E2F1-dependent miR-421 regulates mitochondrial fragmentation and myocardial infarction by targeting Pink1. (Q40726451)

23 September 2017

E2F1-dependent miR-421 regulates mitochondrial fragmentation and myocardial infarction by targeting Pink1. (English)

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23 September 2017

Kun Wang

1

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23 September 2017

Lu-Yu Zhou

2

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23 September 2017

Jian-Xun Wang

3

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23 September 2017

Yin Wang

4

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23 September 2017

Teng Sun

5

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23 September 2017

Bing Zhao

6

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23 September 2017

Yong-Jie Yang

7

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23 September 2017

Tao An

8

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23 September 2017

Bo Long

9

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23 September 2017

Na Li

10

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23 September 2017

Cui-Yun Liu

11

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23 September 2017

Ying Gong

12

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23 September 2017

Jin-Ning Gao

13

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23 September 2017

Yan-Han Dong

14

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23 September 2017

Jian Zhang

15

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23 September 2017

Pei-Feng Li

16

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23 September 2017

language of work or name

English

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publication date

17 July 2015

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23 September 2017

Nature Communications

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23 September 2017

6

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23 September 2017

7619

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https://scigraph.springernature.com/pub.10.1038/ncomms8619

23 September 2017

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Expanding insights of mitochondrial dysfunction in Parkinson's disease.

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Cytosolic cleaved PINK1 represses Parkin translocation to mitochondria and mitophagy

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Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery

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Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission

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Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin

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PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility

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PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1

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miR-499 regulates mitochondrial dynamics by targeting calcineurin and dynamin-related protein-1

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12 December 2020

MicroRNA 421 suppresses DPC4/Smad4 in pancreatic cancer

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12 December 2020

Distinct and Overlapping Roles for E2F Family Members in Transcription, Proliferation and Apoptosis

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12 December 2020

Inhibiting Drp1-mediated mitochondrial fission selectively prevents the release of cytochrome c during apoptosis

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12 December 2020

Altered microRNA expression in human heart disease

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12 December 2020

Identifiers

DOI

10.1038/NCOMMS8619

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Dimensions Publication ID

23 September 2017

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