Characterisation of the phosphorylation of beta-catenin at the GSK-3 priming site Ser45. (Q40727151)

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9 November 2019

title

Characterisation of the phosphorylation of beta-catenin at the GSK-3 priming site Ser45 (English)

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9 November 2019

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2

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9 November 2019

author name string

Thilo Hagen

series ordinal

1

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9 November 2019

publication date

1 June 2002

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Biochemical and Biophysical Research Communications

9 November 2019

number of pages

5

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based on heuristic

inferred from page(s)

published in

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9 November 2019

volume

294

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9 November 2019

page(s)

324-328

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9 November 2019

issue

2

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Signal transduction by the Wnt family of ligands

9 November 2019

cites work

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GSK3, a master switch regulating cell-fate specification and tumorigenesis

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beta-catenin is a target for the ubiquitin-proteasome pathway

7 January 2021

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Serine phosphorylation-regulated ubiquitination and degradation of beta-catenin

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The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

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beta-catenin signaling and cancer

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The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3

7 January 2021

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Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

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Stabilization of beta-catenin by genetic defects in melanoma cell lines

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Predominant mutation of codon 41 of the beta-catenin proto-oncogene in rat colon tumors induced by 1,2-dimethylhydrazine using a complete carcinogenic protocol

7 January 2021

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Expression and characterization of GSK-3 mutants and their effect on beta-catenin phosphorylation in intact cells

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Wnt signaling controls the phosphorylation status of beta-catenin.

7 January 2021

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A common phosphate binding site explains the unique substrate specificity of GSK3 and its inactivation by phosphorylation

7 January 2021

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Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex

7 January 2021

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Endogenous protein kinase CK2 participates in Wnt signaling in mammary epithelial cells

7 January 2021

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Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription

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Substrate targeting in the ubiquitin system

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Multisite phosphorylation of glycogen synthase from rabbit skeletal muscle. Phosphorylation of site 5 by glycogen synthase kinase-5 (casein kinase-II) is a prerequisite for phosphorylation of sites 3 by glycogen synthase kinase-3

7 January 2021

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Casein kinase I: spatial organization and positioning of a multifunctional protein kinase family

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Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism

7 January 2021

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Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

7 January 2021

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Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly

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A GSK3beta phosphorylation site in axin modulates interaction with beta-catenin and Tcf-mediated gene expression

7 January 2021

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Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex

7 January 2021

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Control of beta-catenin stability: reconstitution of the cytoplasmic steps of the wnt pathway in Xenopus egg extracts

7 January 2021

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10.1016/S0006-291X(02)00485-0

7 January 2021

Identifiers

DOI

1 reference

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9 November 2019

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