Cellular interactions of 5-fluorouracil and the camptothecin analogue CPT-11 (irinotecan) in a human colorectal carcinoma cell line (Q41056508)

26 September 2017

title

Cellular interactions of 5-fluorouracil and the camptothecin analogue CPT-11 (irinotecan) in a human colorectal carcinoma cell line (English)

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26 September 2017

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S Guichard

1

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26 September 2017

I Hennebelle

series ordinal

2

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26 September 2017

R Bugat

series ordinal

3

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26 September 2017

P Canal

series ordinal

4

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26 September 2017

language of work or name

English

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publication date

1 March 1998

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26 September 2017

published in

Biochemical Pharmacology

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26 September 2017

volume

55

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26 September 2017

issue

5

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26 September 2017

page(s)

667-676

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https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900541-8

26 September 2017

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Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata1,2

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CPT-11 (Irinotecan) in the treatment of colorectal cancer

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DNA topoisomerase I--targeted chemotherapy of human colon cancer in xenografts

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Synthesis of water-soluble (aminoalkyl)camptothecin analogs: inhibition of topoisomerase I and antitumor activity

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Phase II trial of irinotecan in patients with progressive or rapidly recurrent colorectal cancer.

7 January 2021

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Phase II study of irinotecan in the treatment of advanced colorectal cancer in chemotherapy-naive patients and patients pretreated with fluorouracil-based chemotherapy

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On the mechanism of topoisomerase I inhibition by camptothecin: evidence for binding to an enzyme-DNA complex

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Camptothecin, a specific inhibitor of type I DNA topoisomerase, induces DNA breakage at replication forks

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Clinical pharmacology of 5-fluorouracil

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Fluorouracil in colorectal cancer--a tale of two drugs: implications for biochemical modulation

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Effects of CPT-11 in combination with other anti-cancer agents in culture

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Simultaneous determination of the camptothecin analogue CPT-11 and its active metabolite SN-38 by high-performance liquid chromatography: application to plasma pharmacokinetic studies in cancer patients

7 January 2021

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Reversed-phase high-performance liquid chromatographic method for the simultaneous quantitation of the carboxylate and lactone forms of the camptothecin derivative irinotecan, CPT-11, and its metabolite SN-38 in plasma

7 January 2021

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A role for dihydropyrimidine dehydrogenase and thymidylate synthase in tumour sensitivity to fluorouracil

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Irinotecan is an active agent in untreated patients with metastatic colorectal cancer

7 January 2021

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Phase I clinical and pharmacokinetic study of irinotecan, fluorouracil, and leucovorin in patients with advanced solid tumors

7 January 2021

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CPT-11 (irinotecan) and 5-fluorouracil: a promising combination for therapy of colorectal cancer

7 January 2021

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Aberrant cell cycle inhibition pattern in human colon carcinoma cell lines after exposure to 5-fluorouracil

7 January 2021

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Do antimetabolites interfere with the glycosylation of cellular glycoconjugates?

7 January 2021

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Comparison of topoisomerase I inhibition, DNA damage, and cytotoxicity of camptothecin derivatives presently in clinical trials

7 January 2021

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Differential stabilization of eukaryotic DNA topoisomerase I cleavable complexes by camptothecin derivatives

7 January 2021

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DNA topoisomerases and DNA repair

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Studies on the role of topoisomerases in general, gene- and strand-specific DNA repair

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Effects of uracil incorporation, DNA mismatches, and abasic sites on cleavage and religation activities of mammalian topoisomerase I.

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10.1016/S0006-2952(97)00541-8

7 January 2021

Identifiers

DOI

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26 September 2017

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