Activation of BAD by therapeutic inhibition of epidermal growth factor receptor and transactivation by insulin-like growth factor receptor (Q40732059)

23 September 2017

Activation of BAD by therapeutic inhibition of epidermal growth factor receptor and transactivation by insulin-like growth factor receptor (English)

1 reference

23 September 2017

8

Stanley J Korsmeyer

1 reference

23 September 2017

Andrew P Gilmore

1

1 reference

23 September 2017

Anthony J Valentijn

2

1 reference

23 September 2017

Pengbo Wang

3

1 reference

23 September 2017

Ann M Ranger

4

1 reference

23 September 2017

Nigel Bundred

5

1 reference

23 September 2017

Michael J O'Hare

6

1 reference

23 September 2017

Alan Wakeling

7

1 reference

23 September 2017

Charles H Streuli

9

1 reference

23 September 2017

language of work or name

English

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publication date

13 May 2002

1 reference

Journal of Biological Chemistry

23 September 2017

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23 September 2017

277

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23 September 2017

31

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23 September 2017

27643-27650

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Proliferation, cell cycle and apoptosis in cancer

23 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

The ErbB signaling network: receptor heterodimerization in development and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

BH3 domain of BAD is required for heterodimerization with BCL-XL and pro-apoptotic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Regulation of BAD phosphorylation at serine 112 by the Ras-mitogen-activated protein kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Rsk1 mediates a MEK-MAP kinase cell survival signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Regulation of BAD by cAMP-dependent protein kinase is mediated via phosphorylation of a novel site, Ser155

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Growth factors inactivate the cell death promoter BAD by phosphorylation of its BH3 domain on Ser155.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

BCL-2 family members and the mitochondria in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Multiple signaling pathways of the insulin-like growth factor 1 receptor in protection from apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

14-3-3 proteins and survival kinases cooperate to inactivate BAD by BH3 domain phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Drug-target interactions: only the first step in the commitment to a programmed cell death?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Apoptosis induced by anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Defying death after DNA damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Programmed cell death by default in embryonic cells, fibroblasts, and cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

21 January 2018

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Epidermal growth factor-related peptides and their receptors in human malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Epidermal growth factor receptor tyrosine kinase as a target for anticancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Inhibition of the epidermal growth factor receptor family of tyrosine kinases as an approach to cancer chemotherapy: progression from reversible to irreversible inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

The epidermal growth factor receptor and its inhibition in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Blockade of growth factor receptors in ductal carcinoma in situ inhibits epithelial proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Extracellular matrix regulates apoptosis in mammary epithelium through a control on insulin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Regulation of bad phosphorylation and association with Bcl-x(L) by the MAPK/Erk kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Specific inhibition of epidermal growth factor receptor tyrosine kinase by 4-anilinoquinazolines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Integrins induce activation of EGF receptor: role in MAP kinase induction and adhesion-dependent cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Stimulation of the mitogen-activated protein kinase cascade and tyrosine phosphorylation of the epidermal growth factor receptor by hepatopoietin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

The beta(2)-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

BAD Ser-155 phosphorylation regulates BAD/Bcl-XL interaction and cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

The IRS-1 signaling system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Regulation of neuronal survival by the serine-threonine protein kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Anti-apoptotic signaling of the insulin-like growth factor-I receptor through mitochondrial translocation of c-Raf and Nedd4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Comparison of anti-apoptotic signalling by the insulin receptor and IGF-I receptor in preadipocytes and adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Signaling from E-cadherins to the MAPK pathway by the recruitment and activation of epidermal growth factor receptors upon cell-cell contact formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

In search of the tumour-suppressor functions of BRCA1 and BRCA2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

21 January 2018

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

The role of amphiregulin in breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Prognostic Significance of TGF-α Expression in Breast Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Role of the insulin-like growth factor family in cancer development and progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Tyrosine kinase signalling in breast cancer: insulin-like growth factors and their receptors in breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

ZD1839 ('Iressa') as an anticancer agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Insulin-like Growth Factor 1 Inhibits Apoptosis Using the Phosphatidylinositol 3′-Kinase and Mitogen-activated Protein Kinase Pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

Epidermal growth factor receptor tyrosine kinase inhibitors as anticancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108863200

21 January 2018

Identifiers

DOI

10.1074/JBC.M108863200

1 reference

23 September 2017

1 reference