Acute mitochondrial and chronic toxicological effects of 1-methyl-4-phenylpyridinium in human neuroblastoma cells (Q40690704)

22 September 2017

title

Acute mitochondrial and chronic toxicological effects of 1-methyl-4-phenylpyridinium in human neuroblastoma cells (English)

1 reference

22 September 2017

1 reference

Stacy E Stephans

1

1 reference

22 September 2017

Gary W Miller

series ordinal

2

1 reference

22 September 2017

Allan I Levey

series ordinal

3

1 reference

22 September 2017

J Timothy Greenamyre

series ordinal

4

1 reference

22 September 2017

publication date

1 October 2002

1 reference

22 September 2017

1 reference

22 September 2017

volume

23

1 reference

22 September 2017

issue

4-5

1 reference

22 September 2017

page(s)

569-580

1 reference

A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

22 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

Glucose protection from MPP+-induced apoptosis depends on mitochondrial membrane potential and ATP synthase

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

Dopaminergic cell death induced by MPP(+), oxidant and specific neurotoxicants shares the common molecular mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

The dopamine transporter: immunochemical characterization and localization in brain

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

Irreversible inhibition of mitochondrial complex I by 1-methyl-4-phenylpyridinium: evidence for free radical involvement

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

Uptake and accumulation of 1-methyl-4-phenylpyridinium by rat liver mitochondria measured using an ion-selective electrode

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

Dopamine transporter is required for in vivo MPTP neurotoxicity: evidence from mice lacking the transporter.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

Inhibition of neuronal nitric oxide synthase prevents MPTP-induced parkinsonism in baboons.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

Protection against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine by monoamine oxidase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

[3H]dihydrorotenone binding to NADH: ubiquinone reductase (complex I) of the electron transport chain: an autoradiographic study.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

Nitric oxide synthase and neuronal vulnerability in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

Reduced levels of catalase activity potentiate MPP+-induced toxicity: comparison between MN9D cells and CHO cells

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

Parkinsonism-inducing neurotoxin MPP+: uptake and toxicity in nonneuronal COS cells expressing dopamine transporter cDNA

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

Evidence that the blockade of mitochondrial respiration by the neurotoxin 1-methyl-4-phenylpyridinium (MPP+) involves binding at the same site as the respiratory inhibitor, rotenone

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

Distinct mechanisms underlie neurotoxin-mediated cell death in cultured dopaminergic neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

Dopamine but not norepinephrine or serotonin uptake inhibitors protect mice against neurotoxicity of MPTP.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

Immunochemical analysis of dopamine transporter protein in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

Dopamine transporters and neuronal injury

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

The selective toxicity of 1-methyl-4-phenylpyridinium to dopaminergic neurons: the role of mitochondrial complex I and reactive oxygen species revisited.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

Mitochondrial calcium transport

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

The light-addressable potentiometric sensor: principles and biological applications

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

Dopamine transporter expression confers cytotoxicity to low doses of the parkinsonism-inducing neurotoxin 1-methyl-4-phenylpyridinium.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

Effects of excitotoxin exposure on metabolic rate of primary hippocampal cultures: application of silicon microphysiometry to neurobiology

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

Inhibition of mitochondrial NADH dehydrogenase by pyridine derivatives and its possible relation to experimental and idiopathic parkinsonism

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

Reduction of MPP(+)-induced hydroxyl radical formation and nigrostriatal MPTP toxicity by inhibiting nitric oxide synthase.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

MPP+ inhibits proliferation of PC12 cells by a p21(WAF1/Cip1)-dependent pathway and induces cell death in cells lacking p21(WAF1/Cip1)

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

1-Methyl-4-phenylpyridinium produces excitotoxic lesions in rat striatum as a result of impairment of oxidative metabolism.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

Protection of substantia nigra from MPP+ neurotoxicity by N-methyl-D-aspartate antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

1 reference

7 January 2021

Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

Studies on the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: inhibition of NAD-linked substrate oxidation by its metabolite, 1-methyl-4-phenylpyridinium

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

MK-801 prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in primates

1 reference

https://api.crossref.org/works/10.1016%2FS0161-813X%2802%2900060-8

7 January 2021

10.1016/S0161-813X(02)00060-8

Identifiers

DOI

1 reference

release_zz6avvi6qnab7aajys4lzhowfa

22 September 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/zz6avvi6qnab7aajys4lzhowfa

24 November 2022

mapped directly with Wikidata item

1 reference