Signal transduction pathways involving the Raf proto-oncogene (Q40733258)

23 September 2017

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title

Signal transduction pathways involving the Raf proto-oncogene (English)

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23 September 2017

N G Williams

1

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23 September 2017

T M Roberts

series ordinal

2

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23 September 2017

language of work or name

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1 March 1994

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Cancer and Metastasis Reviews

23 September 2017

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23 September 2017

13

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23 September 2017

1

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23 September 2017

105-116

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https://scigraph.springernature.com/pub.10.1007/bf00690421

23 September 2017

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cites work

Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus

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12 December 2020

Activation of extracellular signal-regulated kinase, ERK2, by p21ras oncoprotein

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12 December 2020

Purification and characterization of mitogen-activated protein kinase activator(s) from epidermal growth factor-stimulated A431 cells

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12 December 2020

Activation of mitogen-activated protein kinase kinase by v-Raf in NIH 3T3 cells and in vitro

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12 December 2020

Raf-1 is a potential substrate for mitogen-activated protein kinase in vivo

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12 December 2020

Epidermal growth factor (EGF) stimulates association and kinase activity of Raf-1 with the EGF receptor

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12 December 2020

Activation of human c-raf-1 by replacing the N-terminal region with different sequences

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12 December 2020

Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro

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12 December 2020

Tyrosine kinase-stimulated guanine nucleotide exchange activity of Vav in T cell activation

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12 December 2020

Raf functions downstream of Ras1 in the Sevenless signal transduction pathway

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12 December 2020

Extracellular signal-regulated kinases: ERKs in progress

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12 December 2020

The many roads that lead to Ras.

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12 December 2020

Signal transduction via the MAP kinases: proceed at your own RSK.

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12 December 2020

Complementation of byrl in fission yeast by mammalian MAP kinase kinase requires coexpression of Raf kinase

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12 December 2020

Suppression of c-ras transformation by GTPase-activating protein

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12 December 2020

Activation of the MAP kinase pathway by the protein kinase raf

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12 December 2020

A signal chain of events

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12 December 2020

The phosphorylation and activation of B-raf in PC12 cells stimulated by nerve growth factor

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12 December 2020

Direct activation of the serine/threonine kinase activity of Raf-1 through tyrosine phosphorylation by the PDGF beta-receptor

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12 December 2020

Serine- and threonine-specific protein kinase activities of purified gag-mil and gag-raf proteins

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12 December 2020

B-raf, a new member of the raf family, is activated by DNA rearrangement

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12 December 2020

Ras activation by insulin and epidermal growth factor through enhanced exchange of guanine nucleotides on p21ras

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12 December 2020

A novel membrane factor stimulates guanine nucleotide exchange reaction of ras proteins.

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12 December 2020

New mammalian transforming retrovirus: demonstration of a polyprotein gene product

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12 December 2020

T cell antigen receptor engagement stimulates c-raf phosphorylation and induces c-raf-associated kinase activity via a protein kinase C-dependent pathway

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12 December 2020

Oncogenes and signal transduction

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12 December 2020

Critical role of cellular ras proteins in proliferative signal transduction.

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12 December 2020

MAP kinase is constitutively activated in gip2 and src transformed rat 1a fibroblasts

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12 December 2020

Identification of the regulatory phosphorylation sites in pp42/mitogen-activated protein kinase (MAP kinase)

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12 December 2020

Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor

1 reference

12 December 2020

A protein factor for ras p21-dependent activation of mitogen-activated protein (MAP) kinase through MAP kinase kinase

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12 December 2020

Structure and biological activity of human homologs of the raf/mil oncogene

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12 December 2020

Granulocyte-macrophage colony-stimulating factor and interleukin-3 induce rapid phosphorylation and activation of the proto-oncogene Raf-1 in a human factor-dependent myeloid cell line.

1 reference

12 December 2020

Raf-1 and p21v-ras cooperate in the activation of mitogen-activated protein kinase

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12 December 2020

Identification of multiple epidermal growth factor-stimulated protein serine/threonine kinases from Swiss 3T3 cells

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12 December 2020

The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product

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12 December 2020

Mitogen-activated protein kinases: versatile transducers for cell signaling

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12 December 2020

Dissection of the protein kinase cascade by which nerve growth factor activates MAP kinases

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12 December 2020

Mitogen-activated protein kinase activation resulting from selective oncogene expression in NIH 3T3 and rat 1a cells

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12 December 2020

Expression of raf family proto-oncogenes in normal mouse tissues

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12 December 2020

Identification of multiple extracellular signal-regulated kinases (ERKs) with antipeptide antibodies

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12 December 2020

The GTPase superfamily: a conserved switch for diverse cell functions

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12 December 2020

Integration of transfected LTR sequences into the c-raf proto-oncogene: activation by promoter insertion

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12 December 2020

Involvement of p21ras in activation of extracellular signal-regulated kinase 2.

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12 December 2020

Stimulation of p21 ras upon T-cell activation

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12 December 2020

Activation of human raf transforming genes by deletion of normal amino-terminal coding sequences

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12 December 2020

Complete coding sequence of a human B-raf cDNA and detection of B-raf protein kinase with isozyme specific antibodies

1 reference

12 December 2020

95-kilodalton B-Raf serine/threonine kinase: identification of the protein and its major autophosphorylation site

1 reference

12 December 2020

Epidermal growth factor regulates the exchange rate of guanine nucleotides on p21ras in fibroblasts

1 reference

12 December 2020

Protein kinase C plays a role in the induction of tyrosine phosphorylation of lymphoid microtubule-associated protein-2 kinase. Evidence for a CD3-associated cascade that includes pp56lck and that is defective in HPB-ALL

1 reference

12 December 2020

Insulin and platelet-derived growth factor stimulate phosphorylation of the c-raf product at serine and threonine residues in intact cells

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12 December 2020

Mutational activation of c-raf-1 and definition of the minimal transforming sequence

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12 December 2020

Differential regulation of the p72-74 RAF-1 kinase in 3T3 fibroblasts expressing ras or src oncogenes.

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12 December 2020

Definition of the human raf amino-terminal regulatory region by deletion mutagenesis

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12 December 2020

The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

1 reference

12 December 2020

Raf-1: A kinase currently without a cause but not lacking in effects

1 reference

12 December 2020

Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1

1 reference

12 December 2020

The complete coding sequence of the human raf oncogene and the corresponding structure of the c-raf-1 gene

1 reference

12 December 2020

Interleukin-2-triggered Raf-1 expression, phosphorylation, and associated kinase activity increase through G1 and S in CD3-stimulated primary human T cells

1 reference

12 December 2020

Activation of the c-Raf protein kinase by protein kinase C phosphorylation

1 reference

12 December 2020

MAP kinase activator from insulin-stimulated skeletal muscle is a protein threonine/tyrosine kinase

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12 December 2020

Insulin activates the kinase activity of the Raf-1 proto-oncogene by increasing its serine phosphorylation

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12 December 2020

Identification of a transforming activity suppressing sequence in the c-raf oncogene

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12 December 2020

Identification of the major phosphorylation sites of the Raf-1 kinase.

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12 December 2020

A cytosolic protein catalyzes the release of GDP from p21ras

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12 December 2020

Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase

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12 December 2020

Molecular cloning of an activated human oncogene, homologous to v-raf, from primary stomach cancer

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12 December 2020

Reconstitution of the Raf-1-MEK-ERK signal transduction pathway in vitro

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12 December 2020

Colony stimulating factor-1 (CSF-1) stimulates temperature dependent phosphorylation and activation of the RAF-1 proto-oncogene product

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12 December 2020

Primary Structure of v- raf : Relatedness to the src Family of Oncogenes

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12 December 2020

Raf-1 activates MAP kinase-kinase

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12 December 2020

Both p21ras and pp60v-src are required, but neither alone is sufficient, to activate the Raf-1 kinase

1 reference

12 December 2020

Xenopus MAP kinase activator: identification and function as a key intermediate in the phosphorylation cascade

1 reference

12 December 2020

ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF

1 reference

12 December 2020

Role of protein kinase C in T-cell antigen receptor regulation of p21ras: evidence that two p21ras regulatory pathways coexist in T cells

1 reference

12 December 2020

MAP kinases: charting the regulatory pathways

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12 December 2020

Form and Function of Retroviral Proviruses

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12 December 2020

Ras is essential for nerve growth factor- and phorbol ester-induced tyrosine phosphorylation of MAP kinases

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12 December 2020

A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants

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12 December 2020

Signal transduction from membrane to cytoplasm: growth factors and membrane-bound oncogene products increase Raf-1 phosphorylation and associated protein kinase activity

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12 December 2020

Evidence that extracellular signal-regulated kinases are the insulin-activated Raf-1 kinase kinases

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12 December 2020

ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK

1 reference

12 December 2020

Evidence for a Ras-dependent extracellular signal-regulated protein kinase (ERK) cascade

1 reference

12 December 2020

The amino acid sequence of a mammalian MAP kinase kinase

1 reference

12 December 2020

Requirements for Phosphorylation of Map Kinase During Meiosis in Xenopus Oocytes

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12 December 2020

A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf

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12 December 2020

Requirement for c-ras proteins during viral oncogene transformation

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12 December 2020

Erythropoietin induces Raf-1 activation and Raf-1 is required for erythropoietin-mediated proliferation

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12 December 2020

Control of cell fate determination by p21ras/Ras1, an essential component of torso signaling in Drosophila.

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12 December 2020

Proliferation of both somatic and germ cells is affected in the Drosophila mutants of raf proto-oncogene

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12 December 2020

Drosophila melanogaster homologs of the raf oncogene

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12 December 2020

How does p21ras transform cells?

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12 December 2020

Interleukin-3 and granulocyte-macrophage colony-stimulating factor mediate rapid phosphorylation and activation of cytosolic c-raf

1 reference

12 December 2020

The complete coding sequence of the human A-raf-1 oncogene and transforming activity of a human A-raf carrying retrovirus

1 reference

12 December 2020

Interleukin 2 induces tyrosine phosphorylation and activation of p72-74 Raf-1 kinase in a T-cell line

1 reference

12 December 2020

Molecular structure of a protein-tyrosine/threonine kinase activating p42 mitogen-activated protein (MAP) kinase: MAP kinase kinase

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF00690421

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Dimensions Publication ID

23 September 2017

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