Ubiquitin-independent function of optineurin in autophagic clearance of protein aggregates (Q40710483)

23 September 2017

Ubiquitin-independent function of optineurin in autophagic clearance of protein aggregates (English)

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23 September 2017

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GOA release 2020-03-11

author

Ivan Đikić

8

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23 September 2017

Igor Kovacevic

3

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author name string

Jelena Korac

1

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23 September 2017

Veronique Schaeffer

2

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23 September 2017

Albrecht M Clement

4

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23 September 2017

Benno Jungblut

5

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23 September 2017

Christian Behl

6

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23 September 2017

Janos Terzic

7

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23 September 2017

language of work or name

English

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publication date

23 November 2012

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23 September 2017

Journal of Cell Science

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23 September 2017

126

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23 September 2017

Pt 2

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23 September 2017

580-592

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describes a project that uses

23 September 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3654196/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Mutant huntingtin impairs post-Golgi trafficking to lysosomes by delocalizing optineurin/Rab8 complex from the Golgi apparatus

25 September 2017

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25 September 2017

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Heterodimer formation of wild-type and amyotrophic lateral sclerosis-causing mutant Cu/Zn-superoxide dismutase induces toxicity independent of protein aggregation

25 September 2017

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Optineurin negatively regulates TNFalpha- induced NF-kappaB activation by competing with NEMO for ubiquitinated RIP

25 September 2017

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Involvement of the ubiquitin-like domain of TBK1/IKK-i kinases in regulation of IFN-inducible genes

25 September 2017

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p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

25 September 2017

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Inhibition of metabotropic glutamate receptor signaling by the huntingtin-binding protein optineurin

25 September 2017

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Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654196

Optineurin in primary open angle glaucoma

25 September 2017

1 reference

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Current status of SOD1 mutations in familial amyotrophic lateral sclerosis

25 September 2017

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FIP-2, a coiled-coil protein, links Huntingtin to Rab8 and modulates cellular morphogenesis

25 September 2017

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25 September 2017

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Sequestosome 1/p62 links familial ALS mutant SOD1 to LC3 via an ubiquitin-independent mechanism.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654196

Novel deletion mutations of OPTN in amyotrophic lateral sclerosis in Japanese.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654196

Plk1-dependent phosphorylation of optineurin provides a negative feedback mechanism for mitotic progression

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654196

Optineurin in Huntington's disease intranuclear inclusions

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654196

Novel heterozygous nonsense mutation of the OPTN gene segregating in a Danish family with ALS.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654196

Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654196

The majority of the genetic risk for Paget’s disease of bone is explained by genetic variants close to the CSF1, OPTN, TM7SF4, and TNFRSF11A genes

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654196

Overexpression of mutant superoxide dismutase 1 causes a motor axonopathy in the zebrafish

2 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3654196

Screening for OPTN mutations in amyotrophic lateral sclerosis in a mainly Caucasian population

2 December 2018

1 reference

12 December 2020

Modeling neurodegenerative diseases in zebrafish embryos

1 reference

12 December 2020

Novel optineurin mutations in patients with familial and sporadic amyotrophic lateral sclerosis

1 reference

12 December 2020

Optineurin in neurodegenerative diseases

1 reference

12 December 2020

Novel optineurin mutations in sporadic amyotrophic lateral sclerosis patients

1 reference

12 December 2020

Optineurin is co-localized with FUS in basophilic inclusions of ALS with FUS mutation and in basophilic inclusion body disease

1 reference

12 December 2020

Selective autophagy: ubiquitin-mediated recognition and beyond

1 reference

12 December 2020

Optineurin inclusions occur in a minority of TDP-43 positive ALS and FTLD-TDP cases and are rarely observed in other neurodegenerative disorders

1 reference

12 December 2020

Identifiers

DOI

10.1242/JCS.114926

1 reference

23 September 2017

1 reference

23 September 2017

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