Regulation of the pdx1 gene promoter in pancreatic beta-cells (Q40689339)

22 September 2017

Regulation of the pdx1 gene promoter in pancreatic beta-cells (English)

1 reference

22 September 2017

Susan C Campbell

1

1 reference

PubMed ID

12437983

22 September 2017

Wendy M Macfarlane

series ordinal

2

1 reference

22 September 2017

1 November 2002

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Biochemical and Biophysical Research Communications

22 September 2017

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22 September 2017

299

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22 September 2017

2

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22 September 2017

277-284

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The pancreatic homeodomain transcription factor IDX1/IPF1 is expressed in neural cells during brain development.

22 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

Nutrient regulation of insulin gene expression.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

Induction of insulin and islet amyloid polypeptide production in pancreatic islet glucagonoma cells by insulin promoter factor 1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

Glucose regulates islet amyloid polypeptide gene transcription in a PDX1- and calcium-dependent manner

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

The human glucokinase gene beta-cell-type promoter: an essential role of insulin promoter factor 1/PDX-1 in its activation in HIT-T15 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

Early-onset type-II diabetes mellitus (MODY4) linked to IPF1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

Pancreatic islet expression of the homeobox factor STF-1 relies on an E-box motif that binds USF.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

Hepatocyte nuclear factor 3beta is involved in pancreatic beta-cell-specific transcription of the pdx-1 gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

The hepatocyte nuclear factor 3 (HNF3 or FOXA) family in metabolism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

Hormonal regulation of an islet-specific enhancer in the pancreatic homeobox gene STF-1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

Pancreatic beta cell-specific transcription of the pdx-1 gene. The role of conserved upstream control regions and their hepatic nuclear factor 3beta sites.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

Functional conservation of regulatory elements in the pdx-1 gene: PDX-1 and hepatocyte nuclear factor 3beta transcription factors mediate beta-cell-specific expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

The role of hepatic nuclear factor 1 alpha and PDX-1 in transcriptional regulation of the pdx-1 gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

Conserved sequences in a tissue-specific regulatory region of the pdx-1 gene mediate transcription in Pancreatic beta cells: role for hepatocyte nuclear factor 3 beta and Pax6

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

A pancreatic beta -cell-specific enhancer in the human PDX-1 gene is regulated by hepatocyte nuclear factor 3beta (HNF-3beta ), HNF-1alpha, and SPs transcription factors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

Impaired expression of transcription factor IUF1 in a pancreatic beta-cell line derived from a patient with persistent hyperinsulinaemic hypoglycaemia of infancy (nesidioblastosis).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

Glucagon-like peptide-1: a major regulator of pancreatic beta-cell function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

Mutation in hepatocyte nuclear factor-1 beta gene (TCF2) associated with MODY.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

The p38/reactivating kinase mitogen-activated protein kinase cascade mediates the activation of the transcription factor insulin upstream factor 1 and insulin gene transcription by high glucose in pancreatic beta-cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

Glucose stimulates translocation of the homeodomain transcription factor PDX1 from the cytoplasm to the nucleus in pancreatic beta-cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

Glucose stimulates the activation domain potential of the PDX-1 homeodomain transcription factor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

Purification of the beta-cell glucose-sensitive factor that transactivates the insulin gene differentially in normal and transformed islet cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

Reduction of insulin gene transcription in HIT-T15 beta cells chronically exposed to a supraphysiologic glucose concentration is associated with loss of STF-1 transcription factor expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

Glucagon-like peptide-1 affects gene transcription and messenger ribonucleic acid stability of components of the insulin secretory system in RIN 1046-38 cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

Glucagon-like peptide-1 can reverse the age-related decline in glucose tolerance in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

Glucagon-like peptide-1 regulates the beta cell transcription factor, PDX-1, in insulinoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

Cloning and functional expression of the human islet GLP-1 receptor. Demonstration that exendin-4 is an agonist and exendin-(9-39) an antagonist of the receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

Exocytosis of insulin promotes insulin gene transcription via the insulin receptor/PI-3 kinase/p70 s6 kinase and CaM kinase pathways.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

Mechanisms of nuclear signalling by vitamin D3. Interplay with retinoid and thyroid hormone signalling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

Inhibitory effects of streptozotocin, tumor necrosis factor-alpha, and interleukin-1beta on glucokinase activity in pancreatic islets and gene expression of GLUT2 and glucokinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

TNFalpha and leptin inhibit basal and glucose-stimulated insulin secretion and gene transcription in the HIT-T15 pancreatic cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

Induction of heparin-binding EGF-like growth factor expression during myogenesis. Activation of the gene by MyoD and localization of the transmembrane form of the protein on the myotube surface

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

Expression of heparin-binding epidermal growth factor-like growth factor during pancreas development. A potential role of PDX-1 in transcriptional activation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-291X%2802%2902633-5

10.1016/S0006-291X(02)02633-5

7 January 2021

Identifiers

DOI

1 reference

release_lk6yjjzyjjap5lytwkp6kgft2i

22 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/lk6yjjzyjjap5lytwkp6kgft2i

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

12437983

1 reference

PubMed ID

12437983