pneumococcal colonization

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

Toll-like receptor 9 inhibition reduces mortality in polymicrobial sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

Endothelial progenitor cells and a stromal cell-derived factor-1α analogue synergistically improve survival in sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

Progranulin protects against osteoarthritis through interacting with TNF-α and β-Catenin signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

A molecular biomarker to diagnose community-acquired pneumonia on intensive care unit admission

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

Progranulin is a substrate for neutrophil-elastase and proteinase-3 in the airway and its concentration correlates with mediators of airway inflammation in COPD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1164%2FRCCM.201601-0056OC

10.1164/RCCM.201601-0056OC

21 January 2018

Identifiers

DOI

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22 September 2017

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