Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein. (Q44205872)

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14 December 2019

title

Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein (English)

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14 December 2019

author

Maria Grazia Spillantini

15

object named as

Maria Grazia Spillantini

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14 December 2019

14

Bernardino Ghetti

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14 December 2019

author name string

Bridget Allen

1

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14 December 2019

Esther Ingram

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14 December 2019

Masaki Takao

3

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14 December 2019

Michael J Smith

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Ross Jakes

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Kanwar Virdee

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Hirotaka Yoshida

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14 December 2019

Max Holzer

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14 December 2019

Molly Craxton

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14 December 2019

Piers C Emson

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Cristiana Atzori

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14 December 2019

Antonio Migheli

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R Anthony Crowther

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Michel Goedert

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14 December 2019

language of work or name

English

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publication date

1 November 2002

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14 December 2019

published in

Journal of Neuroscience

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14 December 2019

volume

22

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14 December 2019

issue

21

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14 December 2019

page(s)

9340-9351

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Accelerated filament formation from tau protein with specific FTDP-17 missense mutations.

14 December 2019

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The kinase DYRK phosphorylates protein-synthesis initiation factor eIF2Bepsilon at Ser539 and the microtubule-associated protein tau at Thr212: potential role for DYRK as a glycogen synthase kinase 3-priming kinase

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Oligodendroglial tau filament formation in transgenic mice expressing G272V tau.

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Gene expression profiling of the tau mutant (P301L) transgenic mouse brain

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Formation of filamentous tau aggregations in transgenic mice expressing V337M human tau.

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FTDP-17 mutations in tau transgenic mice provoke lysosomal abnormalities and Tau filaments in forebrain

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Neurodegeneration with tau accumulation in a transgenic mouse expressing V337M human tau.

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Activation of the JNK/p38 pathway occurs in diseases characterized by tau protein pathology and is related to tau phosphorylation but not to apoptosis.

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12 December 2020

Phosphorylated mitogen-activated protein kinase (MAPK/ERK-P), protein kinase of 38 kDa (p38-P), stress-activated protein kinase (SAPK/JNK-P), and calcium/calmodulin-dependent kinase II (CaM kinase II) are differentially expressed in tau deposits in

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12 December 2020

Functional effects of tau gene mutations deltaN296 and N296H

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Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila

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Protein kinases--the major drug targets of the twenty-first century?

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p42 MAP kinase phosphorylation sites in microtubule-associated protein tau are dephosphorylated by protein phosphatase 2A1. Implications for Alzheimer's disease [corrected]

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Straight and paired helical filaments in Alzheimer disease have a common structural unit

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12 December 2020

Cloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tau

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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10.1523/JNEUROSCI.22-21-09340.2002

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14 December 2019

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14 December 2019

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