Differential regulation of Rb family proteins and prohibitin during camptothecin-induced apoptosis (Q40722121)

23 September 2017

title

Differential regulation of Rb family proteins and prohibitin during camptothecin-induced apoptosis (English)

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23 September 2017

Gina Fusaro

1

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23 September 2017

Sheng Wang

series ordinal

2

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23 September 2017

Srikumar Chellappan

series ordinal

3

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23 September 2017

language of work or name

English

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publication date

1 July 2002

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23 September 2017

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23 September 2017

volume

21

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23 September 2017

issue

29

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23 September 2017

page(s)

4539-4548

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1205551

23 September 2017

exact match

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cites work

p14ARF links the tumour suppressors RB and p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

Prohibitin family members interact genetically with mitochondrial inheritance components in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

A node between proliferation, apoptosis, and growth arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

Retinoblastoma protein recruits histone deacetylase to repress transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

Mammalian prohibitin proteins respond to mitochondrial stress and decrease during cellular senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

Analysis of estrogen receptor interaction with a repressor of estrogen receptor activity (REA) and the regulation of estrogen receptor transcriptional activity by REA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

The regulation of E2F by pRB-family proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

The Rb/E2F pathway: expanding roles and emerging paradigms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

E2F1-induced apoptosis requires DNA binding but not transactivation and is inhibited by the retinoblastoma protein through direct interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

Role for the p53 homologue p73 in E2F-1-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

Prohibitin antiproliferative activity and lack of heterozygosity in immortalized cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

Differential regulation of retinoblastoma protein function by specific Cdk phosphorylation sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

Cyclin A-kinase regulation of E2F-1 DNA binding function underlies suppression of an S phase checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

A common E2F-1 and p73 pathway mediates cell death induced by TCR activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

Rb interacts with histone deacetylase to repress transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

Retinoblastoma protein represses transcription by recruiting a histone deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

Regulation of E2F1 activity by acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

An estrogen receptor-selective coregulator that potentiates the effectiveness of antiestrogens and represses the activity of estrogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

Apaf-1 is a transcriptional target for E2F and p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

Prohibitins act as a membrane-bound chaperone for the stabilization of mitochondrial proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

E2F-1 cooperates with topoisomerase II inhibition and DNA damage to selectively augment p53-independent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

Prohibitin, an evolutionarily conserved intracellular protein that blocks DNA synthesis in normal fibroblasts and HeLa cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

Key roles for E2F1 in signaling p53-dependent apoptosis and in cell division within developing tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

E2F-1 potentiates cell death by blocking antiapoptotic signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

21 January 2018

E2F-1 induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

Prohibitins regulate membrane protein degradation by the m-AAA protease in mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

Prohibitin, a potential tumor suppressor, interacts with RB and regulates E2F function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

Rb and prohibitin target distinct regions of E2F1 for repression and respond to different upstream signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

Apoptosis is associated with cleavage of a 5 kDa fragment from RB which mimics dephosphorylation and modulates E2F binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

7 January 2021

E2F-1 functions in mice to promote apoptosis and suppress proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

7 January 2021

Specific cleavage of the retinoblastoma protein by an ICE-like protease in apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

7 January 2021

Tumor induction and tissue atrophy in mice lacking E2F-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205551

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205551

1 reference

Dimensions Publication ID

23 September 2017

1004614044

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1 reference