Binding of JNK/SAPK to MEKK1 is regulated by phosphorylation (Q40704480)

22 September 2017

Binding of JNK/SAPK to MEKK1 is regulated by phosphorylation (English)

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22 September 2017

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5

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22 September 2017

Ewen D Gallagher

1

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22 September 2017

Shuichan Xu

series ordinal

2

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22 September 2017

Carolyn Moomaw

series ordinal

3

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22 September 2017

Clive A Slaughter

series ordinal

4

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22 September 2017

language of work or name

English

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publication date

12 September 2002

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Journal of Biological Chemistry

22 September 2017

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22 September 2017

277

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22 September 2017

48

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22 September 2017

45785-45792

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https://api.crossref.org/works/10.1074%2FJBC.M207702200

22 September 2017

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Pheromone response, mating and cell biology

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M207702200

A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

MEKKs, GCKs, MLKs, PAKs, TAKs, and tpls: upstream regulators of the c-Jun amino-terminal kinases?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

The Ste20 group kinases as regulators of MAP kinase cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

Signal transduction by the JNK group of MAP kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

MEKK1 binds directly to the c-Jun N-terminal kinases/stress-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

JNKK1 organizes a MAP kinase module through specific and sequential interactions with upstream and downstream components mediated by its amino-terminal extension

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

MEK kinase 1 (MEKK1) transduces c-Jun NH2-terminal kinase activation in response to changes in the microtubule cytoskeleton.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

MEKK1 binds raf-1 and the ERK2 cascade components

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

The PHD domain of MEKK1 acts as an E3 ubiquitin ligase and mediates ubiquitination and degradation of ERK1/2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

NIK is a new Ste20-related kinase that binds NCK and MEKK1 and activates the SAPK/JNK cascade via a conserved regulatory domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

Tumor necrosis factor signaling to stress-activated protein kinase (SAPK)/Jun NH2-terminal kinase (JNK) and p38. Germinal center kinase couples TRAF2 to mitogen-activated protein kinase/ERK kinase kinase 1 and SAPK while receptor interacting [...]

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

Direct activation of mitogen-activated protein kinase kinase kinase MEKK1 by the Ste20p homologue GCK and the adapter protein TRAF2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

HTLV-I Tax protein binds to MEKK1 to stimulate IkappaB kinase activity and NF-kappaB activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

14-3-3 proteins interact with specific MEK kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

p115 Rho GTPase activating protein interacts with MEKK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

Scaffolding and protein interactions in MAP kinase modules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

A conserved negative regulatory region in alphaPAK: inhibition of PAK kinases reveals their morphological roles downstream of Cdc42 and Rac1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

Activation of mitogen-activated protein kinase cascades by p21-activated protein kinases in cell-free extracts of Xenopus oocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

Dimer formation by ternary complex factor ELK-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

Cloning of rat MEK kinase 1 cDNA reveals an endogenous membrane-associated 195-kDa protein with a large regulatory domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

The Elk-1 ETS-domain transcription factor contains a mitogen-activated protein kinase targeting motif.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

Docking domains and substrate-specificity determination for MAP kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

Hydrophobic as well as charged residues in both MEK1 and ERK2 are important for their proper docking

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

Crystal structures of MAP kinase p38 complexed to the docking sites on its nuclear substrate MEF2A and activator MKK3b

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

A conserved docking motif in MAP kinases common to substrates, activators and regulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

Two co-existing mechanisms for nuclear import of MAP kinase: passive diffusion of a monomer and active transport of a dimer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

Evidence that inactive p42 mitogen-activated protein kinase and inactive Rsk exist as a heterodimer in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

PTP-SL and STEP protein tyrosine phosphatases regulate the activation of the extracellular signal-regulated kinases ERK1 and ERK2 by association through a kinase interaction motif.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

A novel regulatory mechanism of MAP kinases activation and nuclear translocation mediated by PKA and the PTP-SL tyrosine phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

p21-activated Protein Kinase γ-PAK Is Activated by Ionizing Radiation and Other DNA-damaging Agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

Paclitaxel (Taxol)-induced gene expression and cell death are both mediated by the activation of c-Jun NH2-terminal kinase (JNK/SAPK)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

Phosphatidylinositol 3-kinase regulates Raf1 through Pak phosphorylation of serine 338

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

Structural Analysis of the MAP Kinase ERK2 and Studies of MAP Kinase Regulatory Pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

Regulation of the activity of MEK kinase 1 (MEKK1) by autophosphorylation within the kinase activation domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

Stress pathway activation induces phosphorylation of retinoid X receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207702200

21 January 2018

Identifiers

DOI

10.1074/JBC.M207702200

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release_xbc5mahkindddbxfvzyzpqoucm

22 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/xbc5mahkindddbxfvzyzpqoucm

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference