Phosphorylation of HDM2 by Akt. (Q40737405)

23 September 2017

Phosphorylation of HDM2 by Akt. (English)

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23 September 2017

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7

Karen H Vousden

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23 September 2017

Margaret Ashcroft

1

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23 September 2017

Robert L Ludwig

2

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23 September 2017

Douglas B Woods

3

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23 September 2017

Terry D Copeland

4

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23 September 2017

H Oliver Weber

5

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23 September 2017

Elizabeth J MacRae

6

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23 September 2017

language of work or name

English

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publication date

1 March 2002

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23 September 2017

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23 September 2017

21

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23 September 2017

13

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23 September 2017

1955-1962

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1205276

23 September 2017

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cites work

The selective and inducible activation of endogenous PI 3-kinase in PC12 cells results in efficient NGF-mediated survival but defective neurite outgrowth

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205276

7 January 2021

Stress signals utilize multiple pathways to stabilize p53

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205276

7 January 2021

SUMO-1 modification of Mdm2 prevents its self-ubiquitination and increases Mdm2 ability to ubiquitinate p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205276

7 January 2021

Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205276

7 January 2021

Mapping of the p53 and mdm-2 interaction domains

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205276

7 January 2021

Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205276

7 January 2021

The mdm-2 oncogene can overcome wild-type p53 suppression of transformed cell growth

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205276

7 January 2021

Akt signaling: linking membrane events to life and death decisions

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205276

7 January 2021

Functions of the MDM2 oncoprotein

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205276

7 January 2021

Identification of a CK2 phosphorylation site in mdm2.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205276

7 January 2021

The carboxy terminus of p53 mimics the polylysine effect of protein kinase CK2-catalyzed MDM2 phosphorylation

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1205276

7 January 2021

Multiple sites of in vivo phosphorylation in the MDM2 oncoprotein cluster within two important functional domains

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205276

7 January 2021

Activity of MDM2, a ubiquitin ligase, toward p53 or itself is dependent on the RING finger domain of the ligase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205276

7 January 2021

Induction of NF-kappaB by the Akt/PKB kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205276

7 January 2021

Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205276

7 January 2021

Keeping an old friend under control: regulation of p53 stability.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205276

7 January 2021

Insulin-like growth factor-1 induces Mdm2 and down-regulates p53, attenuating the myocyte renin-angiotensin system and stretch-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205276

7 January 2021

The MDM2 C-terminal region binds to TAFII250 and is required for MDM2 regulation of the cyclin A promoter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205276

7 January 2021

Identification of a cryptic nucleolar-localization signal in MDM2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205276

7 January 2021

ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205276

7 January 2021

A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205276

7 January 2021

Amplification of a gene encoding a p53-associated protein in human sarcomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205276

7 January 2021

Opposing effects of Ras on p53: transcriptional activation of mdm2 and induction of p19ARF.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205276

7 January 2021

Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205276

7 January 2021

Induction of Mdm2 and enhancement of cell survival by bFGF.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205276

7 January 2021

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205276

7 January 2021

Repression of p53-mediated transcription by MDM2: a dual mechanism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205276

7 January 2021

Cooperative signals governing ARF-mdm2 interaction and nucleolar localization of the complex.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205276

7 January 2021

Regulation of p53 function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205276

7 January 2021

Cyclin a-CDK phosphorylation regulates MDM2 protein interactions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205276

7 January 2021

HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205276

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205276

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Dimensions Publication ID

23 September 2017

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1 reference