The HIV-1 Nef protein and phagocyte NADPH oxidase activation (Q40703608)

22 September 2017

The HIV-1 Nef protein and phagocyte NADPH oxidase activation (English)

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22 September 2017

1

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22 September 2017

5

Maciej Wiznerowicz

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22 September 2017

Olivier Plastre

2

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22 September 2017

Makoto Sawada

3

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22 September 2017

Kazuo Suzuki

4

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22 September 2017

Etsuko Kiyokawa

6

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22 September 2017

Didier Trono

7

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22 September 2017

Karl-Heinz Krause

8

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22 September 2017

language of work or name

English

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publication date

30 August 2002

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Journal of Biological Chemistry

22 September 2017

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22 September 2017

277

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22 September 2017

42136-42143

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22 September 2017

44

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Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection

22 September 2017

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https://api.crossref.org/works/10.1074%2FJBC.M200862200

Structure--function relationships in HIV-1 Nef.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M200862200

The numerous effector functions of Nef.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M200862200

CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

HIV-1 Nef mediates lymphocyte chemotaxis and activation by infected macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

The HIV Nef protein alters Ca(2+) signaling in myelomonocytic cells through SH3-mediated protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

Interleukin 10 is induced by recombinant HIV-1 Nef protein involving the calcium/calmodulin-dependent phosphodiesterase signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

Induction of activator protein 1 (AP-1) in macrophages by human immunodeficiency virus type-1 NEF is a cell-type-specific response that requires both hck and MAPK signaling events

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

Detection of AIDS virus in macrophages in brain tissue from AIDS patients with encephalopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

Measurement and characterization of superoxide generation in microglial cells: evidence for an NADPH oxidase-dependent pathway.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M200862200

Two cytosolic components of the human neutrophil respiratory burst oxidase translocate to the plasma membrane during cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

Mechanism for phosphorylation-induced activation of the phagocyte NADPH oxidase protein p47(phox). Triple replacement of serines 303, 304, and 328 with aspartates disrupts the SH3 domain-mediated intramolecular interaction in p47(phox), thereby acti

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

Assembly of the neutrophil respiratory burst oxidase: a direct interaction between p67PHOX and cytochrome b558.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

Regulation of phagocyte oxygen radical production by the GTP-binding protein Rac 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

Molecular basis for Rac2 regulation of phagocyte NADPH oxidase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M200862200

Differentiated regulation of allo-antigen presentation by different types of murine microglial cell lines

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M200862200

Serial analysis of gene expression in a microglial cell line

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M200862200

Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M200862200

Mutational analysis of HIV-1 Nef: identification of two mutants that are temperature-sensitive for CD4 downregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

Chemoattractant-induced respiratory burst: increases in cytosolic Ca2+ concentrations are essential and synergize with a kinetically distinct second signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

Stimulation of the NADPH oxidase in activated rat microglia removes nitric oxide but induces peroxynitrite production

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

A conserved domain and membrane targeting of Nef from HIV and SIV are required for association with a cellular serine kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

Isoprenoid metabolism is required for stimulation of the respiratory burst oxidase of HL-60 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

Rho proteins: targets for bacterial toxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

Regulatory and signaling properties of the Vav family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M200862200

The cytotoxic necrotizing factor 1 (CNF1) from Escherichia coli

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M200862200

p21-activated kinase 1 plays a critical role in cellular activation by Nef.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

How Vav proteins discriminate the GTPases Rac1 and RhoA from Cdc42.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

CDC42 and Rac1 are implicated in the activation of the Nef-associated kinase and replication of HIV-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

Activation of p47(PHOX), a cytosolic subunit of the leukocyte NADPH oxidase. Phosphorylation of ser-359 or ser-370 precedes phosphorylation at other sites and is required for activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

Regulation of human leukocyte p21-activated kinases through G protein--coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

Cryptic Rac-binding and p21(Cdc42Hs/Rac)-activated kinase phosphorylation sites of NADPH oxidase component p67(phox)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

HIV-1 Nef associated PAK and PI3-kinases stimulate Akt-independent Bad-phosphorylation to induce anti-apoptotic signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

The PX domains of p47phox and p40phox bind to lipid products of PI(3)K

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

The insert region of Rac1 is essential for membrane ruffling but not cellular transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

Regulation of reactive-oxygen-species generation in fibroblasts by Rac1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

Rac1, and not Rac2, is involved in the regulation of the intracellular hydrogen peroxide level in HepG2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

A Rac1 effector site controlling mitogenesis through superoxide production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

Rac activation induces NADPH oxidase activity in transgenic COSphox cells, and the level of superoxide production is exchange factor-dependent.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

Neutrophils exposed to bacterial lipopolysaccharide upregulate NADPH oxidase assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M200862200

21 January 2018

Identifiers

DOI

10.1074/JBC.M200862200

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22 September 2017

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