Role of Ras in metal-induced EGF receptor signaling and NF-kappaB activation in human airway epithelial cells (Q40739175)

23 September 2017

Role of Ras in metal-induced EGF receptor signaling and NF-kappaB activation in human airway epithelial cells (English)

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23 September 2017

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Weidong Wu

1

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23 September 2017

Ilona Jaspers

2

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23 September 2017

Wenli Zhang

3

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23 September 2017

Lee M Graves

4

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23 September 2017

James M Samet

5

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23 September 2017

1 May 2002

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American Journal of Physiology - Lung Cellular and Molecular Physiology

23 September 2017

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23 September 2017

282

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23 September 2017

5

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23 September 2017

L1040-8

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Lead, zinc, cadmium, mercury, selenium and copper in Greenland caribou and reindeer (Rangifer tarandus).

23 September 2017

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

NF-kappa B: ten years after

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

The NF-kappa B and I kappa B proteins: new discoveries and insights

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Fluid shear stress activation of IkappaB kinase is integrin-dependent

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Cell type-specific role for reactive oxygen species in nuclear factor-kappaB activation by interleukin-1.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

The GTPase superfamily: conserved structure and molecular mechanism

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Oxidative stress and nuclear factor-kappaB activation: a reassessment of the evidence in the light of recent discoveries.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Inducible expression of Ras N17 dominant inhibitory protein

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Dbl and the Rho GTPases activate NF kappa B by I kappa B kinase (IKK)-dependent and IKK-independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Cytokine production by human airway epithelial cells after exposure to an air pollution particle is metal-dependent

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Vanadate induction of NF-kB involves IkB kinase B and SAPK/ERK kinasa 1 in macrophages

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Ozone-induced release of cytokines and fibronectin by alveolar macrophages and airway epithelial cells

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Interaction of Rac with p67phox and regulation of phagocytic NADPH oxidase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Structure and function of the protein tyrosine phosphatases

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Evidence for a Ras/Ral signaling cascade

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Growth factors and mitogen-activated protein kinases

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

A specific inhibitor of the epidermal growth factor receptor tyrosine kinase

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Oncogenic Ha-Ras-dependent mitogen-activated protein kinase activity requires signaling through the epidermal growth factor receptor

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Cooperativity between oxidants and tumor necrosis factor in the activation of nuclear factor (NF)-kappaB: requirement of Ras/mitogen-activated protein kinases in the activation of NF-kappaB by oxidants

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Vanadium-induced kappaB-dependent transcription depends upon peroxide-induced activation of the p38 mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Residual oil fly ash induces cytotoxicity and mucin secretion by guinea pig tracheal epithelial cells via an oxidant-mediated mechanism

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Identification of AF-6 and canoe as putative targets for Ras.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Substrate targeting in the ubiquitin system

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Activation of NF-kappaB via a Src-dependent Ras-MAPK-pp90rsk pathway is required for Pseudomonas aeruginosa-induced mucin overproduction in epithelial cells

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

A ubiquitin ligase complex essential for the NF-kappaB, Wnt/Wingless, and Hedgehog signaling pathways

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Zinc exposure in Chinese foundry workers

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Signal transduction through NF-kappa B.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Multiple signals converging on NF-kappaB.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

The response of a human bronchial epithelial cell line to histamine: intracellular calcium changes and extracellular release of inflammatory mediators

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Oncogenic Ras enhances NF-kappaB transcriptional activity through Raf-dependent and Raf-independent mitogen-activated protein kinase signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Air pollution particles induce IL-6 gene expression in human airway epithelial cells via NF-kappaB activation

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Role of transcription factors in inflammatory lung diseases

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Identification and characterization of an IkappaB kinase

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Phosphatidylinositol-3-OH kinase as a direct target of Ras

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Arsenic inhibits NF-kappaB-mediated gene transcription by blocking IkappaB kinase activity and IkappaBalpha phosphorylation and degradation

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Direct interaction between Ras and the kinase domain of mitogen-activated protein kinase kinase kinase (MEKK1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Tyrosine phosphatases as targets in metal-induced signaling in human airway epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Disruption of protein tyrosine phosphate homeostasis in bronchial epithelial cells exposed to oil fly ash.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Inhibition of NF-kappa B binding to DNA by chromium, cadmium, mercury, zinc, and arsenite in vitro: evidence of a thiol mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

NF-kappaB-inducing kinase and IkappaB kinase participate in human T-cell leukemia virus I Tax-mediated NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Particulate matter initiates inflammatory cytokine release by activation of capsaicin and acid receptors in a human bronchial epithelial cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Increasing complexity of the Ras signaling pathway.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

I kappa B proteins: structure, function and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Activation of the EGF receptor signaling pathway in human airway epithelial cells exposed to metals

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Identification of the receptor component of the IkappaBalpha-ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

ras p21 and GAP inhibit coupling of muscarinic receptors to atrial K+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Induction of TNFalpha in macrophages by vanadate is dependent on activation of transcription factor NF-KB and free radical reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

MEK kinase 1 (MEKK1) transduces c-Jun NH2-terminal kinase activation in response to changes in the microtubule cytoskeleton.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

Direct Phosphorylation of IB by IKK and IKK: Discrimination Between Free and NF-B-Bound Substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

The pathway to signal achievement

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00390.2001

10.1152/AJPLUNG.00390.2001

21 January 2018

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DOI

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23 September 2017

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