Cellular effects of CPT-11 on colon carcinoma cells: dependence on p53 and hMLH1 status (Q40706999)

22 September 2017

Cellular effects of CPT-11 on colon carcinoma cells: dependence on p53 and hMLH1 status (English)

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22 September 2017

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Roberta Magrini

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22 September 2017

Mandar R Bhonde

2

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22 September 2017

Marie-Luise Hanski

3

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22 September 2017

Michael Notter

4

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22 September 2017

Hans Scherübl

5

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22 September 2017

C Richard Boland

6

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22 September 2017

Martin Zeitz

7

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22 September 2017

Christoph Hanski

8

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22 September 2017

language of work or name

English

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publication date

1 September 2002

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International Journal of Cancer

22 September 2017

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22 September 2017

101

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22 September 2017

23-31

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22 September 2017

1

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Irinotecan in the treatment of colorectal cancer: clinical overview

22 September 2017

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Cellular interactions of 5-fluorouracil and the camptothecin analogue CPT-11 (irinotecan) in a human colorectal carcinoma cell line

21 January 2018

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P53 status plays no role in radiosensitizing effects of SN-38, a camptothecin derivative

21 January 2018

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Induction of p53-dependent and p53-independent cellular responses by topoisomerase 1 inhibitors

21 January 2018

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Sensitivity to CPT-11 of xenografted human colorectal cancers as a function of microsatellite instability and p53 status.

21 January 2018

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Alteration of drug chemosensitivity caused by the adenovirus-mediated transfer of the wild-type p53 gene in human lung cancer cells

21 January 2018

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The "comparative growth assay": examining the interplay of anti-cancer agents with cells carrying single gene alterations

21 January 2018

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Resistance to topoisomerase poisons due to loss of DNA mismatch repair

21 January 2018

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Requirement for p53 and p21 to sustain G2 arrest after DNA damage

21 January 2018

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Determinants of CPT-11 and SN-38 activities in human lung cancer cells

21 January 2018

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Combination of irinotecan (CPT11) and 5-fluorouracil with an analysis of cellular determinants of drug activity

21 January 2018

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Mechanisms of G2 arrest in response to overexpression of p53

21 January 2018

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Competency in mismatch repair prohibits clonal expansion of cancer cells treated with N-methyl-N'-nitro-N-nitrosoguanidine

21 January 2018

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14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage

21 January 2018

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Schedule-dependent cytotoxicity of SN-38 in p53 wild-type and mutant colon adenocarcinoma cell lines

21 January 2018

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Activation of the Fas pathway independently of Fas ligand during apoptosis induced by camptothecin in p53 mutant human colon carcinoma cells

21 January 2018

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Apoptosis of lung cancer cells caused by some anti-cancer agents (MMC, CPT-11, ADM) is inhibited by bcl-2.

21 January 2018

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Repair of double-strand breaks by homologous recombination in mismatch repair-defective mammalian cells

21 January 2018

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p21 Inhibits Thr161Phosphorylation of Cdc2 to Enforce the G2DNA Damage Checkpoint

21 January 2018

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Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21

21 January 2018

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Randomised trial of irinotecan plus supportive care versus supportive care alone after fluorouracil failure for patients with metastatic colorectal cancer

21 January 2018

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Irinotecan (CPT-11) in patients with advanced colorectal cancer previously treated with 5-fluorouracil-based chemotherapy

21 January 2018

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CPT-11 in human colon-cancer cell lines and xenografts: characterization of cellular sensitivity determinants

21 January 2018

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Ectopic p16(ink4) expression enhances CPT-11-induced apoptosis through increased delay in S-phase progression in human non-small-cell-lung-cancer cells

21 January 2018

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Apoptosis in small intestinal epithelial from p53-null mice: evidence for a delayed, p53-independent G2/M-associated cell death after gamma-irradiation

21 January 2018

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Cell-cycle arrest versus cell death in cancer therapy

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IJC.10565

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22 September 2017

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