Hedgehog-stimulated phosphorylation of the kinesin-related protein Costal2 is mediated by the serine/threonine kinase fused (Q40740015)

23 September 2017

Hedgehog-stimulated phosphorylation of the kinesin-related protein Costal2 is mediated by the serine/threonine kinase fused (English)

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23 September 2017

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GOA release 2020-03-11

Costa Dmel_CG1708

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GOA release 2020-03-11

Fused Dmel_CG6551

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GOA release 2020-03-11

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Kent E Nybakken

1

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23 September 2017

Christoph W Turck

series ordinal

2

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23 September 2017

David J Robbins

series ordinal

3

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23 September 2017

J Michael Bishop

series ordinal

4

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23 September 2017

language of work or name

English

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publication date

4 April 2002

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Journal of Biological Chemistry

23 September 2017

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23 September 2017

277

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23 September 2017

27

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23 September 2017

24638-24647

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Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity

23 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Sonic hedgehog mediates the polarizing activity of the ZPA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

The Drosophila hedgehog gene is expressed specifically in posterior compartment cells and is a target of engrailed regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Identification of Sonic hedgehog as a candidate gene responsible for holoprosencephaly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

The role of the human homologue of Drosophila patched in sporadic basal cell carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Altered neural cell fates and medulloblastoma in mouse patched mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Human homolog of patched, a candidate gene for the basal cell nevus syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Basal cell carcinomas in mice overexpressing sonic hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Mutations in the human Sonic Hedgehog gene cause holoprosencephaly

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

No evidence for the H133Y mutation in SONIC HEDGEHOG in a collection of common tumour types

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Activating Smoothened mutations in sporadic basal-cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Identification of a palmitic acid-modified form of human Sonic hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

The product of hedgehog autoproteolytic cleavage active in local and long-range signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Hedgehog patterning activity: role of a lipophilic modification mediated by the carboxy-terminal autoprocessing domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Dual roles for patched in sequestering and transducing Hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

The Drosophila patched gene encodes a putative membrane protein required for segmental patterning

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

A protein with several possible membrane-spanning domains encoded by the Drosophila segment polarity gene patched

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Interactions between segment polarity genes and the generation of the segmental pattern in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Role of the Drosophila patched gene in positional signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

The Drosophila smoothened gene encodes a seven-pass membrane protein, a putative receptor for the hedgehog signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

smoothened encodes a receptor-like serpentine protein required for hedgehog signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Transcriptional activation of hedgehog target genes in Drosophila is mediated directly by the cubitus interruptus protein, a member of the GLI family of zinc finger DNA-binding proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Sending and receiving the hedgehog signal: control by the Drosophila Gli protein Cubitus interruptus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Repression of ci-D in posterior compartments of Drosophila by engrailed

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

The Drosophila cubitus interruptus protein and its role in the wingless and hedgehog signal transduction pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Cloning and characterization of the segment polarity gene cubitus interruptus Dominant of Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Proteolysis that is inhibited by hedgehog targets Cubitus interruptus protein to the nucleus and converts it to a repressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Nuclear trafficking of Cubitus interruptus in the transcriptional regulation of Hedgehog target gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Modulation of Hedgehog target gene expression by the Fused serine-threonine kinase in wing imaginal discs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Hedgehog stimulates maturation of Cubitus interruptus into a labile transcriptional activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

A putative serine/threonine protein kinase encoded by the segment-polarity fused gene of Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Molecular organisation and expression pattern of the segment polarity gene fused of Drosophila melanogaster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Costal2, a novel kinesin-related protein in the Hedgehog signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Hedgehog elicits signal transduction by means of a large complex containing the kinesin-related protein costal2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Phosphorylation of the fused protein kinase in response to signaling from hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Identification of a tetrameric hedgehog signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

The substrate specificity of the snail Lymnaea stagnalis UDP-GlcNAc:GlcNAc beta-R beta 4-N-acetylglucosaminyltransferase reveals a novel variant pathway of complex-type oligosaccharide synthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Functional expression of eukaryotic polypeptide chain release factors 1 and 3 by means of baculovirus/insect cells and complex formation between the factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Multisite autophosphorylation of p21-activated protein kinase gamma-PAK as a function of activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Purification and characterization of recombinant baculovirus-expressed mouse DNA methyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Regulating the yeast kinetochore by ubiquitin-dependent degradation and Skp1p-mediated phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

A role for casein kinase II phosphorylation in the regulation of IRF-1 transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Effect of gamma subunit carboxyl methylation on the interaction of G protein alpha subunits with beta gamma subunits of defined composition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Requirements of protein kinase cdelta for catalytic function. Role of glutamic acid 500 and autophosphorylation on serine 643

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Differential substrate recognition capabilities of Janus family protein tyrosine kinases within the interleukin 2 receptor (IL2R) system: Jak3 as a potential molecular target for treatment of leukemias with a hyperactive Jak-Stat signaling machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Phosphorylation by p34cdc2 protein kinase regulates binding of the kinesin-related motor HsEg5 to the dynactin subunit p150

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Role of the kinesin neck linker and catalytic core in microtubule-based motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

The design plan of kinesin motors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Protein kinase A directly regulates the activity and proteolysis of cubitus interruptus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Protein kinase A antagonizes Hedgehog signaling by regulating both the activator and repressor forms of Cubitus interruptus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Characterization of KIF1C, a new kinesin-like protein involved in vesicle transport from the Golgi apparatus to the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Phosphotransferases associated with the regulation of kinesin motor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

The carboxyl-terminal domain of the protein kinase fused can function as a dominant inhibitor of hedgehog signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Improvement of an "In-Gel" digestion procedure for the micropreparation of internal protein fragments for amino acid sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

The Xenopus laevis aurora-related protein kinase pEg2 associates with and phosphorylates the kinesin-related protein XlEg5

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Phosphorylation of kinesin in vivo correlates with organelle association and neurite outgrowth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

Changes in kinesin distribution and phosphorylation occur during regulated secretion in pancreatic acinar cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110730200

21 January 2018

Identifiers

DOI

10.1074/JBC.M110730200

1 reference

23 September 2017

1 reference